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The eIF2-alpha kinase HRI: a potential target beyond the red blood cell

Expert opinion on therapeutic targets, 2017-12, Vol.21 (12), p.1171-1177

2017

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SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro

Frontiers in cellular and infection microbiology, 2021-07, Vol.11, p.701278-701278

2021

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Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins

Nature communications, 2020-05, Vol.11 (1), p.2280-2280, Article 2280

2020

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Endothelial cell infection and dysfunction, immune activation in severe COVID-19

Theranostics, 2021-01, Vol.11 (16), p.8076-8091

2021

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Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis

Cancer research (Chicago, Ill.), 2011-03, Vol.71 (6), p.2298-2307

2011

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Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation

Cancer research (Chicago, Ill.), 2001-08, Vol.61 (16), p.6213-6218

2001

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Small-Molecule targeting of translation initiation for cancer therapy

Oncotarget, 2013-10, Vol.4 (10), p.1606-1617

2013

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Restriction of drug transport by the tumor environment

Histochemistry and cell biology, 2018-12, Vol.150 (6), p.631-648

2018

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Evaluation of deficit irrigation for efficient sheep production from permanent sown pastures in a dry continental climate

Agricultural water management, 2013-03, Vol.119, p.135-143

2013

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Embryonic Lethal Abnormal Vision-like HuR-dependent mRNA Stability Regulates Post-transcriptional Expression of Cyclin-dependent Kinase Inhibitor p27Kip1

The Journal of biological chemistry, 2010-05, Vol.285 (20), p.15408-15419

2010

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Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target

Nature chemical biology, 2011-09, Vol.7 (9), p.610-616

2011

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Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis

Scientific reports, 2017-12, Vol.7 (1), p.17074-11, Article 17074

2017

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Development of 1‑((1,4-trans)‑4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5392-5406

2017

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In vitro inhibition of translation initiation by N,N′-diarylureas—potential anti-cancer agents

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.402-409

2012

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Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G

Cell, 2007-01, Vol.128 (2), p.257-267

2007

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Prevalence of Dirofilaria immitis in dogs from Hatay province, Turkey

Journal of helminthology, 2009-09, Vol.83 (3), p.255-260

2009

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Depletion of eIF2·GTP·Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo

Oncotarget, 2015-03, Vol.6 (9), p.6902-6914

2015

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Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAiMet ternary complex inhibitors

European journal of medicinal chemistry, 2013-11, Vol.69, p.537-553

2013

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Novel Arylsulfoanilide−Oxindole Hybrid as an Anticancer Agent That Inhibits Translation Initiation

Journal of medicinal chemistry, 2004-10, Vol.47 (21), p.4979-4982

2004

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Translational Regulation of Gene Expression by ω-3 Fatty Acids

The Journal of nutrition, 2004-09, Vol.134 (9), p.2487S-2491S

2004

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Deficiency of the Mouse Complement Regulatory Protein mCd59b Results in Spontaneous Hemolytic Anemia with Platelet Activation and Progressive Male Infertility

Immunity (Cambridge, Mass.), 2003-02, Vol.18 (2), p.217-227

2003

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Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1

Molecular and Cellular Biology, 1997-07, Vol.17 (7), p.3850-3857

1997

Volltextzugriff (PDF)

Inhibition of translation initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid

Cancer research (Chicago, Ill.), 2000-06, Vol.60 (11), p.2919-2925

2000

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Maintenance of meiotic arrest by increasing [cAMP]i may have physiological relevance in bovine oocytes

Journal of reproduction & fertility, 1995-11, Vol.105 (2), p.237-245

1995

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Maintenance of bovine oocytes in prophase of meiosis I by high [cAMP]i

Journal of reproduction & fertility, 1995-11, Vol.105 (2), p.227-235

1995

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The eIF2-alpha kinase HRI: a potential target beyond the red blood cell

SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro

Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins

Endothelial cell infection and dysfunction, immune activation in severe COVID-19

Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis

Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation

Small-Molecule targeting of translation initiation for cancer therapy

Restriction of drug transport by the tumor environment

Evaluation of deficit irrigation for efficient sheep production from permanent sown pastures in a dry continental climate

Embryonic Lethal Abnormal Vision-like HuR-dependent mRNA Stability Regulates Post-transcriptional Expression of Cyclin-dependent Kinase Inhibitor p27Kip1

Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target

Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis

Development of 1‑((1,4-trans)‑4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response

In vitro inhibition of translation initiation by N,N′-diarylureas—potential anti-cancer agents

Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G

Prevalence of Dirofilaria immitis in dogs from Hatay province, Turkey

Depletion of eIF2·GTP·Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo

Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAiMet ternary complex inhibitors

Novel Arylsulfoanilide−Oxindole Hybrid as an Anticancer Agent That Inhibits Translation Initiation

Translational Regulation of Gene Expression by ω-3 Fatty Acids

Deficiency of the Mouse Complement Regulatory Protein mCd59b Results in Spontaneous Hemolytic Anemia with Platelet Activation and Progressive Male Infertility

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1

Inhibition of translation initiation mediates the anticancer effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid

Maintenance of meiotic arrest by increasing [cAMP]i may have physiological relevance in bovine oocytes

Maintenance of bovine oocytes in prophase of meiosis I by high [cAMP]i

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