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Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1

Scientific reports, 2023-05, Vol.13 (1), p.7906-7906, Article 7906

2023

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Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (37), p.14942-14947

2013

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Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein

Scientific reports, 2016-02, Vol.6 (1), p.21994-21994, Article 21994

2016

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Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery

International journal of molecular sciences, 2021-01, Vol.22 (2), p.828

2021

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Analyzing the Folding and Binding Steps of an Intrinsically Disordered Protein by Protein Engineering

Biochemistry (Easton), 2017-07, Vol.56 (29), p.3780-3786

2017

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Folding and Binding Kinetics of the Tandem of SH2 Domains from SHP2

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6566

2024

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SH2 Domains: Folding, Binding and Therapeutical Approaches

International journal of molecular sciences, 2022-12, Vol.23 (24), p.15944

2022

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PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2

Scientific reports, 2024-06, Vol.14 (1), p.13059-11

2024

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Understanding the Binding Induced Folding of Intrinsically Disordered Proteins by Protein Engineering: Caveats and Pitfalls

International journal of molecular sciences, 2020-05, Vol.21 (10), p.3484

2020

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Experimental Characterization of the Interaction between the N-Terminal SH3 Domain of Crkl and C3G

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13174

2021

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Unveiling the Molecular Basis of the Noonan Syndrome-Causing Mutation T42A of SHP2

International journal of molecular sciences, 2020-01, Vol.21 (2), p.461

2020

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Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (39), p.14141-14146

2014

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Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering

International journal of molecular sciences, 2023-12, Vol.24 (24), p.17364

2023

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Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners

International journal of molecular sciences, 2023-06, Vol.24 (12), p.10138

2023

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The Effect of Proline cis - trans Isomerization on the Folding of the C-Terminal SH2 Domain from p85

International journal of molecular sciences, 2019-12, Vol.21 (1), p.125

2019

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GRB2: A dynamic adaptor protein orchestrating cellular signaling in health and disease

Biochemistry and biophysics reports, 2024-09, Vol.39, p.101803, Article 101803

2024

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Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer

Biology direct, 2021-10, Vol.16 (1), p.15-21, Article 15

2021

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Understanding the Mechanism of Recognition of Gab2 by the N-SH2 Domain of SHP2

Life (Basel, Switzerland), 2020-06, Vol.10 (6), p.85

2020

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Editorial: Intrinsically Disordered Proteins and Regions: The Challenge to the Structure-Function Relationship

Frontiers in molecular biosciences, 2022-07, Vol.9, p.962643-962643

2022

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On the Effects of Disordered Tails, Supertertiary Structure and Quinary Interactions on the Folding and Function of Protein Domains

Biomolecules (Basel, Switzerland), 2022-01, Vol.12 (2), p.209

2022

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Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins

Computational and structural biotechnology journal, 2021-01, Vol.19, p.1838-1847

2021

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Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State

International journal of molecular sciences, 2019-01, Vol.20 (2), p.396

2019

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Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains

Scientific reports, 2017-08, Vol.7 (1), p.7875-9, Article 7875

2017

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Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein

Computational and structural biotechnology journal, 2023-01, Vol.21, p.3259-3271

2023

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Different electrostatic forces drive the binding kinetics of SARS-CoV, SARS-CoV-2 and MERS-CoV Envelope proteins with the PDZ2 domain of ZO1

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system

Molecular Recognition by Templated Folding of an Intrinsically Disordered Protein

Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery

Analyzing the Folding and Binding Steps of an Intrinsically Disordered Protein by Protein Engineering

Folding and Binding Kinetics of the Tandem of SH2 Domains from SHP2

SH2 Domains: Folding, Binding and Therapeutical Approaches

PDZ2-conjugated-PLGA nanoparticles are tiny heroes in the battle against SARS-CoV-2

Understanding the Binding Induced Folding of Intrinsically Disordered Proteins by Protein Engineering: Caveats and Pitfalls

Experimental Characterization of the Interaction between the N-Terminal SH3 Domain of Crkl and C3G

Unveiling the Molecular Basis of the Noonan Syndrome-Causing Mutation T42A of SHP2

Understanding the frustration arising from the competition between function, misfolding, and aggregation in a globular protein

Addressing the Binding Mechanism of the Meprin and TRAF-C Homology Domain of the Speckle-Type POZ Protein Using Protein Engineering

Biophysical Characterization of the Binding Mechanism between the MATH Domain of SPOP and Its Physiological Partners

The Effect of Proline cis - trans Isomerization on the Folding of the C-Terminal SH2 Domain from p85

GRB2: A dynamic adaptor protein orchestrating cellular signaling in health and disease

Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer

Understanding the Mechanism of Recognition of Gab2 by the N-SH2 Domain of SHP2

Editorial: Intrinsically Disordered Proteins and Regions: The Challenge to the Structure-Function Relationship

On the Effects of Disordered Tails, Supertertiary Structure and Quinary Interactions on the Folding and Function of Protein Domains

Structural determinants driving the binding process between PDZ domain of wild type human PALS1 protein and SLiM sequences of SARS-CoV E proteins

Anticancer Activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a New Dishevelled 1 Inhibitor

Investigating the Molecular Basis of the Aggregation Propensity of the Pathological D76N Mutant of Beta-2 Microglobulin: Role of the Denatured State

Regulation of the Human Phosphatase PTPN4 by the inter-domain linker connecting the PDZ and the phosphatase domains

Monomeric and dimeric states of human ZO1-PDZ2 are functional partners of the SARS-CoV-2 E protein

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