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Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity

Cancer research (Chicago, Ill.), 2013-11, Vol.73 (22), p.6780-6792

2013

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Abstract P5-08-06: Differential effects of eribulin on key transcription factors snail and slug

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.P5-P5-08-06

2019

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Abstract P5-04-04: Eribulin differentially disrupts TGF-β signaling pathway in BT-549 and HCC1937 breast cancer cell lines

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.P5-P5-04-04

2018

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Abstract P4-04-04: Eribulin impairs TGF-β type I receptor localization and signaling in BT-549 cells

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P4-P4-04-04

2017

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Abstract P2-13-01: Differential efficacies of DNA damaging agents in basal-like TNBC subtypes

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.P2-P2-13-01

2018

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Abstract P5-03-08: Eribulin impairs the transport of TGF-β type I receptor leading to inhibition of downstream non-canonical TGF-β signaling necessary for cancer metastasis and survival

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-03-08

2016

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Abstract P6-13-07: The taccalonolides are novel microtubule stabilizers that covalently bind tubulin and have in vivo efficacy in drug resistant tumors

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P6-P6-13-07

2016

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Abstract P5-03-04: Identification of compounds from natural sources with selective activity against triple-negative breast cancer molecular subtypes

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-03-04

2016

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Abstract P5-03-09: Eribulin affects E-cadherin localization consistent with a reversal of the epithelial-to-mesenchymal transition

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-03-09

2016

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Abstract P1-15-07: The neuroprotective aminopropyl carbazole, P7C3-A20, prevents paclitaxel-induced pain

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P1-P1-15-07

2016

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Abstract P5-04-18: Extracts derived from fungi and plants demonstrate specificity for subtyptes of triple negative breast cancer

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-04-18

2016

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P3-16-17: The Identification of Novel Microtubule Stabilizing Taccalonolides

Cancer research (Chicago, Ill.), 2011-12, Vol.71 (24_Supplement), p.P3-P3-16-17

2011

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The taccalonolides are a novel class of microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Cancer research (Chicago, Ill.), 2009-01, Vol.69 (2_Supplement), p.2142

2009

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Mapping chromatin structure in vivo using DNA methyltransferases

Methods (San Diego, Calif.), 2004-05, Vol.33 (1), p.68-80

2004

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Microtubule-Targeting Drugs: More than Antimitotics

Journal of natural products (Washington, D.C.), 2019-03, Vol.82 (3), p.680-685

2019

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Eribulin mesylate: mechanism of action of a unique microtubule-targeting agent

Clinical cancer research, 2015-06, Vol.21 (11), p.2445-2452

2015

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Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility

Oncogene, 2013-07, Vol.32 (27), p.3246-3253

2013

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Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis

PLoS genetics, 2021-12, Vol.17 (12), p.e1009986-e1009986

2021

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Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products

Natural product reports, 2020-05, Vol.37 (5), p.634-652

2020

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NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana

PLoS genetics, 2016-09, Vol.12 (9), p.e1006333-e1006333

2016

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Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (9), p.1-11

2021

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Efficacy of a Covalent Microtubule Stabilizer in Taxane-Resistant Ovarian Cancer Models

Molecules (Basel, Switzerland), 2021-07, Vol.26 (13), p.4077

2021

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Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner

British journal of cancer, 2019-10, Vol.121 (7), p.611-621

2019

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Elucidating target specificity of the taccalonolide covalent microtubule stabilizers employing a combinatorial chemical approach

Nature communications, 2020-01, Vol.11 (1), p.654-13, Article 654

2020

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Analysis of gene duplication within the Arabidopsis NUCLEAR FACTOR Y, subunit B (NF-YB) protein family reveals domains under both purifying and diversifying selection

PloS one, 2023-08, Vol.18 (8), p.e0289332-e0289332

2023

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Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity

Abstract P5-08-06: Differential effects of eribulin on key transcription factors snail and slug

Abstract P5-04-04: Eribulin differentially disrupts TGF-β signaling pathway in BT-549 and HCC1937 breast cancer cell lines

Abstract P4-04-04: Eribulin impairs TGF-β type I receptor localization and signaling in BT-549 cells

Abstract P2-13-01: Differential efficacies of DNA damaging agents in basal-like TNBC subtypes

Abstract P5-03-08: Eribulin impairs the transport of TGF-β type I receptor leading to inhibition of downstream non-canonical TGF-β signaling necessary for cancer metastasis and survival

Abstract P6-13-07: The taccalonolides are novel microtubule stabilizers that covalently bind tubulin and have in vivo efficacy in drug resistant tumors

Abstract P5-03-04: Identification of compounds from natural sources with selective activity against triple-negative breast cancer molecular subtypes

Abstract P5-03-09: Eribulin affects E-cadherin localization consistent with a reversal of the epithelial-to-mesenchymal transition

Abstract P1-15-07: The neuroprotective aminopropyl carbazole, P7C3-A20, prevents paclitaxel-induced pain

Abstract P5-04-18: Extracts derived from fungi and plants demonstrate specificity for subtyptes of triple negative breast cancer

P3-16-17: The Identification of Novel Microtubule Stabilizing Taccalonolides

The taccalonolides are a novel class of microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Mapping chromatin structure in vivo using DNA methyltransferases

Microtubule-Targeting Drugs: More than Antimitotics

Eribulin mesylate: mechanism of action of a unique microtubule-targeting agent

Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility

Co-existing TP53 and ARID1A mutations promote aggressive endometrial tumorigenesis

Targeting and extending the eukaryotic druggable genome with natural products: cytoskeletal targets of natural products

NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana

Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site

Efficacy of a Covalent Microtubule Stabilizer in Taxane-Resistant Ovarian Cancer Models

Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner

Elucidating target specificity of the taccalonolide covalent microtubule stabilizers employing a combinatorial chemical approach

Analysis of gene duplication within the Arabidopsis NUCLEAR FACTOR Y, subunit B (NF-YB) protein family reveals domains under both purifying and diversifying selection

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