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HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis

Leukemia, 2002-04, Vol.16 (4), p.508-519

2002

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Targeting tumor cell metabolism with statins

Oncogene, 2012-11, Vol.31 (48), p.4967-4978

2012

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Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells

Leukemia, 2001-09, Vol.15 (9), p.1398-1407

2001

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New model systems provide insights into Myc-induced transformation

Oncogene, 2011-08, Vol.30 (34), p.3727-3734

2011

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MYC activity is negatively regulated by a C-terminal lysine cluster

Oncogene, 2014-02, Vol.33 (8), p.1066-1072

2014

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Cerivastatin Triggers Tumor-specific Apoptosis with Higher Efficacy than Lovastatin

Clinical cancer research, 2001-07, Vol.7 (7), p.2067-2075

2001

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Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria

Molecular and Cellular Biology, 2001-07, Vol.21 (14), p.4725-4736

2001

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Lysine-52 stabilizes the MYC oncoprotein through an SCFFbxw7-independent mechanism

Oncogene, 2017-12, Vol.36 (49), p.6815-6822

2017

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Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types

The EMBO journal, 1996-08, Vol.15 (16), p.4130-4141

1996

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Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents

Oncogene, 1998-10, Vol.17 (17), p.2149-2154

1998

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Induction of apoptosis in fibroblasts by c-myc protein

Cell, 1992-04, Vol.69 (1), p.119-128

1992

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Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase

Biochemical journal, 2000-11, Vol.352 Pt 1 (Pt 1), p.135-143

2000

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Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro

Cancer research (Chicago, Ill.), 1995-05, Vol.55 (9), p.1982-1988

1995

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Myc represses the growth arrest gene gadd45

Oncogene, 1997-06, Vol.14 (23), p.2825-2834

1997

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The molecular role of Myc in growth and transformation: recent discoveries lead to new insights

The FASEB journal, 1998-06, Vol.12 (9), p.633-651

1998

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The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter

Molecular and Cellular Biology, 1997-01, Vol.17 (1), p.100-114

1997

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Lovastatin Induces a Pronounced Differentiation Response in Acute Myeloid Leukemias

Leukemia & lymphoma, 2000, Vol.40 (1-2), p.167-178

2000

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Lovastatin Induced Control of Blast Cell Growth in an Elderly Patient with Acute Myeloblastic Leukemia

Leukemia & lymphoma, 2001, Vol.40 (5-6), p.659-662

2001

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Myc Is an Essential Negative Regulator of Platelet-Derived Growth Factor Beta Receptor Expression

Molecular and Cellular Biology, 2000-09, Vol.20 (18), p.6768-6778

2000

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Increased Sensitivity of Acute Myeloid Leukemias to Lovastatin-Induced Apoptosis: A Potential Therapeutic Approach

Blood, 1999-02, Vol.93 (4), p.1308-1318

1999

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Analysis of Myc Bound Loci Identified by CpG Island Arrays Shows that Max Is Essential for Myc-Dependent Repression

Current biology, 2003-05, Vol.13 (10), p.882-886

2003

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Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

Oncogene, 1999-06, Vol.18 (23), p.3520-3528

1999

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Repression of the human immunodeficiency virus type-1 long terminal repeat by the c-Myc oncoprotein

Journal of cellular biochemistry, 2004-05, Vol.92 (2), p.400-413

2004

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Promotion of growth and apoptosis in c-myc nullizygous fibroblasts by other members of the myc oncoprotein family

Cell death and differentiation, 2000-08, Vol.7 (8), p.697-705

2000

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Differential Sensitivity of Various Pediatric Cancers and Squamous Cell Carcinomas to Lovastatin-induced Apoptosis: Therapeutic Implications

Clinical cancer research, 2001-01, Vol.7 (1), p.158-167

2001

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HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis

Targeting tumor cell metabolism with statins

Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells

New model systems provide insights into Myc-induced transformation

MYC activity is negatively regulated by a C-terminal lysine cluster

Cerivastatin Triggers Tumor-specific Apoptosis with Higher Efficacy than Lovastatin

Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria

Lysine-52 stabilizes the MYC oncoprotein through an SCFFbxw7-independent mechanism

Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types

Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents

Induction of apoptosis in fibroblasts by c-myc protein

Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase

Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro

Myc represses the growth arrest gene gadd45

The molecular role of Myc in growth and transformation: recent discoveries lead to new insights

The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter

Lovastatin Induces a Pronounced Differentiation Response in Acute Myeloid Leukemias

Lovastatin Induced Control of Blast Cell Growth in an Elderly Patient with Acute Myeloblastic Leukemia

Myc Is an Essential Negative Regulator of Platelet-Derived Growth Factor Beta Receptor Expression

Increased Sensitivity of Acute Myeloid Leukemias to Lovastatin-Induced Apoptosis: A Potential Therapeutic Approach

Analysis of Myc Bound Loci Identified by CpG Island Arrays Shows that Max Is Essential for Myc-Dependent Repression

Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts

Repression of the human immunodeficiency virus type-1 long terminal repeat by the c-Myc oncoprotein

Promotion of growth and apoptosis in c-myc nullizygous fibroblasts by other members of the myc oncoprotein family

Differential Sensitivity of Various Pediatric Cancers and Squamous Cell Carcinomas to Lovastatin-induced Apoptosis: Therapeutic Implications

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