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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

Annual review of nutrition, 2016-07, Vol.36 (1), p.275-299

2016

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Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice

Journal of lipid research, 2018-09, Vol.59 (9), p.1714-1728

2018

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Antiatherogenic properties of flavonoids: Implications for cardiovascular health

Canadian journal of cardiology, 2010-03, Vol.26, p.17A-21A

2010

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Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor–Null Mice With Diet-Induced Insulin Resistance

Diabetes (New York, N.Y.), 2009-10, Vol.58 (10), p.2198-2210

2009

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The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S]

Journal of lipid research, 2020-03, Vol.61 (3), p.387-402

2020

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Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Journal of lipid research, 2013-03, Vol.54 (3), p.711-724

2013

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Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21

Endocrinology (Philadelphia), 2015-06, Vol.156 (6), p.2087-2102

2015

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Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

Gastroenterology (New York, N.Y. 1943), 2009-11, Vol.137 (5), p.1795-1804

2009

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PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

Journal of lipid research, 2014-07, Vol.55 (7), p.1254-1266

2014

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ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia

Current opinion in lipidology, 2017-04, Vol.28 (2), p.193-200

2017

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Citrus flavonoids and lipid metabolism

Current opinion in lipidology, 2013-02, Vol.24 (1), p.34-40

2013

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molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin

Journal of lipid research, 2007-03, Vol.48 (3), p.699-708

2007

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Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol

The Journal of biological chemistry, 2007-02, Vol.282 (8), p.5207-5216

2007

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Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes

Diabetes (New York, N.Y.), 2005-06, Vol.54 (6), p.1676-1683

2005

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Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells

Circulation research, 2009-04, Vol.104 (7), p.832-841

2009

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Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player

Current opinion in lipidology, 2013-04, Vol.24 (2), p.171-177

2013

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Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

PPAR Research, 2012-01, Vol.2012, p.857142-9

2012

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Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

Journal of lipid research, 2001-05, Vol.42 (5), p.725-734

2001

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Apolipoprotein C-III: Going Back to the Future for a Lipid Drug Target

Circulation research, 2013-05, Vol.112 (11), p.1405-1408

2013

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Inhibition of Net HepG2 Cell Apolipoprotein B Secretion by the Citrus Flavonoid Naringenin Involves Activation of Phosphatidylinositol 3-Kinase, Independent of Insulin Receptor Substrate-1 Phosphorylation

Diabetes (New York, N.Y.), 2003-10, Vol.52 (10), p.2554-2561

2003

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Regression of atherosclerosis: lessons learned from genetically modified mouse models

Current opinion in lipidology, 2018-04, Vol.29 (2), p.87-94

2018

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Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

Journal of lipid research, 2008-10, Vol.49 (10), p.2218-2229

2008

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Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

Cardiovascular diabetology, 2008-03, Vol.7 (1), p.5-5, Article 5

2008

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Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Lean, Pair‐Fed Ldlr−/− Mice

Molecular nutrition & food research, 2019-03, Vol.63 (6), p.e1800833-n/a

2019

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Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

Biochemical journal, 2002-09, Vol.366 (Pt 2), p.531-539

2002

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Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis

Intervention with citrus flavonoids reverses obesity and improves metabolic syndrome and atherosclerosis in obese Ldlr−/− mice

Antiatherogenic properties of flavonoids: Implications for cardiovascular health

Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor–Null Mice With Diet-Induced Insulin Resistance

The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK[S]

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr−/− mice[S]

Naringenin Prevents Obesity, Hepatic Steatosis, and Glucose Intolerance in Male Mice Independent of Fibroblast Growth Factor 21

Fibroblast Growth Factor 21 Reduces the Severity of Cerulein-Induced Pancreatitis in Mice

PPARδ activation attenuates hepatic steatosis in Ldlr−/− mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity

ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia

Citrus flavonoids and lipid metabolism

molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin

Selective Up-regulation of LXR-regulated Genes ABCA1, ABCG1, and APOE in Macrophages through Increased Endogenous Synthesis of 24(S),25-Epoxycholesterol

Inhibition of Microsomal Triglyceride Transfer Protein Expression and Apolipoprotein B100 Secretion by the Citrus Flavonoid Naringenin and by Insulin Involves Activation of the Mitogen-Activated Protein Kinase Pathway in Hepatocytes

Lipid Incorporation Inhibits Src-Dependent Assembly of Fibronectin and Type I Collagen by Vascular Smooth Muscle Cells

Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player

Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation

Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP

Apolipoprotein C-III: Going Back to the Future for a Lipid Drug Target

Inhibition of Net HepG2 Cell Apolipoprotein B Secretion by the Citrus Flavonoid Naringenin Involves Activation of Phosphatidylinositol 3-Kinase, Independent of Insulin Receptor Substrate-1 Phosphorylation

Regression of atherosclerosis: lessons learned from genetically modified mouse models

Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor

Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Lean, Pair‐Fed Ldlr−/− Mice

Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms

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