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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

International journal of molecular sciences, 2019-01, Vol.20 (1), p.81

2019

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ATP-binding cassette transporter A1: From metabolism to neurodegeneration

Neurobiology of disease, 2014-12, Vol.72, p.13-21

2014

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Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease

Neurobiology of disease, 2021-11, Vol.159, p.105481-105481, Article 105481

2021

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Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease

Nature communications, 2021-06, Vol.12 (1), p.3416-18, Article 3416

2021

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Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12550

2023

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Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

Molecular neurodegeneration, 2020-07, Vol.15 (1), p.41-21, Article 41

2020

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APOEε4 and risk of Alzheimer's disease - time to move forward

Frontiers in neuroscience, 2023-05, Vol.17, p.1195724-1195724

2023

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The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2010-08, Vol.1801 (8), p.824-830

2010

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Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

PloS one, 2013-02, Vol.8 (2), p.e53478

2013

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Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury

Neurobiology of disease, 2017-09, Vol.105, p.1-14

2017

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Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice

Scientific reports, 2017-06, Vol.7 (1), p.4307-13, Article 4307

2017

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Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

The Journal of neuroscience, 2010-05, Vol.30 (20), p.6862-6872

2010

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APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

Alzheimer's research & therapy, 2019-12, Vol.11 (1), p.113-16, Article 113

2019

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RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment

Neurobiology of disease, 2015-10, Vol.82, p.132-140

2015

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Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration

Neurobiology of disease, 2014-03, Vol.63, p.107-114

2014

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Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

PloS one, 2017-02, Vol.12 (2), p.e0172161-e0172161

2017

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Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

Toxicology reports, 2022-01, Vol.9, p.393-403

2022

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Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease

British journal of pharmacology, 2019-09, Vol.176 (18), p.3599-3610

2019

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ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

Acta neuropathologica communications, 2018-07, Vol.6 (1), p.69-13, Article 69

2018

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Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Biochemical pharmacology, 2010-05, Vol.79 (9), p.1310-1316

2010

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Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

The Journal of neuroscience, 2012-09, Vol.32 (38), p.13125-13136

2012

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Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

The Journal of biological chemistry, 2010-11, Vol.285 (47), p.36945-36957

2010

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RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

Scientific reports, 2016-04, Vol.6 (1), p.24048-24048, Article 24048

2016

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Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Science (American Association for the Advancement of Science), 2013-05, Vol.340 (6135), p.924-924

2013

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Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity

The Journal of neuroscience, 2015-08, Vol.35 (34), p.11862-11876

2015

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The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives

ATP-binding cassette transporter A1: From metabolism to neurodegeneration

Small nucleolar RNAs in plasma extracellular vesicles and their discriminatory power as diagnostic biomarkers of Alzheimer's disease

Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease

Extracellular Vesicles in Young Serum Contribute to the Restoration of Age-Related Brain Transcriptomes and Cognition in Old Mice

Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice

APOEε4 and risk of Alzheimer's disease - time to move forward

The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration

Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic

Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury

Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer's model mice

Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment

Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration

Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

Genome-wide alteration of histone methylation profiles associated with cognitive changes in response to developmental arsenic exposure in mice

Therapeutic targeting of nuclear receptors, liver X and retinoid X receptors, for Alzheimer's disease

ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice

Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"

Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity

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