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Clinical and Molecular Pharmacology of Etomidate

Anesthesiology (Philadelphia), 2011-03, Vol.114 (3), p.695-707

FORMAN, Stuart A

2011

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Etomidate versus ketamine for emergency endotracheal intubation: a randomized clinical trial

Intensive care medicine, 2022, Vol.48 (1), p.78-91

2022

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An Etomidate Analogue With Less Adrenocortical Suppression, Stable Hemodynamics, and Improved Behavioral Recovery in Rats

Anesthesia and analgesia, 2017-08, Vol.125 (2), p.442-450

2017

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Etomidate Continuous Infusion for Procedural Sedation: A Case Series and Assessment of Feasibility

Anesthesia and analgesia, 2024-06, Vol.138 (6), p.1342

2024

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Etomidate Infusion for Procedural Sedation: Additional Experience

Anesthesia and analgesia, 2024-07, Vol.139 (1), p.e6

2024

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The effect of etomidate on adrenal function in critical illness: a systematic review

Intensive care medicine, 2011-06, Vol.37 (6), p.901-910

2011

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A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics–Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a Single Ascending Bolus Dose

Anesthesiology (Philadelphia), 2017-07, Vol.127 (1), p.20-35

2017

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Modifying Methoxycarbonyl Etomidate Inter-Ester Spacer Optimizes In Vitro Metabolic Stability and In Vivo Hypnotic Potency and Duration of Action

Anesthesiology (Philadelphia), 2012-11, Vol.117 (5), p.1027-1036

2012

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In Vivo and In Vitro Pharmacological Studies of Methoxycarbonyl-Carboetomidate

Anesthesia and analgesia, 2012-08, Vol.115 (2), p.297-304

2012

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Anesthetic Drug Discovery and Development: A Case Study of Novel Etomidate Analogs

Methods in enzymology, 2018, Vol.603, p.153-169

2018

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Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy

Anesthesiology (Philadelphia), 2017-11, Vol.127 (5), p.824-837

2017

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Methoxycarbonyl-etomidate: a novel rapidly metabolized and ultra-short-acting etomidate analogue that does not produce prolonged adrenocortical suppression

Anesthesiology (Philadelphia), 2009-08, Vol.111 (2), p.240-249

2009

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Advancing Novel Anesthetics: Pharmacodynamic and Pharmacokinetic Studies of Cyclopropyl-methoxycarbonyl Metomidate in Dogs

Anesthesiology (Philadelphia), 2014-12, Vol.121 (6), p.1203-1216

2014

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Effects of different doses of alfentanil on cardiovascular response to rapid sequence intubation in elderly patients: a parallel-controlled randomized trial

BMC anesthesiology, 2024-08, Vol.24 (1), p.290-10, Article 290

2024

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Electroencephalographic Recovery, Hypnotic Emergence, and the Effects of Metabolite after Continuous Infusions of a Rapidly Metabolized Etomidate Analog in Rats

Anesthesiology (Philadelphia), 2012-05, Vol.116 (5), p.1057-1065

2012

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ET-26 hydrochloride (ET-26 HCl) has similar hemodynamic stability to that of etomidate in normal and uncontrolled hemorrhagic shock (UHS) rats

PloS one, 2017-08, Vol.12 (8), p.e0183439-e0183439

2017

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Use of etomidate in patients with heart failure undergoing noncardiac surgery

British journal of anaesthesia : BJA, 2020-12, Vol.125 (6), p.943-952

2020

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Modeling the Effect of Excitation on Depth of Anesthesia Monitoring in γ-Aminobutyric Acid Type A Receptor Agonist ABP-700

Anesthesiology (Philadelphia), 2021-01, Vol.134 (1), p.35-51

2021

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Duration of adrenal inhibition following a single dose of etomidate in critically ill patients

Intensive care medicine, 2008-04, Vol.34 (4), p.714-719

2008

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Effect of etomidate and propofol induction on hemodynamic and endocrine response in patients undergoing coronary artery bypass grafting/mitral valve and aortic valve replacement surgery on cardiopulmonary bypass

Annals of cardiac anaesthesia, 2015-04, Vol.18 (2), p.172-178

2015

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Etomidate - a review of robust evidence for its use in various clinical scenarios

Acta anaesthesiologica Scandinavica, 2014-04, Vol.58 (4), p.380-389

2014

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Safety and clinical effect of i.v. infusion of cyclopropyl-methoxycarbonyl etomidate (ABP-700), a soft analogue of etomidate, in healthy subjects

British journal of anaesthesia : BJA, 2018-06, Vol.120 (6), p.1401-1411

2018

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Distinct Hypnotic Recoveries After Infusions of Methoxycarbonyl Etomidate and Cyclopropyl Methoxycarbonyl Metomidate: The Role of the Metabolite

Anesthesia and analgesia, 2016-04, Vol.122 (4), p.1008-1014

2016

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Analogues of Etomidate: Modifications around Etomidate’s Chiral Carbon and the Impact on In Vitro and In Vivo Pharmacology

Anesthesiology (Philadelphia), 2014-08, Vol.121 (2), p.290-301

2014

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Pros and cons of etomidate--more discussion than evidence?

Current opinion in anaesthesiology, 2013-08, Vol.26 (4), p.404-408

2013

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Clinical and Molecular Pharmacology of Etomidate

Etomidate versus ketamine for emergency endotracheal intubation: a randomized clinical trial

An Etomidate Analogue With Less Adrenocortical Suppression, Stable Hemodynamics, and Improved Behavioral Recovery in Rats

Etomidate Continuous Infusion for Procedural Sedation: A Case Series and Assessment of Feasibility

Etomidate Infusion for Procedural Sedation: Additional Experience

The effect of etomidate on adrenal function in critical illness: a systematic review

A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics–Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a Single Ascending Bolus Dose

Modifying Methoxycarbonyl Etomidate Inter-Ester Spacer Optimizes In Vitro Metabolic Stability and In Vivo Hypnotic Potency and Duration of Action

In Vivo and In Vitro Pharmacological Studies of Methoxycarbonyl-Carboetomidate

Anesthetic Drug Discovery and Development: A Case Study of Novel Etomidate Analogs

Competitive Antagonism of Anesthetic Action at the γ-Aminobutyric Acid Type A Receptor by a Novel Etomidate Analog with Low Intrinsic Efficacy

Methoxycarbonyl-etomidate: a novel rapidly metabolized and ultra-short-acting etomidate analogue that does not produce prolonged adrenocortical suppression

Advancing Novel Anesthetics: Pharmacodynamic and Pharmacokinetic Studies of Cyclopropyl-methoxycarbonyl Metomidate in Dogs

Effects of different doses of alfentanil on cardiovascular response to rapid sequence intubation in elderly patients: a parallel-controlled randomized trial

Electroencephalographic Recovery, Hypnotic Emergence, and the Effects of Metabolite after Continuous Infusions of a Rapidly Metabolized Etomidate Analog in Rats

ET-26 hydrochloride (ET-26 HCl) has similar hemodynamic stability to that of etomidate in normal and uncontrolled hemorrhagic shock (UHS) rats

Use of etomidate in patients with heart failure undergoing noncardiac surgery

Modeling the Effect of Excitation on Depth of Anesthesia Monitoring in γ-Aminobutyric Acid Type A Receptor Agonist ABP-700

Duration of adrenal inhibition following a single dose of etomidate in critically ill patients

Effect of etomidate and propofol induction on hemodynamic and endocrine response in patients undergoing coronary artery bypass grafting/mitral valve and aortic valve replacement surgery on cardiopulmonary bypass

Etomidate - a review of robust evidence for its use in various clinical scenarios

Safety and clinical effect of i.v. infusion of cyclopropyl-methoxycarbonyl etomidate (ABP-700), a soft analogue of etomidate, in healthy subjects

Distinct Hypnotic Recoveries After Infusions of Methoxycarbonyl Etomidate and Cyclopropyl Methoxycarbonyl Metomidate: The Role of the Metabolite

Analogues of Etomidate: Modifications around Etomidate’s Chiral Carbon and the Impact on In Vitro and In Vivo Pharmacology

Pros and cons of etomidate--more discussion than evidence?

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