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Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

American Journal of Physiology: Cell Physiology, 2018-09, Vol.315 (3), p.C343-C356

2018

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Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

Frontiers in physiology, 2020-08, Vol.11, p.914

2020

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Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke

Current pharmaceutical design, 2012-08, Vol.18 (25), p.3624-3644

2012

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Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?

Current pharmaceutical design, 2014-03, Vol.20 (10), p.1422-1449

2014

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Distribution of insulin in trigeminal nerve and brain after intranasal administration

Scientific reports, 2019-02, Vol.9 (1), p.2621-2621, Article 2621

2019

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Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

The AAPS journal, 2017-07, Vol.19 (4), p.910-920

2017

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Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery?

The AAPS journal, 2017-07, Vol.19 (4), p.931-939

2017

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Candesartan restores blood–brain barrier dysfunction, mitigates aberrant gene expression, and extends lifespan in a knockin mouse model of epileptogenesis

Clinical science (1979), 2024-09, Vol.138 (17), p.1089-1110

2024

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Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke

International journal of molecular sciences, 2022-02, Vol.23 (3), p.1898

2022

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Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Pharmaceutics, 2022-07, Vol.14 (7), p.1501

2022

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Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

Clinical science (1979), 2024-02, Vol.138 (4), p.205-223

2024

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HIV‐1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein‐1 (Mrp1) in glial cells

Journal of neurochemistry, 2008-08, Vol.106 (3), p.1298-1313

2008

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HIV-1 Viral Envelope Glycoprotein gp120 Triggers an Inflammatory Response in Cultured Rat Astrocytes and Regulates the Functional Expression of P-Glycoprotein

Molecular pharmacology, 2006-09, Vol.70 (3), p.1087-1098

2006

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In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain

The journal of histochemistry and cytochemistry, 2006-10, Vol.54 (10), p.1159-1167

2006

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Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats

Fluids and barriers of the CNS, 2018-09, Vol.15 (1), p.25-25, Article 25

2018

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Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Pharmaceutics, 2020-02, Vol.12 (2), p.154

2020

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Hypoxia/Reoxygenation Stress Signals an Increase in Organic Anion Transporting polypeptide 1a4 (Oatp1a4) at the Blood–Brain Barrier: Relevance to CNS Drug Delivery

Journal of cerebral blood flow and metabolism, 2014-04, Vol.34 (4), p.699-707

2014

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P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia

Journal of neurochemistry, 2012-09, Vol.122 (5), p.962-975

2012

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Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism

Molecular pharmacology, 2013-11, Vol.84 (5), p.774-786

2013

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Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke

Journal of Central Nervous System Disease, 2017-04, Vol.2017 (9), p.1179573517693802-1179573517693802

2017

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P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac

PloS one, 2014-02, Vol.9 (2), p.e88516

2014

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Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity

Pharmaceutics, 2018-10, Vol.10 (4), p.192

2018

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Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

Journal of neuroscience research, 2009-03, Vol.87 (4), p.1023-1036

2009

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Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier

The Journal of pharmacology and experimental therapeutics, 2011-03, Vol.336 (3), p.827-839

2011

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High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats

Pharmaceutics, 2022-04, Vol.14 (5), p.949

2022

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Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke

Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?

Distribution of insulin in trigeminal nerve and brain after intranasal administration

Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery?

Candesartan restores blood–brain barrier dysfunction, mitigates aberrant gene expression, and extends lifespan in a knockin mouse model of epileptogenesis

Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke

Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

HIV‐1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein‐1 (Mrp1) in glial cells

HIV-1 Viral Envelope Glycoprotein gp120 Triggers an Inflammatory Response in Cultured Rat Astrocytes and Regulates the Functional Expression of P-Glycoprotein

In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain

Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats

Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Hypoxia/Reoxygenation Stress Signals an Increase in Organic Anion Transporting polypeptide 1a4 (Oatp1a4) at the Blood–Brain Barrier: Relevance to CNS Drug Delivery

P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia

Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism

Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke

P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac

Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier

High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats

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