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A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomers

Nature communications, 2018-03, Vol.9 (1), p.1097-14, Article 1097

2018

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Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

Immunity (Cambridge, Mass.), 2016-10, Vol.45 (4), p.817-830

2016

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Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

Cell, 2016-05, Vol.165 (5), p.1081-1091

2016

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A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6206), p.237-241

2014

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A Mouse Model of Zika Virus Pathogenesis

Cell host & microbe, 2016-05, Vol.19 (5), p.720-730

2016

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Oral Intoxication of Mice with Shiga Toxin Type 2a (Stx2a) and Protection by Anti-Stx2a Monoclonal Antibody 11E10

Infection and Immunity, 2014-03, Vol.82 (3), p.1213-1221

2014

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Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

Immunity (Cambridge, Mass.), 2014-07, Vol.41 (1), p.75-88

2014

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Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis

Arthritis & rheumatology (Hoboken, N.J.), 2016-04, Vol.68 (4), p.868-879

2016

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Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

Osteoarthritis and cartilage, 2011-07, Vol.19 (7), p.874-885

2011

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Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (2), p.E310-E316

2018

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TNF Counterbalances the Emergence of M2 Tumor Macrophages

Cell reports (Cambridge), 2015-09, Vol.12 (11), p.1902-1914

2015

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Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

Nature communications, 2022-01, Vol.13 (1), p.135-135, Article 135

2022

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Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Nature immunology, 2014-09, Vol.15 (9), p.846-855

2014

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Engram Cell Excitability State Determines the Efficacy of Memory Retrieval

Neuron (Cambridge, Mass.), 2019-01, Vol.101 (2), p.274-284.e5

2019

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Nature, 2005-04, Vol.434 (7035), p.917-921

2005

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Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

Nature biotechnology, 2014-02, Vol.32 (2), p.191-198

2014

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Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

Molecular cell, 2011-01, Vol.41 (2), p.139-149

2011

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An anatomically comprehensive atlas of the adult human brain transcriptome

Nature (London), 2012-09, Vol.489 (7416), p.391-399

2012

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Developmental switch of leptin signaling in arcuate nucleus neurons

The Journal of neuroscience, 2014-07, Vol.34 (30), p.9982-9994

2014

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Polymerase θ inhibition steps on the cGAS pedal

The Journal of clinical investigation, 2023-06, Vol.133 (11)

2023

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Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

Immunity (Cambridge, Mass.), 2012-08, Vol.37 (2), p.339-350

2012

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Myeloid-Derived Suppressor Activity Is Mediated by Monocytic Lineages Maintained by Continuous Inhibition of Extrinsic and Intrinsic Death Pathways

Immunity (Cambridge, Mass.), 2014-12, Vol.41 (6), p.947-959

2014

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Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

Science (American Association for the Advancement of Science), 2012-04, Vol.336 (6077), p.91-95

2012

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Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform

Developmental cell, 2019-09, Vol.50 (5), p.627-643.e5

2019

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Depletion of Protease‐Activated Receptor 2 but Not Protease‐Activated Receptor 1 May Confer Protection Against Osteoarthritis in Mice Through Extracartilaginous Mechanisms

Arthritis & rheumatology (Hoboken, N.J.), 2014-12, Vol.66 (12), p.3337-3348

2014

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A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomers

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

A Mouse Model of Zika Virus Pathogenesis

Oral Intoxication of Mice with Shiga Toxin Type 2a (Stx2a) and Protection by Anti-Stx2a Monoclonal Antibody 11E10

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis

Locus coeruleus input to hippocampal CA3 drives single-trial learning of a novel context

TNF Counterbalances the Emergence of M2 Tumor Macrophages

Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Engram Cell Excitability State Determines the Efficacy of Memory Retrieval

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction

An anatomically comprehensive atlas of the adult human brain transcriptome

Developmental switch of leptin signaling in arcuate nucleus neurons

Polymerase θ inhibition steps on the cGAS pedal

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease

Myeloid-Derived Suppressor Activity Is Mediated by Monocytic Lineages Maintained by Continuous Inhibition of Extrinsic and Intrinsic Death Pathways

Interleukin-22 Drives Endogenous Thymic Regeneration in Mice

Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform

Depletion of Protease‐Activated Receptor 2 but Not Protease‐Activated Receptor 1 May Confer Protection Against Osteoarthritis in Mice Through Extracartilaginous Mechanisms

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