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A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice

Science translational medicine, 2012-11, Vol.4 (159), p.159ra147

2012

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TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury

American journal of physiology. Lung cellular and molecular physiology, 2014-07, Vol.307 (2), p.L158-L172

2014

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N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I

The Journal of pharmacology and experimental therapeutics, 2008-08, Vol.326 (2), p.432

2008

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Overactive Bladder and Incontinence in the Absence of the BK Large Conductance Ca2+-activated K+ Channel

The Journal of biological chemistry, 2004-08, Vol.279 (35), p.36746-36752

2004

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Enhanced sensitivity to afferent stimulation and impact of overactive bladder therapies in the conscious, spontaneously hypertensive rat

The Journal of pharmacology and experimental therapeutics, 2011-07, Vol.338 (1), p.392

2011

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Ion channels in smooth muscle: regulators of intracellular calcium and contractility

Canadian journal of physiology and pharmacology, 2005-03, Vol.83 (3), p.215

2005

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Enhanced bladder capacity and reduced prostaglandin E2-mediated bladder hyperactivity in EP3 receptor knockout mice

American journal of physiology. Renal physiology, 2008-08, Vol.295 (2), p.F507

2008

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Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current

The Journal of physiology, 2003-05, Vol.549 (1), p.65-74

2003

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Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells

Channels (Austin, Tex.), 2009-05, Vol.3 (3), p.156-160

2009

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Properties of a tonically active, sodium-permeable current in mouse urinary bladder smooth muscle

American Journal of Physiology: Cell Physiology, 2004-06, Vol.286 (6), p.C1246-C1257

2004

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Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo

The Journal of pharmacology and experimental therapeutics, 2021-03, Vol.376 (3), p.436

2021

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Heteromultimeric Kv1.2-Kv1.5 Channels Underlie 4-Aminopyridine-Sensitive Delayed Rectifier K+ Current of Rabbit Vascular Myocytes

Circulation research, 2001-11, Vol.89 (11), p.1038-1044

2001

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The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction

Neuroscience letters, 2009-03, Vol.452 (1), p.28-32

2009

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Voltage-gated Na+ Channel Blockers Reduce Functional Bladder Capacity in the Conscious Spontaneously Hypertensive Rat

Urology (Ridgewood, N.J.), 2012-06, Vol.79 (6), p.1410.e1-1410.e6

2012

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Effect of Estrogen and Progesterone on Urodynamics in the Conscious Rat

Urology (Ridgewood, N.J.), 2009-08, Vol.74 (2), p.463-466

2009

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Urodynamic Measurements by Radiotelemetry in Conscious, Freely Moving Beagle Dogs

The Journal of urology, 2009-03, Vol.181 (3), p.1444-1451

2009

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Molecular Composition of 4-Aminopyridine-Sensitive Voltage-Gated K+ Channels of Vascular Smooth Muscle

Circulation research, 2001-11, Vol.89 (11), p.1030-1037

2001

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Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2

The Journal of pharmacology and experimental therapeutics, 2008-08, Vol.326 (2), p.443

2008

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Heteromultimeric Kv1 Channels Contribute to Myogenic Control of Arterial Diameter

Circulation research, 2005-02, Vol.96 (2), p.216-224

2005

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Differential expression of fos and jun family members during murine postnatal intestinal development

Biology of the neonate, 1996, Vol.69 (5), p.342

1996

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A human disease model of drug toxicity-induced pulmonary edema in a lung-on-a-chip microdevice

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

Overactive Bladder and Incontinence in the Absence of the BK Large Conductance Ca2+-activated K+ Channel

Enhanced sensitivity to afferent stimulation and impact of overactive bladder therapies in the conscious, spontaneously hypertensive rat

Ion channels in smooth muscle: regulators of intracellular calcium and contractility

Enhanced bladder capacity and reduced prostaglandin E2-mediated bladder hyperactivity in EP3 receptor knockout mice

Properties and molecular basis of the mouse urinary bladder voltage-gated K+ current

Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells

Properties of a tonically active, sodium-permeable current in mouse urinary bladder smooth muscle

Identification of a Human Whole Blood-Based Endothelial Cell Impedance Assay for Assessing Clinical Transient Receptor Potential Vanilloid 4 Target Engagement Ex Vivo

Heteromultimeric Kv1.2-Kv1.5 Channels Underlie 4-Aminopyridine-Sensitive Delayed Rectifier K+ Current of Rabbit Vascular Myocytes

The voltage-gated sodium channel Nav1.9 is required for inflammation-based urinary bladder dysfunction

Voltage-gated Na+ Channel Blockers Reduce Functional Bladder Capacity in the Conscious Spontaneously Hypertensive Rat

Effect of Estrogen and Progesterone on Urodynamics in the Conscious Rat

Urodynamic Measurements by Radiotelemetry in Conscious, Freely Moving Beagle Dogs

Molecular Composition of 4-Aminopyridine-Sensitive Voltage-Gated K+ Channels of Vascular Smooth Muscle

Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2

Heteromultimeric Kv1 Channels Contribute to Myogenic Control of Arterial Diameter

Differential expression of fos and jun family members during murine postnatal intestinal development

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