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Structures of the calcium-activated, non-selective cation channel TRPM4

Nature (London), 2017-12, Vol.552 (7684), p.205-209

2017

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Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways

Journal of the American Chemical Society, 2018-06, Vol.140 (24), p.7568-7578

2018

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ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase

Nature (London), 2013-02, Vol.494 (7435), p.121-124

2013

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Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

Antiviral research, 2020-10, Vol.182, p.104899-104899, Article 104899

2020

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Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.4573-4589

2015

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Targeted delivery of adenosine 5′-triphosphate using chitosan-coated mesoporous hydroxyapatite: A theranostic pH-sensitive nanoplatform with enhanced anti-cancer effect

International journal of biological macromolecules, 2019-05, Vol.129, p.1090-1102

2019

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New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens

European journal of medicinal chemistry, 2021-03, Vol.213, p.113200, Article 113200

2021

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Mechanism of Force Generation of a Viral DNA Packaging Motor

Cell, 2005-09, Vol.122 (5), p.683-692

2005

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Mechanism of folding chamber closure in a group II chaperonin

Nature (London), 2010-01, Vol.463 (7279), p.379-383

2010

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Synergy and Antagonism between Allosteric and Active‐Site Inhibitors of Abl Tyrosine Kinase

Angewandte Chemie International Edition, 2021-09, Vol.60 (37), p.20196-20199

International ed. in English, 2021

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Painful purinergic receptors

The Journal of pharmacology and experimental therapeutics, 2008-02, Vol.324 (2), p.409-415

2008

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Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain

Science translational medicine, 2011-01, Vol.3 (65), p.65ra3

2011

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ATP-gated P2X cation-channels

Neuropharmacology, 2009-01, Vol.56 (1), p.208-215

2009

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ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR

Nature chemical biology, 2021-11, Vol.17 (11), p.1148-1156

2021

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Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

European journal of medicinal chemistry, 2022-01, Vol.227, p.113926-113926, Article 113926

2022

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Recent progress towards clinically relevant ATP-competitive Akt inhibitors

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (13), p.2838-2848

2017

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Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors

Bioorganic & medicinal chemistry, 2021-12, Vol.52, p.116514-116514, Article 116514

2021

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Unexpected Effects of K+ and Adenosine Triphosphate on the Thermal Stability of Na+,K+‑ATPase

The journal of physical chemistry. B, 2017-05, Vol.121 (19), p.4949-4957

2017

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A chemical genetic approach to engineer phototropin kinases for substrate labeling

The Journal of biological chemistry, 2018-04, Vol.293 (15), p.5613-5623

2018

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Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound 26 (PKI-587), a Highly Efficacious Dual Inhibitor

Journal of medicinal chemistry, 2010-03, Vol.53 (6), p.2636-2645

2010

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Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists

Biochemical pharmacology, 2016-09, Vol.116, p.130-139

2016

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Nonhydrolyzable ATP Analogues as Selective Inhibitors of Human NPP1: A Combined Computational/Experimental Study

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8308-8320

2013

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Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance

The Journal of biological chemistry, 2003-07, Vol.278 (30), p.27439

2003

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Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors[S]

Journal of lipid research, 2017-06, Vol.58 (6), p.1055-1066

2017

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Drosophila taste neurons as an agonist-screening platform for P2X receptors

Scientific reports, 2020-05, Vol.10 (1), p.8292-8292, Article 8292

2020

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Structures of the calcium-activated, non-selective cation channel TRPM4

Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways

ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase

Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol

Targeted delivery of adenosine 5′-triphosphate using chitosan-coated mesoporous hydroxyapatite: A theranostic pH-sensitive nanoplatform with enhanced anti-cancer effect

New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens

Mechanism of Force Generation of a Viral DNA Packaging Motor

Mechanism of folding chamber closure in a group II chaperonin

Synergy and Antagonism between Allosteric and Active‐Site Inhibitors of Abl Tyrosine Kinase

Painful purinergic receptors

Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain

ATP-gated P2X cation-channels

ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR

Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

Recent progress towards clinically relevant ATP-competitive Akt inhibitors

Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors

Unexpected Effects of K+ and Adenosine Triphosphate on the Thermal Stability of Na+,K+‑ATPase

A chemical genetic approach to engineer phototropin kinases for substrate labeling

Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound 26 (PKI-587), a Highly Efficacious Dual Inhibitor

Structure-based identification and characterisation of structurally novel human P2X7 receptor antagonists

Nonhydrolyzable ATP Analogues as Selective Inhibitors of Human NPP1: A Combined Computational/Experimental Study

Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenance

Surfactant inhibits ATP-induced release of interleukin-1β via nicotinic acetylcholine receptors[S]

Drosophila taste neurons as an agonist-screening platform for P2X receptors

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