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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

PLoS pathogens, 2024-05, Vol.20 (5), p.e1012198-e1012198

2024

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Development of innate and adaptive immunity to RSV in young children

Cellular immunology, 2024-05, Vol.399-400, p.104824-104824, Article 104824

2024

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Mucosal immunization with a low-energy electron inactivated respiratory syncytial virus vaccine protects mice without Th2 immune bias

Frontiers in immunology, 2024, Vol.15, p.1382318-1382318

2024

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A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Nature communications, 2015-09, Vol.6 (1), p.8143-8143, Article 8143

2015

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Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection

Journal of virology, 2014-04, Vol.88 (8), p.4237-4250

2014

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Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Vaccine, 2016-09, Vol.34 (42), p.5114-5124

2016

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Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy

The New England journal of medicine, 2022-04, Vol.386 (17), p.1615-1626

2022

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Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies

PloS one, 2014, Vol.9 (6), p.e100392

2014

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Immunology of bovine respiratory syncytial virus in calves

Molecular immunology, 2015-07, Vol.66 (1), p.48-56

2015

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Recombinant bovine respiratory syncytial virus with deletion of the SH gene induces increased apoptosis and pro-inflammatory cytokines in vitro, and is attenuated and induces protective immunity in calves

Journal of general virology, 2014-06, Vol.95 (Pt 6), p.1244-1254

2014

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Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Nature communications, 2019-10, Vol.10 (1), p.4595-18

2019

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Novel antigens for RSV vaccines

Current opinion in immunology, 2015-08, Vol.35, p.30-38

2015

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Brief History and Characterization of Enhanced Respiratory Syncytial Virus Disease

Clinical and vaccine immunology, 2016-03, Vol.23 (3), p.189-195

2016

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Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children

The Journal of infectious diseases, 2020-06, Vol.221 (12), p.2050-2059

2020

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The role of Th17 and Treg responses in the pathogenesis of RSV infection

Pediatric research, 2015-11, Vol.78 (5), p.483-491

2015

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Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

Immunological reviews, 2011-01, Vol.239 (1), p.149-166

Graham, Barney S.

2011

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Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

Nature (London), 2013-09, Vol.501 (7467), p.439-443

2013

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A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice

Vaccine, 2017-02, Vol.35 (5), p.757-766

2017

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Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates

Cell host & microbe, 2022-01, Vol.30 (1), p.41-52.e5

2022

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Immunopathology of RSV: An Updated Review

Viruses, 2021-12, Vol.13 (12), p.2478

2021

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Safety and Immunogenicity of Bivalent RSVpreF Vaccine Coadministered With Seasonal Inactivated Influenza Vaccine in Older Adults

Clinical infectious diseases, 2024-05, Vol.78 (5), p.1360-1368

2024

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Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.6-13

2016

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Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

Nature communications, 2018-05, Vol.9 (1), p.1904-10, Article 1904

2018

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Vaccination against respiratory syncytial virus in pregnancy: a suitable tool to combat global infant morbidity and mortality?

The Lancet infectious diseases, 2016-08, Vol.16 (8), p.e153-e163

2016

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Progress toward a Respiratory Syncytial Virus Vaccine

Clinical and vaccine immunology, 2016-03, Vol.23 (3), p.186-188

2016

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Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters

Development of innate and adaptive immunity to RSV in young children

Mucosal immunization with a low-energy electron inactivated respiratory syncytial virus vaccine protects mice without Th2 immune bias

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism

Chimeric bovine/human parainfluenza virus type 3 expressing respiratory syncytial virus (RSV) F glycoprotein: effect of insert position on expression, replication, immunogenicity, stability, and protection against RSV infection

Formulation of the respiratory syncytial virus fusion protein with a polymer-based combination adjuvant promotes transient and local innate immune responses and leads to improved adaptive immunity

Prefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy

Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies

Immunology of bovine respiratory syncytial virus in calves

Recombinant bovine respiratory syncytial virus with deletion of the SH gene induces increased apoptosis and pro-inflammatory cytokines in vitro, and is attenuated and induces protective immunity in calves

Viral N 6 -methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus

Novel antigens for RSV vaccines

Brief History and Characterization of Enhanced Respiratory Syncytial Virus Disease

Live-Attenuated Respiratory Syncytial Virus Vaccine With M2-2 Deletion and With Small Hydrophobic Noncoding Region Is Highly Immunogenic in Children

The role of Th17 and Treg responses in the pathogenesis of RSV infection

Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

A single, low dose of a cGMP recombinant BCG vaccine elicits protective T cell immunity against the human respiratory syncytial virus infection and prevents lung pathology in mice

Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates

Immunopathology of RSV: An Updated Review

Safety and Immunogenicity of Bivalent RSVpreF Vaccine Coadministered With Seasonal Inactivated Influenza Vaccine in Older Adults

Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection

Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model

Vaccination against respiratory syncytial virus in pregnancy: a suitable tool to combat global infant morbidity and mortality?

Progress toward a Respiratory Syncytial Virus Vaccine

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