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Ferns and Lycopods—A Potential Treasury of Anticancer Agents but Also a Carcinogenic Hazard

Phytotherapy research, 2014-06, Vol.28 (6), p.798-810

Tomsik, Pavel

2014

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Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to In Vivo Studies

Journal of medicinal chemistry, 2020-05, Vol.63 (10), p.5568-5584

2020

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The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice

Biomedicine & pharmacotherapy, 2017-11, Vol.95, p.828-836

2017

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Chlorambucil conjugates of dinuclear p-cymene ruthenium trithiolato complexes: synthesis, characterization and cytotoxicity study in vitro and in vivo

Journal of biological inorganic chemistry, 2016-07, Vol.21 (4), p.443-452

2016

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Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013-10, Vol.936, p.48-56

2013

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In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [(η6-p-MeC6H4Pri)2Ru2(μ-S-p-C6H4OH)3]Cl

Anti-cancer drugs, 2016-08, Vol.27 (7), p.643-650

2016

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[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study

Journal of organometallic chemistry, 2015-04, Vol.782, p.42-51

2015

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In vivo effect of oracin on doxorubicin reduction, biodistribution and efficacy in Ehrlich tumor bearing mice

Pharmacological reports, 2013, Vol.65 (2), p.445-452

2013

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Anticancer potential of Amaryllidaceae alkaloids evaluated by screening with a panel of human cells, real-time cellular analysis and Ehrlich tumor-bearing mice

Chemico-biological interactions, 2017-09, Vol.275, p.121-132

2017

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Relation between Sustainability-Related Communication and Competitiveness in the Chemical Industry

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2017, Vol.65 (1), p.283-292

2017

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Boldine and Related Aporphines: From Antioxidant to Antiproliferative Properties

Natural product communications, 2013-12, Vol.8 (12), p.1797-1800

2013

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The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction

Oncology reports, 2013-12, Vol.30 (6), p.2593-2602

2013

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Analysis of attractiveness of the wine-production industry in the Czech Republic

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015-06, Vol.52 (3), p.135-142

2015

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Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity

Bioorganic chemistry, 2019-02, Vol.82, p.204-210

2019

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Analysis and proposal of solution of company employees rewarding

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015-06, Vol.52 (3), p.51-58

2015

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In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [([eta]6-p-MeC6H4Pri)2Ru2( mu -S-p-C6H4OH)3]Cl

Anti-cancer drugs, 2016-08, Vol.27 (7), p.643-650

2016

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Boldine enhances bile production in rats via osmotic and Farnesoid X receptor dependent mechanisms

Toxicology and applied pharmacology, 2015-05, Vol.285 (1), p.12-22

2015

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Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2

Toxicology (Amsterdam), 2013-01, Vol.303 (7), p.9-15

2013

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Attractiveness of Czech winegrowing and wine-production in the stage of adaptation to the united market of the European Union

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2014-12, Vol.54 (3), p.101-114

2014

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The anticancer activity of alpha-tomatine against mammary adenocarcinoma in mice

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, 2013-06, Vol.157 (2), p.153-161

2013

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How Does Implementation of Environmental Management System Contribute to Corporate Sustainability Management

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2014, Vol.62 (6), p.1499-1508

2014

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Pravastatin modulates liver bile acid and cholesterol homeostasis in rats with chronic cholestasis

Journal of gastroenterology and hepatology, 2011-10, Vol.26 (10), p.1544-1551

2011

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Increasing competitiveness of wine producers in strategic alliances VOC

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012, Vol.60 (2), p.293-298

2012

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Increased melibiose/rhamnose ratio in bile of rats with acute cholestasis

Journal of gastroenterology and hepatology, 2008-12, Vol.23 (12), p.1934-1940

2008

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Evaluation of the antineoplastic activity of L-rhamnose in vitro. A comparison with 2-deoxyglucose

Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove, 2008, Vol.51 (2), p.113-119

2008

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Animals
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Pharmacology & Pharmacy
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Cell Proliferation - Drug Effects
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Mice
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Rats
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Alkaloids
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Biochemistry & Molecular Biology
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Cancer
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Cell Line, Tumor
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Rats, Wistar
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Ferns and Lycopods—A Potential Treasury of Anticancer Agents but Also a Carcinogenic Hazard

Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as a Potential Chemotherapeutic Agent: From Synthesis to In Vivo Studies

The effects of β-caryophyllene oxide and trans-nerolidol on the efficacy of doxorubicin in breast cancer cells and breast tumor-bearing mice

Chlorambucil conjugates of dinuclear p-cymene ruthenium trithiolato complexes: synthesis, characterization and cytotoxicity study in vitro and in vivo

Development of an HPLC fluorescence method for determination of boldine in plasma, bile and urine of rats and identification of its major metabolites by LC–MS/MS

In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [(η6-p-MeC6H4Pri)2Ru2(μ-S-p-C6H4OH)3]Cl

[(p-MeC6H4Pr )2Ru2(SC6H4-p-Bu )3]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study

In vivo effect of oracin on doxorubicin reduction, biodistribution and efficacy in Ehrlich tumor bearing mice

Anticancer potential of Amaryllidaceae alkaloids evaluated by screening with a panel of human cells, real-time cellular analysis and Ehrlich tumor-bearing mice

Relation between Sustainability-Related Communication and Competitiveness in the Chemical Industry

Boldine and Related Aporphines: From Antioxidant to Antiproliferative Properties

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction

Analysis of attractiveness of the wine-production industry in the Czech Republic

Novel quinazolin-4-one derivatives as potentiating agents of doxorubicin cytotoxicity

Analysis and proposal of solution of company employees rewarding

In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [([eta]6-p-MeC6H4Pri)2Ru2( mu -S-p-C6H4OH)3]Cl

Boldine enhances bile production in rats via osmotic and Farnesoid X receptor dependent mechanisms

Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2

Attractiveness of Czech winegrowing and wine-production in the stage of adaptation to the united market of the European Union

The anticancer activity of alpha-tomatine against mammary adenocarcinoma in mice

How Does Implementation of Environmental Management System Contribute to Corporate Sustainability Management

Pravastatin modulates liver bile acid and cholesterol homeostasis in rats with chronic cholestasis

Increasing competitiveness of wine producers in strategic alliances VOC

Increased melibiose/rhamnose ratio in bile of rats with acute cholestasis

Evaluation of the antineoplastic activity of L-rhamnose in vitro. A comparison with 2-deoxyglucose

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