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Towards Cellular Activation of an Artificial Metalloenzyme: Development of an Artificial Zymogen

Chimia, 2017-04, Vol.71 (4), p.199

Lebrun, Vincent

2017

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Catalytic Zinc Complexes for Phosphate Diester Hydrolysis

Angewandte Chemie (International ed.), 2014-07, Vol.53 (31), p.8246-8250

International ed. in English, 2014

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Anion‑π Enzymes

ACS central science, 2016-06, Vol.2 (6), p.388-393

2016

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Upregulation of an Artificial Zymogen by Proteolysis

Angewandte Chemie (International ed.), 2016-09, Vol.55 (38), p.11587-11590

International ed. in English, 2016

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A Closer Look at Type I Left-Handed β-Helices Provides a Better Understanding in Their Sequence-Structure Relationship: Toward Their Rational Design

Proteins, structure, function, and bioinformatics, 2024-07

2024

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Special issue FrenchBIC 2020: Celebrating BioInorganic Chemistry in France and Germany

Journal of inorganic biochemistry, 2022-02, Vol.227, p.111694-111694, Article 111694

2022

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Artificial Metalloenzymes: Reaction Scope and Optimization Strategies

Chemical reviews, 2018-01, Vol.118 (1), p.142-231

2018

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Interfacing Functional Systems

Chimia, 2016-06, Vol.70 (6), p.418

2016

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How trimerization of CTR1 N-terminal model peptides tunes Cu-binding and redox-chemistry

Chemical communications (Cambridge, England), 2020-10, Vol.56 (81), p.12194-12197

2020

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Revisiting the pro-oxidant activity of copper: interplay of ascorbate, cysteine, and glutathione

Metallomics, 2023-07, Vol.15 (7)

2023

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Burning Amyloid-β with a Near-Infrared Photosensitizer

Chem, 2018-04, Vol.4 (4), p.663-665

2018

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Reversible turn-on fluorescent Cu() sensors: rather dream than reality?

Dalton transactions : an international journal of inorganic chemistry, 2019, Vol.48 (38), p.14233-14237

2019

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Model peptide for anti-sigma factor domain HHCC zinc fingers: high reactivity toward 1 O 2 leads to domain unfolding

Chemical science (Cambridge), 2019-03, Vol.10 (12), p.3608-3615

2019

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Model peptide for anti-sigma factor domain HHCC zinc fingers: high reactivity toward 1O2 leads to domain unfolding

Chemical science (Cambridge), 2019-03, Vol.10 (12), p.3608-3615

2019

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Model peptide for anti-sigma factor domain HHCC zinc fingers: high reactivity toward 1O2 leads to domain unfolding† †Electronic supplementary information (ESI) available: Experimental details for peptide synthesis and characterization, absorption and circular dichroism analyses of Zn2+ binding, H2O2 oxidation, 1O2 oxidation and solution structure determination by NMR. See DOI: 10.1039/c9sc00341j

Chemical science (Cambridge), 2019-02, Vol.10 (12), p.3608-3615

2019

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Copper-binding motifs Xxx-His or Xxx-Zzz-His (ATCUN) linked to an antimicrobial peptide: Cu-binding, antimicrobial activity and ROS production

Journal of inorganic biochemistry, 2020-12, Vol.213, p.111255-111255, Article 111255

2020

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Near diffusion-controlled reaction of a Zn(Cys)4 zinc finger with hypochlorous acidElectronic supplementary information (ESI) available: Experimental details concerning absorption, fluorescence and HPLC monitoring of the HOCl oxidation of Zn·LHSP, identification of oxidation products, stopped-flow experiments, re-assessment of rate constants for methionine oxidation and simulation of competitive HOCl titrations of methionine and Zn·LHSP. See DOI: 10.1039/c6sc00974c

2016-07

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Quest for a stable Cu-ligand complex with a high catalytic activity to produce reactive oxygen species

Metallomics, 2024-05, Vol.16 (5)

2024

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Near diffusion-controlled reaction of a Zn(Cys)4 zinc finger with hypochlorous acid† †Electronic supplementary information (ESI) available: Experimental details concerning absorption, fluorescence and HPLC monitoring of the HOCl oxidation of Zn·LHSP, identification of oxidation products, stopped-flow experiments, re-assessment of rate constants for methionine oxidation and simulation of competitive HOCl titrations of methionine and Zn·LHSP. See DOI: 10.1039/c6sc00974c

Chemical science (Cambridge), 2016-05, Vol.7 (8), p.5508-5516

2016

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Reactivity of a Zn(Cys) sub(2)(His) sub(2) Zinc Finger with Singlet Oxygen: Oxidation Directed toward Cysteines but not Histidines

Chemistry : a European journal, 2015-09, Vol.21 (40), p.14002-14010

2015

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Reactivity of a Zn(Cys)2(His)2 Zinc Finger with Singlet Oxygen: Oxidation Directed toward Cysteines but not Histidines

Chemistry : a European journal, 2015-09, Vol.21 (40), p.14002-14010

2015

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Near diffusion-controlled reaction of a Zn(Cys) 4 zinc finger with hypochlorous acid

Chemical science (Cambridge), 2016, Vol.7 (8), p.5508-5516

2016

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Efficient Oxidation and Destabilization of Zn(Cys) sub(4) Zinc Fingers by Singlet Oxygen

Angewandte Chemie International Edition, 2014-08, Vol.53 (35), p.9365-9368

2014

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Efficient Oxidation and Destabilization of Zn(Cys)4 Zinc Fingers by Singlet Oxygen

Angewandte Chemie (International ed.), 2014-08, Vol.53 (35), p.9365-9368

International ed. in English, 2014

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On the Design of Zinc-Finger Models with Cyclic Peptides Bearing a Linear Tail

Chemistry : a European journal, 2013-03, Vol.19 (12), p.3921-3931

2013

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Towards Cellular Activation of an Artificial Metalloenzyme: Development of an Artificial Zymogen

Catalytic Zinc Complexes for Phosphate Diester Hydrolysis

Anion‑π Enzymes

Upregulation of an Artificial Zymogen by Proteolysis

A Closer Look at Type I Left-Handed β-Helices Provides a Better Understanding in Their Sequence-Structure Relationship: Toward Their Rational Design

Special issue FrenchBIC 2020: Celebrating BioInorganic Chemistry in France and Germany

Artificial Metalloenzymes: Reaction Scope and Optimization Strategies

Interfacing Functional Systems

How trimerization of CTR1 N-terminal model peptides tunes Cu-binding and redox-chemistry

Revisiting the pro-oxidant activity of copper: interplay of ascorbate, cysteine, and glutathione

Burning Amyloid-β with a Near-Infrared Photosensitizer

Reversible turn-on fluorescent Cu() sensors: rather dream than reality?

Model peptide for anti-sigma factor domain HHCC zinc fingers: high reactivity toward 1 O 2 leads to domain unfolding

Model peptide for anti-sigma factor domain HHCC zinc fingers: high reactivity toward 1O2 leads to domain unfolding

Copper-binding motifs Xxx-His or Xxx-Zzz-His (ATCUN) linked to an antimicrobial peptide: Cu-binding, antimicrobial activity and ROS production

Quest for a stable Cu-ligand complex with a high catalytic activity to produce reactive oxygen species

Reactivity of a Zn(Cys) sub(2)(His) sub(2) Zinc Finger with Singlet Oxygen: Oxidation Directed toward Cysteines but not Histidines

Reactivity of a Zn(Cys)2(His)2 Zinc Finger with Singlet Oxygen: Oxidation Directed toward Cysteines but not Histidines

Near diffusion-controlled reaction of a Zn(Cys) 4 zinc finger with hypochlorous acid

Efficient Oxidation and Destabilization of Zn(Cys) sub(4) Zinc Fingers by Singlet Oxygen

Efficient Oxidation and Destabilization of Zn(Cys)4 Zinc Fingers by Singlet Oxygen

On the Design of Zinc-Finger Models with Cyclic Peptides Bearing a Linear Tail

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