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Schistosomiasis control: praziquantel forever?

Molecular and biochemical parasitology, 2014-06, Vol.195 (1), p.23-29

2014

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Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment

International journal for parasitology, 2004-03, Vol.34 (4), p.527-533

2004

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Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

Science (American Association for the Advancement of Science), 2013-12, Vol.342 (6164), p.1385-1389

2013

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Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

PLoS neglected tropical diseases, 2015-10, Vol.9 (10), p.e0004132-e0004132

2015

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The schistosome enzyme that activates oxamniquine has the characteristics of a sulfotransferase

Memórias do Instituto Oswaldo Cruz, 2006-10, Vol.101 Suppl 1 (suppl 1), p.307-312

2006

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Praziquantel

Parasitology research (1987), 2003-06, Vol.90 (S1), p.S3-S9

2003

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Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance

Expert review of anti-infective therapy, 2006-04, Vol.4 (2), p.199-210

2006

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Schistosoma mansoni: Lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death

Experimental parasitology, 2008-07, Vol.119 (3), p.332-335

2008

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Effect of praziquantel on the immature stages of Schistosoma haematobium

International journal for parasitology, 2005-11, Vol.35 (13), p.1453-1457

2005

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Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates

International journal for parasitology, 2004-07, Vol.34 (8), p.979-987

2004

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Antischistosomal drugs: Past, present … and future?

Pharmacology & therapeutics (Oxford), 1995, Vol.68 (1), p.35-85

1995

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Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy

The Journal of biological chemistry, 2017-07, Vol.292 (27), p.11154-11164

2017

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Cytochalasin D abolishes the schistosomicidal activity of praziquantel

Experimental parasitology, 2007-04, Vol.115 (4), p.344-351

2007

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Decades down the line: the viability of praziquantel for future schistosomiasis treatment

Expert review of anti-infective therapy, 2012-08, Vol.10 (8), p.835-837

2012

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Synthesis of new praziquantel analogues: Potential candidates for the treatment of schistosomiasis

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (2), p.1103-1106

2012

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Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni

Acta tropica, 2009-07, Vol.111 (1), p.82-85

2009

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Schistosoma mansoni: Hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene

Experimental parasitology, 1992-12, Vol.75 (4), p.425-432

1992

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Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

PLoS neglected tropical diseases, 2016-06, Vol.9 (10)

2016

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Sequence and level of endogenous expression of calcium channel β subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel

Molecular and biochemical parasitology, 2003-08, Vol.130 (2), p.111-115

2003

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Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine: e0004132

PLoS neglected tropical diseases, 2015-10, Vol.9 (10)

2015

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Praziquantel derivatives I: Modification of the aromatic ring

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4154-4157

2007

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The preparation, antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone

Journal of medicinal chemistry, 1988-01, Vol.31 (1), p.254-260

1988

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Synthesis and biological properties of some 6H-pyrido[4,3-b]carbazoles

Journal of medicinal chemistry, 1987-07, Vol.30 (7), p.1204-1210

1987

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Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality

Molecular and biochemical parasitology, 2002-11, Vol.125 (1), p.1-9

2002

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Is actin the praziquantel receptor?

International journal of antimicrobial agents, 2007-09, Vol.30 (3), p.280-281

2007

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Schistosoma Mansoni - Drug Effects
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Parasitology
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Biological And Medical Sciences
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Drug Resistance
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Praziquantel
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Humans
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Hycanthone - Pharmacology
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Antibiotics. Antiinfectious Agents. Antiparasitic Agents
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Oxamniquine - Pharmacology
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Schistosomiasis control: praziquantel forever?

Sex- and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment

Genetic and Molecular Basis of Drug Resistance and Species-Specific Drug Action in Schistosome Parasites

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

The schistosome enzyme that activates oxamniquine has the characteristics of a sulfotransferase

Praziquantel

Praziquantel for the treatment of schistosomiasis: its use for control in areas with endemic disease and prospects for drug resistance

Schistosoma mansoni: Lack of correlation between praziquantel-induced intra-worm calcium influx and parasite death

Effect of praziquantel on the immature stages of Schistosoma haematobium

Determination of ED50 values for praziquantel in praziquantel-resistant and -susceptible Schistosoma mansoni isolates

Antischistosomal drugs: Past, present … and future?

Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy

Cytochalasin D abolishes the schistosomicidal activity of praziquantel

Decades down the line: the viability of praziquantel for future schistosomiasis treatment

Synthesis of new praziquantel analogues: Potential candidates for the treatment of schistosomiasis

Genetic analysis of decreased praziquantel sensitivity in a laboratory strain of Schistosoma mansoni

Schistosoma mansoni: Hycanthone/oxamniquine resistance is controlled by a single autosomal recessive gene

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine

Sequence and level of endogenous expression of calcium channel β subunits in Schistosoma mansoni displaying different susceptibilities to praziquantel

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine: e0004132

Praziquantel derivatives I: Modification of the aromatic ring

The preparation, antischistosomal and antitumor activity of hycanthone and some of its congeners. Evidence for the mode of action of hycanthone

Synthesis and biological properties of some 6H-pyrido[4,3-b]carbazoles

Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality

Is actin the praziquantel receptor?

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