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Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice

Hepatology (Baltimore, Md.), 2019-03, Vol.69 (3), p.1105-1121

2019

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Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis

Hepatology (Baltimore, Md.), 2019-02, Vol.69 (2), p.545-563

2019

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Alcohol‐induced miR‐155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

Journal of leukocyte biology, 2017-08, Vol.102 (2), p.487-498

2017

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Metabolic danger signals, uric acid and ATP, mediate inflammatory cross‐talk between hepatocytes and immune cells in alcoholic liver disease

Journal of leukocyte biology, 2015-08, Vol.98 (2), p.249-256

2015

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FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice

Hepatology communications, 2018-11, Vol.2 (11), p.1379-1391

2018

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STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (41), p.16544-16549

2013

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Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use

Journal of hepatology, 2018-11, Vol.69 (5), p.1145-1154

2018

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Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

Journal of neuroinflammation, 2018-10, Vol.15 (1), p.298-298, Article 298

2018

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Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

The Journal of biological chemistry, 2016-12, Vol.291 (52), p.26794-26805

2016

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MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease

Gastroenterology (New York, N.Y. 1943), 2018-01, Vol.154 (1), p.238-252.e7

2018

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Interleukin‐1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice

Liver international, 2017-07, Vol.37 (7), p.968-973

2017

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Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Nature (London), 2019-01, Vol.565 (7737), p.43-48

2019

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Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease

Hepatology (Baltimore, Md.), 2016-10, Vol.64 (4), p.1057-1071

2016

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Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

PloS one, 2017-03, Vol.12 (3), p.e0174544

2017

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MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis

PloS one, 2015-06, Vol.10 (6), p.e0129251-e0129251

2015

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Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice

Journal of hepatology, 2015-11, Vol.63 (5), p.1147-1155

2015

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Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

Journal of neuroinflammation, 2020-10, Vol.17 (1), p.296-296, Article 296

2020

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Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice

Alcoholism, clinical and experimental research, 2016-07, Vol.40 (7), p.1524-1530

2016

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Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

Nature biotechnology, 2012-02, Vol.30 (2), p.179-183

2012

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Modulation of cellular stress response via the erythropoietin/CD131 heteroreceptor complex in mouse mesenchymal-derived cells

Journal of molecular medicine (Berlin, Germany), 2015-02, Vol.93 (2), p.199-210

2015

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Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

PloS one, 2017-05, Vol.12 (5), p.e0179070-e0179070

2017

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IF1-3 Liver-Gut-Brain Interactions in Chronic Liver Disease

Journal of Japanese Society of Gastroenterology, 2018-03, Vol.115 (suppl-1), p.192-192

2018

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Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis

Clinics and research in hepatology and gastroenterology, 2015-09, Vol.39, p.S18-S23

2015

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IL-1α in acetaminophen toxicity: a sterile danger signal

Cellular & molecular immunology, 2018-03, Vol.15 (3), p.284-285

2018

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Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

Nature (London), 2021-07, Vol.595 (7866), p.309-314

2021

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Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice

Macrophage‐Specific Hypoxia‐Inducible Factor‐1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis

Alcohol‐induced miR‐155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease

Metabolic danger signals, uric acid and ATP, mediate inflammatory cross‐talk between hepatocytes and immune cells in alcoholic liver disease

FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice

STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease

Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use

Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression

Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients From Ethanol-Induced Liver Disease

Interleukin‐1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease

Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis

Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

Modulation of cellular stress response via the erythropoietin/CD131 heteroreceptor complex in mouse mesenchymal-derived cells

Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice

IF1-3 Liver-Gut-Brain Interactions in Chronic Liver Disease

Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis

IL-1α in acetaminophen toxicity: a sterile danger signal

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

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