UB Paderborn / Katalog / Suche / in CDI

Simple, sensitive, and cost-effective detection of wAlbB Wolbachia in Aedes mosquitoes, using loop mediated isothermal amplification combined with the electrochemical biosensing method

PLoS neglected tropical diseases, 2022-05, Vol.16 (5), p.e0009600-e0009600

2022

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Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (2), p.613-617

2014

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Development and evaluation of an immunochromatographic assay to detect serum anti-leptospiral lipopolysaccharide IgM in acute leptospirosis

Scientific reports, 2017-05, Vol.7 (1), p.2309-9, Article 2309

2017

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Forty-four years of ScienceAsia: from a domestic journal to an international journal

ScienceAsia : journal of the Science Society of Thailand, 2018-02, Vol.44S (1), p.4

Sirawaraporn, Worachart

2018

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Antifolate-Resistant Mutants of Plasmodium falciparum Dihydrofolate Reductase

Proceedings of the National Academy of Sciences - PNAS, 1997-02, Vol.94 (4), p.1124-1129

1997

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Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Antimicrobial Agents and Chemotherapy, 2006-09, Vol.50 (9), p.3132-3141

2006

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Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase

Malaria journal, 2013-03, Vol.12 (1), p.91-91, Article 91

2013

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Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases

Journal of the Royal Society interface, 2015-03, Vol.12 (104), p.20141289

2015

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Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthase

Acta tropica, 2015-09, Vol.149, p.64-69

2015

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Cloning and Expression of Mycobacterium tuberculosis and Mycobacterium leprae Dihydropteroate Synthase in Escherichia coli

Journal of Bacteriology, 1999-11, Vol.181 (21), p.6814-6821

1999

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The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase. Gene synthesis, expression, and anti-folate-resistant mutants

The Journal of biological chemistry, 1993-10, Vol.268 (29), p.21637-21644

1993

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Inhibitors of Multiple Mutants of Plasmodium falciparum Dihydrofolate Reductase and Their Antimalarial Activities

Journal of medicinal chemistry, 2004-01, Vol.47 (3), p.673-680

2004

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Docking and Database Screening Reveal New Classes of Plasmodium falciparum Dihydrofolate Reductase Inhibitors

Journal of medicinal chemistry, 2003-07, Vol.46 (14), p.2834-2845

2003

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Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

Journal of molecular biology, 2000-01, Vol.295 (2), p.307-323

2000

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Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

Malaria journal, 2004-06, Vol.3 (1), p.16-16

2004

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Probing the roles of non-homologous insertions in the N-terminal domain of Plasmodium falciparum hydroxymethylpterin pyrophosphokinase–dihydropteroate synthase

Molecular and biochemical parasitology, 2009-12, Vol.168 (2), p.135-142

2009

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Dihydrofolate reductase and antifolate resistance in malaria

Drug resistance updates, 1998, Vol.1 (6), p.397-406

Sirawaraporn, Worachart

1998

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Development of 2,4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+S108N Mutants of Dihydrofolate Reductase from Pyrimethamine-Resistant Plasmodium falciparum

Journal of medicinal chemistry, 2002-03, Vol.45 (6), p.1244-1252

2002

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Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance

Bioorganic & medicinal chemistry, 2000-05, Vol.8 (5), p.1117-1128

2000

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Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro

Molecular and biochemical parasitology, 2007-07, Vol.154 (1), p.1-5

2007

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Development of a Lead Inhibitor for the A16V+S108T Mutant of Dihydrofolate Reductase from the Cycloguanil-Resistant Strain (T9/94) of Plasmodium falciparum

Journal of medicinal chemistry, 2000-07, Vol.43 (14), p.2738-2744

2000

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Synthesis of Solution-Phase Combinatorial Library of 4,6-Diamino-1,2-dihydro-1,3,5-triazine and Identification of New Leads Against A16V+S108T Mutant Dihydrofolate Reductase of Plasmodium falciparum

Bioorganic & medicinal chemistry, 2003-01, Vol.11 (2), p.217-224

2003

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Use of immunoblotting as an alternative method for serogrouping Leptospira

Journal of medical microbiology, 2007-05, Vol.56 (5), p.587-592

2007

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Pyrimethamine analogs as strong inhibitors of double and quadruple mutants of dihydrofolate reductase in human malaria parasites

Organic & biomolecular chemistry, 2003-03, Vol.1 (6), p.960-964

2003

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Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax

Molecular and biochemical parasitology, 2002, Vol.119 (1), p.63-73

2002

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Simple, sensitive, and cost-effective detection of wAlbB Wolbachia in Aedes mosquitoes, using loop mediated isothermal amplification combined with the electrochemical biosensing method

Design and synthesis of guanylthiourea derivatives as potential inhibitors of Plasmodium falciparum dihydrofolate reductase enzyme

Development and evaluation of an immunochromatographic assay to detect serum anti-leptospiral lipopolysaccharide IgM in acute leptospirosis

Forty-four years of ScienceAsia: from a domestic journal to an international journal

Antifolate-Resistant Mutants of Plasmodium falciparum Dihydrofolate Reductase

Eosin B as a Novel Antimalarial Agent for Drug-Resistant Plasmodium falciparum

Insights into the role of the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase

Cheaper faster drug development validated by the repositioning of drugs against neglected tropical diseases

Use of bacterial surrogates as a tool to explore antimalarial drug interaction: Synergism between inhibitors of malarial dihydrofolate reductase and dihydropteroate synthase

Cloning and Expression of Mycobacterium tuberculosis and Mycobacterium leprae Dihydropteroate Synthase in Escherichia coli

The dihydrofolate reductase domain of Plasmodium falciparum thymidylate synthase-dihydrofolate reductase. Gene synthesis, expression, and anti-folate-resistant mutants

Inhibitors of Multiple Mutants of Plasmodium falciparum Dihydrofolate Reductase and Their Antimalarial Activities

Docking and Database Screening Reveal New Classes of Plasmodium falciparum Dihydrofolate Reductase Inhibitors

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

Probing the roles of non-homologous insertions in the N-terminal domain of Plasmodium falciparum hydroxymethylpterin pyrophosphokinase–dihydropteroate synthase

Dihydrofolate reductase and antifolate resistance in malaria

Development of 2,4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+S108N Mutants of Dihydrofolate Reductase from Pyrimethamine-Resistant Plasmodium falciparum

Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: Structural basis of antifolate resistance

Pyrimethamine-resistant dihydrofolate reductase enzymes of Plasmodium falciparum are not enzymatically compromised in vitro

Development of a Lead Inhibitor for the A16V+S108T Mutant of Dihydrofolate Reductase from the Cycloguanil-Resistant Strain (T9/94) of Plasmodium falciparum

Synthesis of Solution-Phase Combinatorial Library of 4,6-Diamino-1,2-dihydro-1,3,5-triazine and Identification of New Leads Against A16V+S108T Mutant Dihydrofolate Reductase of Plasmodium falciparum

Use of immunoblotting as an alternative method for serogrouping Leptospira

Pyrimethamine analogs as strong inhibitors of double and quadruple mutants of dihydrofolate reductase in human malaria parasites

Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax

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