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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

Journal of ethnopharmacology, 2010-01, Vol.127 (1), p.7-10

2010

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An Uncertainty-Guided Deep Learning Method Facilitates Rapid Screening of CYP3A4 Inhibitors

Journal of chemical information and modeling, 2023-12, Vol.63 (24), p.7699-7710

2023

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Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

Drug metabolism and disposition, 2017-09, Vol.45 (9), p.1035-1043

2017

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Discovery of a Novel, Potent Spirocyclic Series of γ‑Secretase Inhibitors

Journal of medicinal chemistry, 2015-11, Vol.58 (22), p.8806-8817

2015

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Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema

British journal of pharmacology, 2008-03, Vol.153 (5), p.947-955

2008

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6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

European journal of medicinal chemistry, 2014-10, Vol.85, p.418-437

2014

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Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450

European journal of pharmaceutical sciences, 2015-06, Vol.73, p.49-56

2015

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8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

European journal of medicinal chemistry, 2016-11, Vol.124, p.1041-1056

2016

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Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Neuropharmacology, 2014-12, Vol.87, p.214-221

2014

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Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula

Clinical and experimental pharmacology & physiology, 2015-07, Vol.42 (7), p.795-807

2015

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Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models

Drug metabolism and disposition, 2015-07, Vol.43 (7), p.1147-1153

2015

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Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells

The AAPS journal, 2016-01, Vol.18 (1), p.134-145

2016

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Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase

Drug metabolism and disposition, 2015-07, Vol.43 (7), p.1119-1122

2015

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Chronic Stimulation of the Tone of Endogenous Anandamide Reduces Cue- and Stress-Induced Relapse in Rats

The international journal of neuropsychopharmacology, 2015-01, Vol.18 (1), p.1-5

2015

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In vitro studies of Gynura divaricata (L.) DC extracts as inhibitors of key enzymes relevant for type 2 diabetes and hypertension

Journal of ethnopharmacology, 2011-06, Vol.136 (2), p.305-308

2011

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The role of biotransformation and oxidative stress in 3,5-dichloroaniline (3,5-DCA) induced nephrotoxicity in isolated renal cortical cells from male Fischer 344 rats

Toxicology (Amsterdam), 2016-02, Vol.341, p.47-55

2016

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molecular mechanisms of interactions between bioactive peptides and angiotensin-converting enzyme

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (13), p.3898-3904

2011

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DDPH, a novel antihypertensive agent, is a potential dual inhibitor of hepatic CYP2D and CYP3A

Chemico-biological interactions, 2016-03, Vol.247, p.55-63

2016

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Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells

European journal of pharmacology, 2003-02, Vol.462 (1), p.193-198

2003

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Drug-drug and food-drug pharmacokinetic interactions with new insulinotropic agents repaglinide and nateglinide

Clinical pharmacokinetics, 2007-01, Vol.46 (2), p.93-108

SCHEEN, André J

2007

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Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

European journal of medicinal chemistry, 2015-01, Vol.90, p.124-169

2015

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Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors

Journal of medicinal chemistry, 2017-02, Vol.60 (4), p.1262-1271

2017

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FDA-approved small-molecule kinase inhibitors

Trends in pharmacological sciences (Regular ed.), 2015-07, Vol.36 (7), p.422-439

2015

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Synthesis and in Vitro Evaluation of the Antitubercular and Antibacterial Activity of Novel Oxazolidinones Bearing Octahydrocyclopenta[c]pyrrol-2-yl Moieties

Chemical and Pharmaceutical Bulletin, 2014/12/01, Vol.62(12), pp.1214-1224

2014

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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

An Uncertainty-Guided Deep Learning Method Facilitates Rapid Screening of CYP3A4 Inhibitors

Inhibitory Effects of Selected Antituberculosis Drugs on Common Human Hepatic Cytochrome P450 and UDP-glucuronosyltransferase Enzymes

Discovery of a Novel, Potent Spirocyclic Series of γ‑Secretase Inhibitors

Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin‐mediated angioedema

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula

Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models

Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells

Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase

Chronic Stimulation of the Tone of Endogenous Anandamide Reduces Cue- and Stress-Induced Relapse in Rats

In vitro studies of Gynura divaricata (L.) DC extracts as inhibitors of key enzymes relevant for type 2 diabetes and hypertension

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

The role of biotransformation and oxidative stress in 3,5-dichloroaniline (3,5-DCA) induced nephrotoxicity in isolated renal cortical cells from male Fischer 344 rats

molecular mechanisms of interactions between bioactive peptides and angiotensin-converting enzyme

DDPH, a novel antihypertensive agent, is a potential dual inhibitor of hepatic CYP2D and CYP3A

Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-α- and interleukin-8 release in human bronchial epithelial cells

Drug-drug and food-drug pharmacokinetic interactions with new insulinotropic agents repaglinide and nateglinide

Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors

FDA-approved small-molecule kinase inhibitors

Synthesis and in Vitro Evaluation of the Antitubercular and Antibacterial Activity of Novel Oxazolidinones Bearing Octahydrocyclopenta[c]pyrrol-2-yl Moieties

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