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Population Pharmacokinetics/Pharmacodynamics of 3,4‐Diaminopyridine Free Base in Patients With Lambert‐Eaton Myasthenia

CPT: pharmacometrics and systems pharmacology, 2017-09, Vol.6 (9), p.625-634

2017

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Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries

Naunyn-Schmiedeberg's archives of pharmacology, 2007-03, Vol.375 (1), p.29-38

2007

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Calcium channel subtypes contributing to acetylcholine release from normal, 4‐aminopyridine‐treated and myasthenic syndrome auto‐antibodies‐affected neuromuscular junctions

British journal of pharmacology, 2002-08, Vol.136 (8), p.1135-1145

2002

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Potassium channel subtypes as molecular targets for overactive bladder and other urological disorders

Expert opinion on therapeutic targets, 2004-10, Vol.8 (5), p.437-458

2004

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Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones

Journal of pharmacy and pharmacology, 2006-12, Vol.58 (12), p.1647-1653

2006

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Effects of the chromanol HMR 1556 on potassium currents in atrial myocytes

Naunyn-Schmiedeberg's archives of pharmacology, 2003-03, Vol.367 (3), p.281-288

2003

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An evaluation of a potential calcium channel blocker–lower-extremity edema–loop diuretic prescribing cascade

Journal of the American Pharmacists Association, 2018-09, Vol.58 (5), p.534-539.e4

2018

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Treatment of internuclear ophthalmoparesis in multiple sclerosis with fampridine: A randomized double‐blind, placebo‐controlled cross‐over trial

CNS neuroscience & therapeutics, 2019-06, Vol.25 (6), p.697-703

2019

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Acetylator Status Impacts Amifampridine Phosphate (Firdapse™) Pharmacokinetics and Exposure to a Greater Extent Than Renal Function

Clinical therapeutics, 2017-07, Vol.39 (7), p.1360-1370

2017

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Pharmacokinetics and tolerability of single escalating doses of fampridine sustained-release tablets in patients with multiple sclerosis: A phase I–II, open-label trial

Clinical therapeutics, 2009-10, Vol.31 (10), p.2206-2214

2009

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Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-Release 10-mg tablets in patients with multiple sclerosis: A 2-week, open-label, follow-up study

Clinical therapeutics, 2009-10, Vol.31 (10), p.2215-2223

2009

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Ion channel blockers and glioblastoma risk and outcome: a nested case-control and retrospective cohort studies

Pharmacoepidemiology and drug safety, 2016-10, Vol.25 (10), p.1179-1185

2016

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Safety, Patient-Reported Well-Being, and Physician-Reported Assessment of Walking Ability in Patients with Multiple Sclerosis for Prolonged-Release Fampridine Treatment in Routine Clinical Practice: Results of the LIBERATE Study

CNS drugs, 2021-09, Vol.35 (9), p.1009-1022

2021

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Pharmacokinetics of dalfampridine extended release 7.5-mg tablets in healthy subjects and individuals with mild and moderate renal impairment: An open-label study

Journal of clinical pharmacology, 2014-01, Vol.54 (1), p.53-60

2014

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First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors

Investigational new drugs, 2017-06, Vol.35 (3), p.324-333

2017

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Effects of a selective aldosterone blocker and thiazide-type diuretic on blood pressure and organ damage in hypertensive patients

Clinical and experimental hypertension (1993), 2015-10, Vol.37 (7), p.569-573

2015

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Effects of menthol on circular smooth muscle of human colon: Analysis of the mechanism of action

European journal of pharmacology, 2014-10, Vol.740, p.295-301

2014

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Assessment of the efficacy and safety of fampridine

Farmacia Hospitalaria, 2017-03, Vol.41 (2), p.283-291

2017

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Amlodipine and Loop Diuretics as the Second Anti-Hypertensive Medication for the Treatment of Hypertension with Chronic Kidney Diseases

Clinical and experimental hypertension (1993), 2011-07, Vol.33 (4), p.210-215

2011

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Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER

Clinical neuropharmacology, 2016-03, Vol.39 (2), p.73-80

2016

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Single-Dose Pharmacokinetics of Sustained-Release Fampridine (Fampridine-SR) in Healthy Volunteers and Adults With Renal Impairment

Journal of clinical pharmacology, 2010-02, Vol.50 (2), p.151-159

2010

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Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle

European journal of clinical pharmacology, 2006-05, Vol.62 (5), p.347-354

2006

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Relaxation by urocortin of human saphenous veins

British journal of pharmacology, 2002-05, Vol.136 (1), p.90-94

2002

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Intraindividual comparison of human radial and internal thoracic arteries in vitro and the effect of preoperative calcium blocker therapy

Fundamental & clinical pharmacology, 2007-02, Vol.21 (1), p.67-74

2007

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Onset of Hyperkalemia following the Administration of Angiotensin-Converting Enzyme Inhibitor or Angiotensin II Receptor Blocker

Cardiovascular therapeutics, 2021, Vol.2021, p.5935149-8

2021

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Population Pharmacokinetics/Pharmacodynamics of 3,4‐Diaminopyridine Free Base in Patients With Lambert‐Eaton Myasthenia

Pharmacological characterisation of capsaicin-induced relaxations in human and porcine isolated arteries

Calcium channel subtypes contributing to acetylcholine release from normal, 4‐aminopyridine‐treated and myasthenic syndrome auto‐antibodies‐affected neuromuscular junctions

Potassium channel subtypes as molecular targets for overactive bladder and other urological disorders

Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones

Effects of the chromanol HMR 1556 on potassium currents in atrial myocytes

An evaluation of a potential calcium channel blocker–lower-extremity edema–loop diuretic prescribing cascade

Treatment of internuclear ophthalmoparesis in multiple sclerosis with fampridine: A randomized double‐blind, placebo‐controlled cross‐over trial

Acetylator Status Impacts Amifampridine Phosphate (Firdapse™) Pharmacokinetics and Exposure to a Greater Extent Than Renal Function

Pharmacokinetics and tolerability of single escalating doses of fampridine sustained-release tablets in patients with multiple sclerosis: A phase I–II, open-label trial

Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-Release 10-mg tablets in patients with multiple sclerosis: A 2-week, open-label, follow-up study

Ion channel blockers and glioblastoma risk and outcome: a nested case-control and retrospective cohort studies

Safety, Patient-Reported Well-Being, and Physician-Reported Assessment of Walking Ability in Patients with Multiple Sclerosis for Prolonged-Release Fampridine Treatment in Routine Clinical Practice: Results of the LIBERATE Study

Pharmacokinetics of dalfampridine extended release 7.5-mg tablets in healthy subjects and individuals with mild and moderate renal impairment: An open-label study

First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors

Effects of a selective aldosterone blocker and thiazide-type diuretic on blood pressure and organ damage in hypertensive patients

Effects of menthol on circular smooth muscle of human colon: Analysis of the mechanism of action

Assessment of the efficacy and safety of fampridine

Amlodipine and Loop Diuretics as the Second Anti-Hypertensive Medication for the Treatment of Hypertension with Chronic Kidney Diseases

Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER

Single-Dose Pharmacokinetics of Sustained-Release Fampridine (Fampridine-SR) in Healthy Volunteers and Adults With Renal Impairment

Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle

Relaxation by urocortin of human saphenous veins

Intraindividual comparison of human radial and internal thoracic arteries in vitro and the effect of preoperative calcium blocker therapy

Onset of Hyperkalemia following the Administration of Angiotensin-Converting Enzyme Inhibitor or Angiotensin II Receptor Blocker

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