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Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives

Journal of cellular physiology, 2001-04, Vol.187 (1), p.22-36

2001

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Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation

European journal of cancer (1990), 2000-08, Vol.36 (13), p.1649-1660

2000

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Hypoxia-Inducible Factor-1 Modulates Gene Expression in Solid Tumors and Influences Both Angiogenesis and Tumor Growth

Proceedings of the National Academy of Sciences - PNAS, 1997-07, Vol.94 (15), p.8104-8109

1997

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From bench to bedside for gene-directed enzyme prodrug therapy of cancer

Anti-cancer drugs, 2005-04, Vol.16 (4), p.349-359

2005

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Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1

Radiotherapy and oncology, 2005-04, Vol.75 (1), p.89-98

2005

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Targeting gene expression to hypoxic tumor cells

Nature medicine, 1997-05, Vol.3 (5), p.515-520

1997

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Novel chimeric gene promoters responsive to hypoxia and ionizing radiation

Gene therapy, 2002-10, Vol.9 (20), p.1403-1411

2002

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The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo

Cancer research (Chicago, Ill.), 1997-02, Vol.57 (4), p.570-572

1997

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Limitations of the reporter green fluorescent protein under simulated tumor conditions

Cancer research (Chicago, Ill.), 2001-06, Vol.61 (12), p.4784-4790

2001

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Effective gene transfer to solid tumors using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector

Cancer gene therapy, 2002-04, Vol.9 (4), p.399-406

2002

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The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers

The Journal of pathology, 2007-07, Vol.212 (3), p.335-344

2007

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Direct visualization of electroporation-assisted in vivo gene delivery to tumors using intravital microscopy - spatial and time dependent distribution

BMC cancer, 2004-11, Vol.4 (1), p.81-81, Article 81

2004

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Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions

Molecular cancer therapeutics, 2001-12, Vol.1 (2), p.151-160

2001

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Use of horseradish peroxidase for gene-directed enzyme prodrug therapy with paracetamol

British journal of cancer, 2004-05, Vol.90 (9), p.1858-1862

2004

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Mechanisms of cytotoxicity induced by horseradish peroxidase/indole-3-acetic acid gene therapy

Journal of cellular biochemistry, 2002, Vol.87 (2), p.221-232

2002

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Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

Cancer gene therapy, 2000-11, Vol.7 (11), p.1414-1420

2000

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The molecular response of mammalian cells to hypoxia and the potential for exploitation in cancer therapy

British journal of cancer. Supplement, 1996-07, Vol.27, p.S126-S132

1996

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Analysis of the horseradish peroxidase indole-3-acetic acid combination in a three-dimensional tumor model

Cancer gene therapy, 2004-07, Vol.11 (7), p.508-513

2004

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5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy

Biochemical pharmacology, 2002-01, Vol.63 (2), p.265-272

2002

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Oxic and anoxic enhancement of radiation-mediated toxicity by horseradish peroxidase/indole-3-acetic acid gene therapy

International journal of radiation biology, 2002-03, Vol.78 (3), p.173-181

2002

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Gene delivery to hypoxic cells in vitro

British journal of cancer, 2000-09, Vol.83 (5), p.662-667

2000

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Can Gene Therapy Overcome the Problem of Hypoxia in Radiotherapy?

JOURNAL OF RADIATION RESEARCH, 2000, Vol.41 (3), p.201-212

2000

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Effective gene transfer to solid tumors using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector

Cancer gene therapy, 2002-04, Vol.9 (4), p.399-406

2002

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Mode of action of metronidazole and a Bacteroides fragilis metA resistance gene in Escherichia coli

Journal of antimicrobial chemotherapy, 1995-04, Vol.35 (4), p.483-496

1995

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Mode of action of metronidazole and a Bacteroides fragilis met A resistance gene in Escherichia coli

Journal of antimicrobial chemotherapy, 1995, Vol.35 (4), p.483-496

1995

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Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives

Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation

Hypoxia-Inducible Factor-1 Modulates Gene Expression in Solid Tumors and Influences Both Angiogenesis and Tumor Growth

From bench to bedside for gene-directed enzyme prodrug therapy of cancer

Enhanced response to radiotherapy in tumours deficient in the function of hypoxia-inducible factor-1

Targeting gene expression to hypoxic tumor cells

Novel chimeric gene promoters responsive to hypoxia and ionizing radiation

The influence of oxygen tension and pH on the expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast tumor cells grown in vitro and in vivo

Limitations of the reporter green fluorescent protein under simulated tumor conditions

Effective gene transfer to solid tumors using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector

The angiogenic factor thymidine phosphorylase up-regulates the cell adhesion molecule P-selectin in human vascular endothelial cells and is associated with P-selectin expression in breast cancers

Direct visualization of electroporation-assisted in vivo gene delivery to tumors using intravital microscopy - spatial and time dependent distribution

Horseradish peroxidase-mediated gene therapy: choice of prodrugs in oxic and anoxic tumor conditions

Use of horseradish peroxidase for gene-directed enzyme prodrug therapy with paracetamol

Mechanisms of cytotoxicity induced by horseradish peroxidase/indole-3-acetic acid gene therapy

Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

The molecular response of mammalian cells to hypoxia and the potential for exploitation in cancer therapy

Analysis of the horseradish peroxidase indole-3-acetic acid combination in a three-dimensional tumor model

5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy

Oxic and anoxic enhancement of radiation-mediated toxicity by horseradish peroxidase/indole-3-acetic acid gene therapy

Gene delivery to hypoxic cells in vitro

Can Gene Therapy Overcome the Problem of Hypoxia in Radiotherapy?

Effective gene transfer to solid tumors using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector

Mode of action of metronidazole and a Bacteroides fragilis metA resistance gene in Escherichia coli

Mode of action of metronidazole and a Bacteroides fragilis met A resistance gene in Escherichia coli

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