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Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (21), p.E4223-E4232

2017

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A structural perspective on the design of decoy immune modulators

Pharmacological research, 2021-08, Vol.170, p.105735-105735, Article 105735

2021

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Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4154-4159

2009

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The CC' loop of IgV domains of the immune checkpoint receptors, plays a key role in receptor:ligand affinity modulation

Scientific reports, 2019-12, Vol.9 (1), p.19191-13, Article 19191

2019

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HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

The Journal of experimental medicine, 2021-12, Vol.218 (12)

2021

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Structural Characterization of LpqH (19 kDa surface antigen), an Immunomodulatory Lipoprotein of Mycobacterium tuberculosis

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Structure and T Cell Inhibition Properties of B7 Family Member, B7-H3

Structure (London), 2013-05, Vol.21 (5), p.707-717

2013

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Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors

Nature communications, 2014-06, Vol.5 (1), p.4124-4124, Article 4124

2014

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Structural Basis of CD160:HVEM Recognition

Structure (London), 2019-08, Vol.27 (8), p.1286-1295.e4

2019

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Structure and Cancer Immunotherapy of the B7 Family Member B7x

Cell reports (Cambridge), 2014-11, Vol.9 (3), p.1089-1098

2014

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Cumulative phylogenetic, sequence and structural analysis of Insulin superfamily proteins provide unique structure-function insights

Molecular informatics, 2024-07, Vol.43 (9), p.e202300160

2024

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A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals

PLoS pathogens, 2016-09, Vol.12 (9), p.e1005849

2016

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Crystal structures of APRT from Francisella tularensis – an N–H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases

The FEBS journal, 2018-06, Vol.285 (12), p.2306-2318

2018

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Cryptic association of B7‐2 molecules and its implication for clustering

Protein science, 2021-09, Vol.30 (9), p.1958-1973

2021

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Structural, mutational and biophysical studies reveal a canonical mode of molecular recognition between immune receptor TIGIT and nectin-2

Molecular immunology, 2017-01, Vol.81 (C), p.151-159

2017

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High-resolution crystal structure of LpqH, an immunomodulatory surface lipoprotein of Mycobacterium tuberculosis reveals a distinct fold and a conserved cleft on its surface

International journal of biological macromolecules, 2022-06, Vol.210, p.494-503

2022

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Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesion

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (37), p.14836-14840

2012

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Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy

EBioMedicine, 2017-03, Vol.17 (C), p.30-44

2017

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Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (2), p.635-640

2008

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Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module

Biochemistry (Easton), 2018-02, Vol.57 (8), p.1293-1305

2018

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Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (49), p.19452-19457

2007

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Phenothiazines inhibit S100A4 function by inducing protein oligomerization

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (19), p.8605-8610

2010

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Functional Classification of Immune Regulatory Proteins

Structure (London), 2013-05, Vol.21 (5), p.766-776

2013

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Sequence, structure, function, immunity: structural genomics of costimulation

Immunological reviews, 2009-05, Vol.229 (1), p.356-386

2009

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Can the propensity of protein crystallization be increased by using systematic screening with metals?

Protein science, 2017-09, Vol.26 (9), p.1704-1713

2017

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Structural basis for cancer immunotherapy by the first-in-class checkpoint inhibitor ipilimumab

A structural perspective on the design of decoy immune modulators

Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

The CC' loop of IgV domains of the immune checkpoint receptors, plays a key role in receptor:ligand affinity modulation

HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

Structural Characterization of LpqH (19 kDa surface antigen), an Immunomodulatory Lipoprotein of Mycobacterium tuberculosis

Structure and T Cell Inhibition Properties of B7 Family Member, B7-H3

Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors

Structural Basis of CD160:HVEM Recognition

Structure and Cancer Immunotherapy of the B7 Family Member B7x

Cumulative phylogenetic, sequence and structural analysis of Insulin superfamily proteins provide unique structure-function insights

A Small Protein Associated with Fungal Energy Metabolism Affects the Virulence of Cryptococcus neoformans in Mammals

Crystal structures of APRT from Francisella tularensis – an N–H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases

Cryptic association of B7‐2 molecules and its implication for clustering

Structural, mutational and biophysical studies reveal a canonical mode of molecular recognition between immune receptor TIGIT and nectin-2

High-resolution crystal structure of LpqH, an immunomodulatory surface lipoprotein of Mycobacterium tuberculosis reveals a distinct fold and a conserved cleft on its surface

Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesion

Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy

Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily

Structures of the L27 Domain of Disc Large Homologue 1 Protein Illustrate a Self-Assembly Module

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function

Phenothiazines inhibit S100A4 function by inducing protein oligomerization

Functional Classification of Immune Regulatory Proteins

Sequence, structure, function, immunity: structural genomics of costimulation

Can the propensity of protein crystallization be increased by using systematic screening with metals?

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