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Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [ 11 C]PHNO PET

Neuropsychopharmacology (New York, N.Y.), 2022-06, Vol.47 (7), p.1405-1412

2022

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Pharmacokinetics and ADME Characterization of Intravenous and Oral [ 14 C]-Linerixibat in Healthy Male Volunteers

Drug metabolism and disposition, 2021-12, Vol.49 (12), p.1109-1117

2021

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ONO‐7684 a novel oral FXIa inhibitor: Safety, tolerability, pharmacokinetics and pharmacodynamics in a first‐in‐human study

British journal of clinical pharmacology, 2021-08, Vol.87 (8), p.3177-3189

2021

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Safety and immunogenicity of a two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Europe (EBOVAC2): a randomised, observer-blind, participant-blind, placebo-controlled, phase 2 trial

The Lancet infectious diseases, 2021-04, Vol.21 (4), p.493-506

2021

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Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials

The Lancet (British edition), 2024-02, Vol.403 (10428), p.741-755

2024

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Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects

British journal of clinical pharmacology, 2021-10, Vol.87 (10), p.3949-3960

2021

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2831. Efficacy and Safety of Gepotidacin for Uncomplicated Urinary Tract Infection: Pooled Subgroup Analyses of the EAGLE-2 and EAGLE-3 Randomized Phase 3 Trials

Open forum infectious diseases, 2023-11, Vol.10 (Supplement_2)

2023

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A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study

Antimicrobial agents and chemotherapy, 2020-04, Vol.64 (5)

2020

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2832. Gepotidacin Efficacy in E. coli Drug-Resistant Phenotypes: A Pooled Analysis of the EAGLE-2 and EAGLE-3 Randomized Controlled Trials in Uncomplicated Urinary Tract Infection

Open forum infectious diseases, 2023-11, Vol.10 (Supplement_2)

2023

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2837. Impact of Regulatory Guidelines on Therapeutic, Clinical, and Microbiological Success Rates in Uncomplicated Urinary Tract Infection: Results from a Two Phase 3 Randomized Controlled Trials of Oral Gepotidacin (EAGLE-2 and EAGLE-3)

Open forum infectious diseases, 2023-11, Vol.10 (Supplement_2)

2023

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Amenamevir: Studies of Potential CYP2C8‐ and CYP2B6‐Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers

Clinical pharmacology in drug development, 2018-11, Vol.7 (8), p.860-870

2018

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Amenamevir: Studies of Potential CYP3A‐Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers

Clinical pharmacology in drug development, 2018-11, Vol.7 (8), p.844-859

2018

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P31 Efficacy and safety of oral gepotidacin in the treatment of uncomplicated urinary tract infection: results of two randomized, multicentre Phase 3 trials (EAGLE-2 and EAGLE-3)

JAC-antimicrobial resistance, 2023-08, Vol.5 (Supplement_3)

2023

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Processing of pro‐tumor necrosis factor‐α by venom metalloproteinases: A hypothesis explaining local tissue damage following snake bite

European journal of immunology, 1996-09, Vol.26 (9), p.2000-2005

1996

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The British Society for Antimicrobial Chemotherapy Resistance Surveillance Project: a successful collaborative model

Journal of antimicrobial chemotherapy, 2008-11, Vol.62 (suppl-2), p.ii3-ii14

White, Anthony R

2008

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Long-term nutrient reductions lead to the unprecedented recovery of a temperate coastal region

Proceedings of the National Academy of Sciences - PNAS, 2018-04, Vol.115 (14), p.3658-3662

2018

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Ecological Forecasting and the Science of Hypoxia in Chesapeake Bay

Bioscience, 2017-07, Vol.67 (7), p.614-626

2017

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Rise of Ruppia in Chesapeake Bay: Climate change-driven turnover of foundation species creates new threats and management opportunities

Proceedings of the National Academy of Sciences - PNAS, 2023-06, Vol.120 (23), p.e2220678120-e2220678120

2023

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Abstract 1534 Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106677, Article 106677

2024

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Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift

Nature communications, 2022-05, Vol.13 (1), p.2460-2460, Article 2460

2022

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Methanobactin and the Link between Copper and Bacterial Methane Oxidation

Microbiology and molecular biology reviews, 2016-06, Vol.80 (2), p.387-409

2016

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Submersed Aquatic Vegetation in Chesapeake Bay: Sentinel Species in a Changing World

Bioscience, 2017-08, Vol.67 (8), p.698-712

2017

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Data synthesis for environmental management: A case study of Chesapeake Bay

Journal of environmental management, 2022-11, Vol.321, p.115901-115901, Article 115901

2022

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Long-term Annual Aerial Surveys of Submersed Aquatic Vegetation (SAV) Support Science, Management, and Restoration

Estuaries and coasts, 2022-06, Vol.45 (4), p.1012-1027

2022

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Real-Time Ultrasound Imaging of the Tear Trough: Lessons Learned From Functional Anatomy

Aesthetic surgery journal, 2022-04, Vol.42 (5), p.518-526

2022

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Endogenous dopamine release in the human brain as a pharmacodynamic biomarker: evaluation of the new GPR139 agonist TAK-041 with [ 11 C]PHNO PET

Pharmacokinetics and ADME Characterization of Intravenous and Oral [ 14 C]-Linerixibat in Healthy Male Volunteers

ONO‐7684 a novel oral FXIa inhibitor: Safety, tolerability, pharmacokinetics and pharmacodynamics in a first‐in‐human study

Safety and immunogenicity of a two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Europe (EBOVAC2): a randomised, observer-blind, participant-blind, placebo-controlled, phase 2 trial

Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials

Safety, tolerability and pharmacokinetics of emodepside, a potential novel treatment for onchocerciasis (river blindness), in healthy male subjects

2831. Efficacy and Safety of Gepotidacin for Uncomplicated Urinary Tract Infection: Pooled Subgroup Analyses of the EAGLE-2 and EAGLE-3 Randomized Phase 3 Trials

A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study

2832. Gepotidacin Efficacy in E. coli Drug-Resistant Phenotypes: A Pooled Analysis of the EAGLE-2 and EAGLE-3 Randomized Controlled Trials in Uncomplicated Urinary Tract Infection

2837. Impact of Regulatory Guidelines on Therapeutic, Clinical, and Microbiological Success Rates in Uncomplicated Urinary Tract Infection: Results from a Two Phase 3 Randomized Controlled Trials of Oral Gepotidacin (EAGLE-2 and EAGLE-3)

Amenamevir: Studies of Potential CYP2C8‐ and CYP2B6‐Mediated Pharmacokinetic Interactions With Montelukast and Bupropion in Healthy Volunteers

Amenamevir: Studies of Potential CYP3A‐Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers

P31 Efficacy and safety of oral gepotidacin in the treatment of uncomplicated urinary tract infection: results of two randomized, multicentre Phase 3 trials (EAGLE-2 and EAGLE-3)

Processing of pro‐tumor necrosis factor‐α by venom metalloproteinases: A hypothesis explaining local tissue damage following snake bite

The British Society for Antimicrobial Chemotherapy Resistance Surveillance Project: a successful collaborative model

Long-term nutrient reductions lead to the unprecedented recovery of a temperate coastal region

Ecological Forecasting and the Science of Hypoxia in Chesapeake Bay

Rise of Ruppia in Chesapeake Bay: Climate change-driven turnover of foundation species creates new threats and management opportunities

Abstract 1534 Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift

Methanobactin and the Link between Copper and Bacterial Methane Oxidation

Submersed Aquatic Vegetation in Chesapeake Bay: Sentinel Species in a Changing World

Data synthesis for environmental management: A case study of Chesapeake Bay

Long-term Annual Aerial Surveys of Submersed Aquatic Vegetation (SAV) Support Science, Management, and Restoration

Real-Time Ultrasound Imaging of the Tear Trough: Lessons Learned From Functional Anatomy

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