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Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators

The Journal of biological chemistry, 2020-08, Vol.295 (32), p.11021-11041

2020

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An optimized bioluminescent substrate for non-invasive imaging in the brain

Nature chemical biology, 2023-06, Vol.19 (6), p.731

2023

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Inhibition of Mitochondrial Antioxidant Defense and CDK4/6 in Mesothelioma

Molecules (Basel, Switzerland), 2023-05, Vol.28 (11), p.4380

2023

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Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6

Nature communications, 2020-10, Vol.11 (1), p.5244-5244, Article 5244

2020

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Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer

Cell reports (Cambridge), 2015-10, Vol.13 (3), p.479-488

2015

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Stabilized Helical Peptides: A Strategy to Target Protein–Protein Interactions

ACS medicinal chemistry letters, 2014-08, Vol.5 (8), p.838-839

Klein, Mark A

2014

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Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health

Particle and fibre toxicology, 2024-10, Vol.21 (1), p.43-12, Article 43

2024

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Luciferase Calibrants Enable Absolute Quantitation of Bioluminescence Power

ACS measurement science au, 2023-12, Vol.3 (6), p.496-503

2023

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The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

PLoS genetics, 2016-12, Vol.12 (12), p.e1006466-e1006466

2016

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Cyclin-Dependent Kinase and Antioxidant Gene Expression in Cancers with Poor Therapeutic Response

Pharmaceuticals (Basel, Switzerland), 2020-02, Vol.13 (2), p.26

2020

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CX-4945 and siRNA-Mediated Knockdown of CK2 Improves Cisplatin Response in HPV(+) and HPV(−) HNSCC Cell Lines

Biomedicines, 2021-05, Vol.9 (5), p.571

2021

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Targeting RET alterations in non-small cell lung cancer

Current problems in cancer, 2024-04, Vol.49, p.101074-101074, Article 101074

2024

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Mechanism of activation for the sirtuin 6 protein deacylase

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1385-1399

2020

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Protein kinase CK2 – diverse roles in cancer cell biology and therapeutic promise

Molecular and cellular biochemistry, 2023-04, Vol.478 (4), p.899-926

2023

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Metastin (KiSS-1) Mimetics Identified from Peptide Structure−Activity Relationship-Derived Pharmacophores and Directed Small Molecule Database Screening

Journal of medicinal chemistry, 2007-02, Vol.50 (3), p.462-471

2007

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Sirt6 regulates lifespan in Drosophila melanogaster

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (5)

2022

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Cyclin-dependent kinase inhibition: an opportunity to target protein-protein interactions

Advances in protein chemistry and structural biology, 2020, Vol.121, p.115

Klein, Mark A

2020

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Correction: Protein kinase CK2 – diverse roles in cancer cell biology and therapeutic promise

Molecular and cellular biochemistry, 2023-07, Vol.478 (7), p.1659-1659

2023

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Potent Activation of NAD+‑Dependent Deacetylase Sirt7 by Nucleosome Binding

ACS chemical biology, 2022-08, Vol.17 (8), p.2248-2261

2022

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Trajectory of Healthcare Contact Days for Veterans With Advanced Gastrointestinal Malignancy

The oncologist (Dayton, Ohio), 2024-02, Vol.29 (2), p.e290-e293

2024

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DARPP-32 promotes ERBB3-mediated resistance to molecular targeted therapy in EGFR-mutated lung adenocarcinoma

Oncogene, 2022-01, Vol.41 (1), p.83-98

2022

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Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

The Journal of biological chemistry, 2023-12, Vol.299 (12), p.105407, Article 105407

2023

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Mechanism of activation for the sirtuin 6 protein deacylase

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1385-1399

2020

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An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality

Genes & development, 2018-03, Vol.32 (5-6), p.373-388

2018

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Gross Hematuria and Lower Urinary Tract Symptoms Associated With Military Burn Pits Exposures in US Veterans Deployed to Iraq and Afghanistan

Journal of occupational and environmental medicine, 2023-09, Vol.65 (9), p.740-744

2023

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Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators

An optimized bioluminescent substrate for non-invasive imaging in the brain

Inhibition of Mitochondrial Antioxidant Defense and CDK4/6 in Mesothelioma

Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6

Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer

Stabilized Helical Peptides: A Strategy to Target Protein–Protein Interactions

Current understanding of the impact of United States military airborne hazards and burn pit exposures on respiratory health

Luciferase Calibrants Enable Absolute Quantitation of Bioluminescence Power

The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

Cyclin-Dependent Kinase and Antioxidant Gene Expression in Cancers with Poor Therapeutic Response

CX-4945 and siRNA-Mediated Knockdown of CK2 Improves Cisplatin Response in HPV(+) and HPV(−) HNSCC Cell Lines

Targeting RET alterations in non-small cell lung cancer

Mechanism of activation for the sirtuin 6 protein deacylase

Protein kinase CK2 – diverse roles in cancer cell biology and therapeutic promise

Metastin (KiSS-1) Mimetics Identified from Peptide Structure−Activity Relationship-Derived Pharmacophores and Directed Small Molecule Database Screening

Sirt6 regulates lifespan in Drosophila melanogaster

Cyclin-dependent kinase inhibition: an opportunity to target protein-protein interactions

Correction: Protein kinase CK2 – diverse roles in cancer cell biology and therapeutic promise

Potent Activation of NAD+‑Dependent Deacetylase Sirt7 by Nucleosome Binding

Trajectory of Healthcare Contact Days for Veterans With Advanced Gastrointestinal Malignancy

DARPP-32 promotes ERBB3-mediated resistance to molecular targeted therapy in EGFR-mutated lung adenocarcinoma

Cyclin D1 extensively reprograms metabolism to support biosynthetic pathways in hepatocytes

Mechanism of activation for the sirtuin 6 protein deacylase

An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality

Gross Hematuria and Lower Urinary Tract Symptoms Associated With Military Burn Pits Exposures in US Veterans Deployed to Iraq and Afghanistan

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