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Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions

Toxicology in vitro, 2003-02, Vol.17 (1), p.93-105

2003

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Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure

Xenobiotica, 2003-03, Vol.33 (3), p.239-254

2003

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Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102 : structural studies on specific CYP2D6 substrate metabolism

Xenobiotica, 1997-04, Vol.27 (4), p.319-339

1997

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A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro

Xenobiotica, 1999-03, Vol.29 (3), p.269-279

OGG, M. S.

1999

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Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme–substrate interactions and QSARs for binding affinity and inhibition

Toxicology in vitro, 2003-04, Vol.17 (2), p.179-190

2003

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Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity

Toxicology (Amsterdam), 1999-03, Vol.133 (1), p.1-33

1999

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Molecular modelling of CYP3A4 from an alignment with CYP102: Identification of key interactions between putative active site residues and CYP3A-specific chemicals

Xenobiotica, 1996-10, Vol.26 (10), p.1067-1086

1996

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Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate

Chemico-biological interactions, 1998-10, Vol.115 (3), p.175-199

1998

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Molecular modelling of the human glucocorticoid receptor (hGR) ligand-binding domain (LBD) by homology with the human estrogen receptor α (hERα) LBD: quantitative structure–activity relationships within a series of CYP3A4 inducers where induction is mediated via hGR involvement

The Journal of steroid biochemistry and molecular biology, 2002-10, Vol.82 (2), p.195-199

2002

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Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform

Xenobiotica, 2000, Vol.30 (1), p.1-25

2000

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Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

Xenobiotica, 1998-03, Vol.28 (3), p.235-268

1998

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Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102

Toxicology (Amsterdam), 1999-11, Vol.139 (1), p.53-79

1999

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Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

Xenobiotica, 1999, Vol.29 (4), p.361-393

1999

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Can Greener Technology Sustain Downstream Processing in Novel Food Bioprocessing by Elimination of Reactive Oxygen Species?

Food and bioproducts processing, 2005, Vol.83 (1), p.68-69

2005

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Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

Xenobiotica, 2004-06, Vol.34 (6), p.549-569

2004

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Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems

Xenobiotica, 2001, Vol.31 (6), p.321-343

2001

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Primary cell-culture of the digestive gland of the marine mussel Mytilus edulis : a time-course study of antioxidant- and biotransformation-enzyme activity and ultrastructural changes

Marine biology, 1999-10, Vol.135 (1), p.65-75

1999

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Isolation and expression of a cDNA coding for rat kidney cytosolic cysteine conjugate beta-lyase

Molecular pharmacology, 1993-05, Vol.43 (5), p.660-665

1993

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Enzyme effects and metabolism of fenitrothion in primary cell culture of the red swamp crayfish Procambarus clarkii

Marine environmental research, 1998-07, Vol.46 (1-5), p.375-378

1998

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Characterisation of biotransformation enzyme activities and DNA integrity in isolated cells of the digestive gland of the common mussel, Mytilus edulis L

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 1998-05, Vol.120 (1), p.51-56

1998

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Characterization of the presence and seasonal variation of a CYP1A-like enzyme in digestive gland of the common mussel, Mytilus edulis

Marine environmental research, 1996, Vol.42 (1), p.297-301

1996

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Mutation analysis of the human CYP3A4 gene 5′ regulatory region: population screening using non-radioactive SSCP

Mutation research, 2002-03, Vol.500 (1), p.103-110

2002

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Environmental oestrogen-mimics display liposomal membrane-antioxidant ability: Importance of molecular modelling predictions

Journal of chemical technology and biotechnology (1986), 1998-10, Vol.73 (2), p.131-136

1998

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Are food and environmental toxicants 'overdetected' by bioassay?

Trends in biotechnology (Regular ed.), 2002-01, Vol.20 (1), p.13-15

2002

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Developmental modulation of cysteine conjugate beta-lyase/glutamine transaminase K/kynurenine aminotransferase mRNA in rat brain

European journal of drug metabolism and pharmacokinetics, 1997-10, Vol.22 (4), p.335-339

1997

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Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions

Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure

Molecular modelling of cytochrome P4502D6 (CYP2D6) based on an alignment with CYP102 : structural studies on specific CYP2D6 substrate metabolism

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro

Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme–substrate interactions and QSARs for binding affinity and inhibition

Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity

Molecular modelling of CYP3A4 from an alignment with CYP102: Identification of key interactions between putative active site residues and CYP3A-specific chemicals

Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate

Molecular modelling of the human glucocorticoid receptor (hGR) ligand-binding domain (LBD) by homology with the human estrogen receptor α (hERα) LBD: quantitative structure–activity relationships within a series of CYP3A4 inducers where induction is mediated via hGR involvement

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102

Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

Can Greener Technology Sustain Downstream Processing in Novel Food Bioprocessing by Elimination of Reactive Oxygen Species?

Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

Carbamazepine: a 'blind' assessment of CYP-associated metabolism and interactions in human liver-derived in vitro systems

Primary cell-culture of the digestive gland of the marine mussel Mytilus edulis : a time-course study of antioxidant- and biotransformation-enzyme activity and ultrastructural changes

Isolation and expression of a cDNA coding for rat kidney cytosolic cysteine conjugate beta-lyase

Enzyme effects and metabolism of fenitrothion in primary cell culture of the red swamp crayfish Procambarus clarkii

Characterisation of biotransformation enzyme activities and DNA integrity in isolated cells of the digestive gland of the common mussel, Mytilus edulis L

Characterization of the presence and seasonal variation of a CYP1A-like enzyme in digestive gland of the common mussel, Mytilus edulis

Mutation analysis of the human CYP3A4 gene 5′ regulatory region: population screening using non-radioactive SSCP

Environmental oestrogen-mimics display liposomal membrane-antioxidant ability: Importance of molecular modelling predictions

Are food and environmental toxicants 'overdetected' by bioassay?

Developmental modulation of cysteine conjugate beta-lyase/glutamine transaminase K/kynurenine aminotransferase mRNA in rat brain

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