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The Genetics of Pulmonary Arterial Hypertension

Circulation research, 2014-06, Vol.115 (1), p.189-202

2014

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Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects

Human mutation, 2015-12, Vol.36 (12), p.1113-1127

2015

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TBX4 Transcription Factor Is a Positive Feedback Regulator of Itself and Phospho-SMAD1/5

American journal of respiratory cell and molecular biology, 2021-01, Vol.64 (1), p.140-143

2021

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KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models

International journal of molecular sciences, 2021-05, Vol.22 (9), p.5014

2021

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Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction

The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2262-2276

2017

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Heterozygous Null Bone Morphogenetic Protein Receptor Type 2 Mutations Promote SRC Kinase-dependent Caveolar Trafficking Defects and Endothelial Dysfunction in Pulmonary Arterial Hypertension

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.960-971

2015

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Abnormal trafficking of endogenously expressed BMPR2 mutant allelic products in patients with heritable pulmonary arterial hypertension

PloS one, 2013-11, Vol.8 (11), p.e80319-e80319

2013

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Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2016-05, Vol.133 (20), p.1936-1944

2016

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Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects

The European respiratory journal, 2017-08, Vol.50 (2), p.1602337-1602337

2017

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Evidence for Right Ventricular Lipotoxicity in Heritable Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2014-02, Vol.189 (3), p.325-334

2014

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4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension

American journal of respiratory cell and molecular biology, 2020-08, Vol.63 (2), p.160-171

2020

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Molecular Function and Contribution of TBX4 in Development and Disease

American journal of respiratory and critical care medicine, 2023-04, Vol.207 (7), p.855-864

2023

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Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II–Associated Pulmonary Arterial Hypertension Through MicroRNA-29–Mediated Modulation of Cellular Metabolism

Circulation (New York, N.Y.), 2016-01, Vol.133 (1), p.82-97

2016

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FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2019-01, Vol.199 (1), p.83-98

2019

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Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension

Molecular biology of the cell, 2017-05, Vol.28 (9), p.1177-1185

2017

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Genetics of Pulmonary Arterial Hypertension

Seminars in respiratory and critical care medicine, 2017-10, Vol.38 (5), p.585-595

2017

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Letter by Mosley Regarding Article, “Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat”

Circulation research, 2015-08, Vol.117 (6), p.e56-e57

2015

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Programmatic change: lung disease research in the era of induced pluripotency

American journal of physiology. Lung cellular and molecular physiology, 2011-12, Vol.301 (6), p.L830-L835

2011

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Short gut syndrome : Treatment by neovascularization of the small intestine

Annals of plastic surgery, 1996-07, Vol.37 (1), p.84-90

1996

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A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6270), p.271-275

2016

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BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors

PloS one, 2018-07, Vol.13 (7), p.e0200826

2018

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A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

The European respiratory journal, 2018-06, Vol.51 (6), p.1702638-1702638

2018

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Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

Nature communications, 2021-12, Vol.12 (1), p.7325-7325, Article 7325

2021

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The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

PloS one, 2021-01, Vol.16 (1), p.e0244439

2021

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The Genetics of Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects

TBX4 Transcription Factor Is a Positive Feedback Regulator of Itself and Phospho-SMAD1/5

KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models

Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction

Heterozygous Null Bone Morphogenetic Protein Receptor Type 2 Mutations Promote SRC Kinase-dependent Caveolar Trafficking Defects and Endothelial Dysfunction in Pulmonary Arterial Hypertension

Abnormal trafficking of endogenously expressed BMPR2 mutant allelic products in patients with heritable pulmonary arterial hypertension

Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension

Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects

Evidence for Right Ventricular Lipotoxicity in Heritable Pulmonary Arterial Hypertension

4PBA Restores Signaling of a Cysteine-substituted Mutant BMPR2 Receptor Found in Patients with Pulmonary Arterial Hypertension

Molecular Function and Contribution of TBX4 in Development and Disease

Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II–Associated Pulmonary Arterial Hypertension Through MicroRNA-29–Mediated Modulation of Cellular Metabolism

FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension

Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension

Genetics of Pulmonary Arterial Hypertension

Letter by Mosley Regarding Article, “Iron Homeostasis and Pulmonary Hypertension: Iron Deficiency Leads to Pulmonary Vascular Remodeling in the Rat”

Programmatic change: lung disease research in the era of induced pluripotency

Short gut syndrome : Treatment by neovascularization of the small intestine

A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle

BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

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