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Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors

European journal of medicinal chemistry, 2017-07, Vol.135, p.174-195

2017

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Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane‐ or Cycloheptane‐Annulated 1,5‐Benzothiazepine Scaffold

Chemistry : a European journal, 2017-01, Vol.23 (1), p.128-136

2017

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Exploration of thiaheterocyclic hHDAC6 inhibitors as potential antiplasmodial agents

Future medicinal chemistry, 2017-03, Vol.9 (4), p.357-364

2017

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Engineering the specificity of trehalose phosphorylase as a general strategy for the production of glycosyl phosphates

Chemical communications (Cambridge, England), 2014-07, Vol.50 (58), p.7834-7836

2014

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N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis

Beilstein journal of organic chemistry, 2012-03, Vol.8 (1), p.398-402

2012

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Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models

International journal of cancer, 2019-08, Vol.145 (3), p.735-747

2019

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Converting bulk sugars into prebiotics: semi-rational design of a transglucosylase with controlled selectivity

Chemical communications (Cambridge, England), 2016-03, Vol.52 (18), p.3687-3689

2016

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Synthesis and biological assessment of novel N-(hydroxy/methoxy)alkyl β-enaminone curcuminoids

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (23), p.5650-5656

2016

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Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A

Chemical communications (Cambridge, England), 2013-05, Vol.49 (36), p.3775-3777

2013

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Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

Chemical communications (Cambridge, England), 2015-06, Vol.51 (48), p.9868-9871

2015

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Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress

European journal of medicinal chemistry, 2016-11, Vol.123, p.727-736

2016

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Design, Synthesis, and Antiviral Evaluation of Purine-β-lactam and Purine-aminopropanol Hybrids

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5637-5641

2012

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Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors

Organic & biomolecular chemistry, 2016-01, Vol.14 (8), p.2537-2549

2016

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Converting bulk sugars into prebiotics: semi-rational design of a transglucosylase with controlled selectivityElectronic supplementary information (ESI) available: Mutagenesis, screening, ProSAR modelling, ligand docking, product analysis, production and downstream processing. See DOI: 10.1039/c5cc09940d

2016-02

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Synthesis of bis-8-hydroxyquinolines via an imination or a Suzuki-Miyaura coupling approach

Tetrahedron letters, 2017-10, Vol.58 (40), p.3803-3807

2017

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Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin AElectronic supplementary information (ESI) available: Synthetic procedures and spectral data of compounds 3, 4, 5, 6, 7 and 8, and bioassay results. See DOI: 10.1039/c3cc41422a

2013-04

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Engineering the specificity of trehalose phosphorylase as a general strategy for the production of glycosyl phosphatesElectronic supplementary information (ESI) available: Methods and supporting data. See DOI: 10.1039/c4cc02202e

2014-06

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Exploration of Thiaheterocyclic H Hdac6 Inhibitors as Potential Antiplasmodial Agents

Future medicinal chemistry, 2017-03, Vol.9 (4), p.357-364

2017

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Exploration of thiaheterocyclic

Future medicinal chemistry, 2017-03, Vol.9 (4), p.357-364

2017

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Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition

MedChemComm, 2018-06, Vol.9 (6), p.1011-1016

2018

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Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00107c

MedChemComm, 2018-05, Vol.9 (6), p.1011-1016

2018

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Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitorsElectronic supplementary information (ESI) available: Synthetic procedures, spectral data, bioassay results, ligand docking data. See DOI: 10.1039/c5cc03295d

2015-06

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Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors

Synthesis of Potent and Selective HDAC6 Inhibitors Bearing a Cyclohexane‐ or Cycloheptane‐Annulated 1,5‐Benzothiazepine Scaffold

Exploration of thiaheterocyclic hHDAC6 inhibitors as potential antiplasmodial agents

Engineering the specificity of trehalose phosphorylase as a general strategy for the production of glycosyl phosphates

N-Heterocyclic carbene/Brønsted acid cooperative catalysis as a powerful tool in organic synthesis

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models

Converting bulk sugars into prebiotics: semi-rational design of a transglucosylase with controlled selectivity

Synthesis and biological assessment of novel N-(hydroxy/methoxy)alkyl β-enaminone curcuminoids

Potent and selective HDAC6 inhibitory activity of N-(4-hydroxycarbamoylbenzyl)-1,2,4,9-tetrahydro-3-thia-9-azafluorenes as novel sulfur analogues of Tubastatin A

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitors

Synthesis of novel curcuminoids accommodating a central β-enaminone motif and their impact on cell growth and oxidative stress

Design, Synthesis, and Antiviral Evaluation of Purine-β-lactam and Purine-aminopropanol Hybrids

Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors

Synthesis of bis-8-hydroxyquinolines via an imination or a Suzuki-Miyaura coupling approach

Engineering the specificity of trehalose phosphorylase as a general strategy for the production of glycosyl phosphatesElectronic supplementary information (ESI) available: Methods and supporting data. See DOI: 10.1039/c4cc02202e

Exploration of Thiaheterocyclic H Hdac6 Inhibitors as Potential Antiplasmodial Agents

Exploration of thiaheterocyclic

Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition

Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00107c

Synthesis of benzothiophene-based hydroxamic acids as potent and selective HDAC6 inhibitorsElectronic supplementary information (ESI) available: Synthetic procedures, spectral data, bioassay results, ligand docking data. See DOI: 10.1039/c5cc03295d

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