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Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis

Molecular metabolism (Germany), 2017-09, Vol.6 (9), p.943-957

2017

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Oxidative Stress, Antioxidants and Hypertension

Antioxidants, 2023-01, Vol.12 (2), p.281

2023

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Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis

Cell reports (Cambridge), 2020-04, Vol.31 (1), p.107469-107469, Article 107469

2020

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Mouse pancreas tissue slice culture facilitates long-term studies of exocrine and endocrine cell physiology in situ

PloS one, 2013-11, Vol.8 (11), p.e78706-e78706

2013

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Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function

Nature communications, 2022-10, Vol.13 (1), p.6255-6255, Article 6255

2022

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Mast cells acquire MHCII from dendritic cells during skin inflammation

The Journal of experimental medicine, 2017-12, Vol.214 (12), p.3791-3811

2017

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Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters

Scientific reports, 2024-08, Vol.14 (1), p.19863-16

2024

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Long-term culture of human pancreatic slices as a model to study real-time islet regeneration

Nature communications, 2020-06, Vol.11 (1), p.3265-3265, Article 3265

2020

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Noninvasive Monitoring of Glycemia-Induced Regulation of GLP-1R Expression in Murine and Human Islets of Langerhans

Diabetes (New York, N.Y.), 2020-11, Vol.69 (11), p.2246-2252

2020

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Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21456-21461

2012

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Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics

Diabetes (New York, N.Y.), 2007-04, Vol.56 (4), p.1078-1086

2007

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Reporter islets in the eye reveal the plasticity of the endocrine pancreas

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (51), p.20581-20586

2013

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Impaired islet function and normal exocrine enzyme secretion occur with low inter-regional variation in type 1 diabetes

Cell reports (Cambridge), 2024-06, Vol.43 (6), p.114346-114346, Article 114346

2024

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Donor Islet Endothelial Cells in Pancreatic Islet Revascularization

Diabetes (New York, N.Y.), 2011-10, Vol.60 (10), p.2571-2577

2011

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Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

Nature protocols, 2008-08, Vol.3 (8), p.1278-1286

2008

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Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice

Diabetologia, 2015-10, Vol.59 (1), p.139-150

2015

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The biomechanical properties of an epithelial tissue determine the location of its vasculature

Nature communications, 2016-12, Vol.7 (1), p.13560-13560, Article 13560

2016

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Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis

JCI insight, 2020-04, Vol.5 (8)

2020

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Publisher Correction: Long-term culture of human pancreatic slices as a model to study real-time islet regeneration

Nature communications, 2020-07, Vol.11 (1), p.3742-3742, Article 3742

2020

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Mechanism of pro-MMP9 activation in co-culture of pro-inflammatory macrophages and cardiomyocytes

Experimental cell research, 2024-01, Vol.434 (1), p.113868-113868, Article 113868

2024

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Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity

Diabetologia, 2018-01, Vol.61 (1), p.182-192

2018

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Experimental Approaches for High-Resolution In Vivo Imaging of Islet of Langerhans Biology

Current diabetes reports, 2011-10, Vol.11 (5), p.420-425

Speier, Stephan

2011

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Alterations in β-Cell Calcium Dynamics and Efficacy Outweigh Islet Mass Adaptation in Compensation of Insulin Resistance and Prediabetes Onset

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2676-2685

2016

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Mast Cell Promotion of T Cell–Driven Antigen‐Induced Arthritis Despite Being Dispensable for Antibody‐Induced Arthritis in Which T Cells Are Bypassed

Arthritis & rheumatology (Hoboken, N.J.), 2015-04, Vol.67 (4), p.903-913

2015

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Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis

Oxidative Stress, Antioxidants and Hypertension

Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis

Mouse pancreas tissue slice culture facilitates long-term studies of exocrine and endocrine cell physiology in situ

Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function

Mast cells acquire MHCII from dendritic cells during skin inflammation

Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters

Long-term culture of human pancreatic slices as a model to study real-time islet regeneration

Noninvasive Monitoring of Glycemia-Induced Regulation of GLP-1R Expression in Murine and Human Islets of Langerhans

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

Cx36-Mediated Coupling Reduces β-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics

Reporter islets in the eye reveal the plasticity of the endocrine pancreas

Impaired islet function and normal exocrine enzyme secretion occur with low inter-regional variation in type 1 diabetes

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization

Noninvasive high-resolution in vivo imaging of cell biology in the anterior chamber of the mouse eye

Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice

The biomechanical properties of an epithelial tissue determine the location of its vasculature

Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis

Publisher Correction: Long-term culture of human pancreatic slices as a model to study real-time islet regeneration

Mechanism of pro-MMP9 activation in co-culture of pro-inflammatory macrophages and cardiomyocytes

Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity

Experimental Approaches for High-Resolution In Vivo Imaging of Islet of Langerhans Biology

Alterations in β-Cell Calcium Dynamics and Efficacy Outweigh Islet Mass Adaptation in Compensation of Insulin Resistance and Prediabetes Onset

Mast Cell Promotion of T Cell–Driven Antigen‐Induced Arthritis Despite Being Dispensable for Antibody‐Induced Arthritis in Which T Cells Are Bypassed

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