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Ghrelin octanoylation mediated by an orphan lipid transferase

Proceedings of the National Academy of Sciences - PNAS, 2008-04, Vol.105 (17), p.6320-6325

2008

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Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

mAbs, 2015-05, Vol.7 (3), p.483-493

2015

Volltextzugriff (PDF)

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Blood, 2009-05, Vol.113 (21), p.5277-5286

2009

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Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Gut, 2014-12, Vol.63 (12), p.1951-1959

2014

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The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies

mAbs, 2015-11, Vol.7 (6), p.1084-1093

2015

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High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

The Journal of nutritional biochemistry, 2012-12, Vol.23 (12), p.1600-1608

2012

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Influence of physiochemical properties on the subcutaneous absorption and bioavailability of monoclonal antibodies

mAbs, 2020-01, Vol.12 (1), p.1770028

2020

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Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry

Blood, 2007-08, Vol.110 (3), p.1048-1054

2007

Volltextzugriff (PDF)

FcRn affinity-pharmacokinetic relationship of five human IgG4 antibodies engineered for improved in vitro FcRn binding properties in cynomolgus monkeys

Drug metabolism and disposition, 2012-08, Vol.40 (8), p.1545

2012

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Neonatal Fc receptor mediates internalization of Fc in transfected human endothelial cells

Molecular biology of the cell, 2008-12, Vol.19 (12), p.5490-5505

2008

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Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates

Drug metabolism and disposition, 2007-01, Vol.35 (1), p.86

2007

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Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Haematologica (Roma), 2014-09, Vol.99 (9), p.1516

2014

Volltextzugriff (PDF)

Influence of improved FcRn binding on the subcutaneous bioavailability of monoclonal antibodies in cynomolgus monkeys

mAbs, 2012-03, Vol.4 (2), p.267-273

2012

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Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody

mAbs, 2020-01, Vol.12 (1), p.1831880

2020

Volltextzugriff (PDF)

Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency

British journal of haematology, 2009-03, Vol.144 (5), p.789-793

2009

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Targeting the hepcidin–ferroportin pathway in anaemia of chronic kidney disease

British journal of clinical pharmacology, 2019-05, Vol.85 (5), p.935-948

2019

Volltextzugriff (PDF)

Glycosylation of Erythropoietin Affects Receptor Binding Kinetics: Role of Electrostatic Interactions

Biochemistry (Easton), 2002-12, Vol.41 (49), p.14524-14531

2002

Volltextzugriff (PDF)

Monoclonal Antibody Clearance: IMPACT OF MODULATING THE INTERACTION OF IgG WITH THE NEONATAL Fc RECEPTOR

The Journal of biological chemistry, 2007-01, Vol.282 (3), p.1709-1717

2007

Volltextzugriff (PDF)

Modulation of IgG1 immunoeffector function by glycoengineering of the GDP‐fucose biosynthesis pathway

Biotechnology and bioengineering, 2018-03, Vol.115 (3), p.705-718

2018

Volltextzugriff (PDF)

Novel Ghrelin Assays Provide Evidence for Independent Regulation of Ghrelin Acylation and Secretion in Healthy Young Men

The journal of clinical endocrinology and metabolism, 2008-05, Vol.93 (5), p.1980-1987

2008

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Tumor-derived death receptor 6 modulates dendritic cell development

Cancer Immunology, Immunotherapy, 2008-06, Vol.57 (6), p.777-787

2008

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Structural basis of selectivity and neutralizing activity of a TGFα/epiregulin specific antibody

Protein science, 2016-11, Vol.25 (11), p.2028-2036

2016

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Ghrelin octanoylation mediated by an orphan lipid transferase

Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies

High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

Influence of physiochemical properties on the subcutaneous absorption and bioavailability of monoclonal antibodies

Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry

FcRn affinity-pharmacokinetic relationship of five human IgG4 antibodies engineered for improved in vitro FcRn binding properties in cynomolgus monkeys

Neonatal Fc receptor mediates internalization of Fc in transfected human endothelial cells

Humanized IgG1 variants with differential binding properties to the neonatal Fc receptor: relationship to pharmacokinetics in mice and primates

Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Influence of improved FcRn binding on the subcutaneous bioavailability of monoclonal antibodies in cynomolgus monkeys

Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

The Therapeutic Monoclonal Antibody Bamlanivimab Does Not Enhance SARS-CoV-2 Infection by FcR-Mediated Mechanisms

A nondepleting anti-CD19 antibody impairs B cell function and inhibits autoimmune diseases

Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency

Targeting the hepcidin–ferroportin pathway in anaemia of chronic kidney disease

Glycosylation of Erythropoietin Affects Receptor Binding Kinetics: Role of Electrostatic Interactions

Monoclonal Antibody Clearance: IMPACT OF MODULATING THE INTERACTION OF IgG WITH THE NEONATAL Fc RECEPTOR

Modulation of IgG1 immunoeffector function by glycoengineering of the GDP‐fucose biosynthesis pathway

Novel Ghrelin Assays Provide Evidence for Independent Regulation of Ghrelin Acylation and Secretion in Healthy Young Men

Tumor-derived death receptor 6 modulates dendritic cell development

Structural basis of selectivity and neutralizing activity of a TGFα/epiregulin specific antibody

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