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Myeloproliferative neoplasms: from origins to outcomes

Blood, 2017-12, Vol.130 (23), p.2475-2483

2017

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Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Cell stem cell, 2015-06, Vol.16 (6), p.712-724

2015

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Janus Kinase Deregulation in Leukemia and Lymphoma

Immunity (Cambridge, Mass.), 2012-04, Vol.36 (4), p.529-541

2012

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Effect of Mutation Order on Myeloproliferative Neoplasms

The New England journal of medicine, 2015-02, Vol.372 (7), p.601-612

2015

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A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

Cancer cell, 2013-08, Vol.24 (2), p.167-181

2013

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Notch Signaling Mediates Secondary Senescence

Cell reports (Cambridge), 2019-04, Vol.27 (4), p.997-1007.e5

2019

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Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

Developmental cell, 2011-05, Vol.20 (5), p.597-609

2011

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JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Blood, 2013-11, Vol.122 (23), p.3787-3797

2013

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Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (35), p.13081-13086

2008

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Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion

PLoS biology, 2013-06, Vol.11 (6), p.e1001576

2013

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Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm

Blood, 2010-04, Vol.115 (14), p.2891-2900

2010

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MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort

Blood, 2008-07, Vol.112 (1), p.141-149

2008

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JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Blood, 2010-09, Vol.116 (9), p.1528-1538

2010

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Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment

Cell reports (Cambridge), 2017-05, Vol.19 (8), p.1503-1511

2017

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JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease

Blood, 2014-05, Vol.123 (20), p.3139-3151

2014

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Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes

Blood, 2008-01, Vol.111 (1), p.60-70

2008

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Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Blood, 2018-08, Vol.132 (8), p.791-803

2018

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Guideline for the diagnosis and management of myelofibrosis

British journal of haematology, 2012-08, Vol.158 (4), p.453-471

2012

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Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study

The Lancet (British edition), 2005-12, Vol.366 (9501), p.1945-1953

2005

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How I treat essential thrombocythemia

Blood, 2011-02, Vol.117 (5), p.1472-1482

2011

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Mouse models of myeloproliferative neoplasms: JAK of all grades

Disease models & mechanisms, 2011-05, Vol.4 (3), p.311-317

2011

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Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (45), p.17692-17697

2007

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JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15190-15195

2014

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Reticulin Accumulation in Essential Thrombocythemia: Prognostic Significance and Relationship to Therapy

Journal of clinical oncology, 2009-06, Vol.27 (18), p.2991-2999

2009

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Molecular diagnosis of the myeloproliferative neoplasms: UK guidelines for the detection of JAK2 V617F and other relevant mutations

British journal of haematology, 2013-01, Vol.160 (1), p.25-34

2013

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Geprüft (Peer-Review)
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Science & Technology
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Life Sciences & Biomedicine
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Humans
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Hematology
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Animals
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Biological And Medical Sciences
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Medical Sciences
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Mice
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Hematologic And Hematopoietic Diseases
(64)
Mutation
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Leukemias. Malignant Lymphomas. Malignant Reticulosis. Myelofibrosis
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Female
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Janus Kinase 2 - Genetics
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Male
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Cell Biology
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Myeloproliferative Disorders - Genetics
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Middle Aged
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Proto-Oncogene Proteins - Genetics
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Polycythemia Vera - Genetics
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Base Sequence
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Myeloproliferative neoplasms: from origins to outcomes

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Janus Kinase Deregulation in Leukemia and Lymphoma

Effect of Mutation Order on Myeloproliferative Neoplasms

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis

Notch Signaling Mediates Secondary Senescence

Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion

Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm

MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease

Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Guideline for the diagnosis and management of myelofibrosis

Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study

How I treat essential thrombocythemia

Mouse models of myeloproliferative neoplasms: JAK of all grades

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

Reticulin Accumulation in Essential Thrombocythemia: Prognostic Significance and Relationship to Therapy

Molecular diagnosis of the myeloproliferative neoplasms: UK guidelines for the detection of JAK2 V617F and other relevant mutations

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