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Assessment of mechanisms driving non-linear dose–response relationships in genotoxicity testing

Mutation research. Reviews in mutation research, 2015-01, Vol.763, p.181-201

2015

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Role of Endogenous Oxidative DNA Damage in Carcinogenesis: What Can We Learn from Repair-Deficient Mice?

Biological chemistry, 2002-01, Vol.383 (3-4)

Epe, B.

2002

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Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice

Oncogene, 2007-06, Vol.26 (27), p.4044-4048

2007

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PO-002 Angiotensin II-induced hypertension increases the mutation frequency in the rat kidney

ESMO open, 2018-07, Vol.3 (Suppl 2), p.A21-A21

2018

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Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide

British journal of pharmacology, 2006-12, Vol.149 (8), p.988-997

2006

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Measurement of DNA oxidation in human cells by chromatographic and enzymic methods

Free radical biology & medicine, 2003-04, Vol.34 (8), p.1089-1099

Collins, Andrew

2003

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DNA damage profiles induced by oxidizing agents

Reviews of physiology, biochemistry and pharmacology, 1996-01, Vol.127, p.223

Epe, B

1996

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DNA damage by bromate: Mechanism and consequences

Toxicology (Amsterdam), 2006-04, Vol.221 (2), p.166-171

2006

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Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence

Nucleic acids research, 2013-10, Vol.41 (18), p.8559-8571

2013

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Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage

Free radical research, 2000, Vol.32 (4), p.333-341

Collins, Andrew

2000

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Role of endogenous oxidative DNA damage in carcinogenesis: what can we learn from repair-deficient mice?

Biological chemistry, 2002-03, Vol.383 (3-4), p.467

Epe, Bernd

2002

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A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance

Cell death and differentiation, 2007-06, Vol.14 (6), p.1149-1161

2007

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Accumulation of Premutagenic DNA Lesions in Mice Defective in Removal of Oxidative Base Damage

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (23), p.13300-13305

1999

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Wavelength dependence of oxidative DNA damage induced by UV and visible light

Carcinogenesis (New York), 1997-04, Vol.18 (4), p.811-816

1997

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Photolysis of N-Hydroxypyridinethiones: A New Source of Hydroxyl Radicals for the Direct Damage of Cell-Free and Cellular DNA

Nucleic acids research, 1996-05, Vol.24 (9), p.1625-1631

1996

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8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein

DNA repair, 2009-03, Vol.8 (3), p.309-317

2009

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Alterations of DNA Repair in Melanoma Cell Lines Resistant to Cisplatin, Fotemustine, or Etoposide

Journal of investigative dermatology, 2000-01, Vol.114 (1), p.34-39

2000

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Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study

The FASEB journal, 2005-01, Vol.19 (1), p.82-84

2005

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Squaraine Dyes for Photodynamic Therapy: Mechanism of Cytotoxicity and DNA Damage Induced by Halogenated Squaraine Dyes Plus Light (>600 nm)

Photochemistry and photobiology, 2004-01, Vol.79 (1), p.99-104

2004

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Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected

Carcinogenesis (New York), 2003-01, Vol.24 (1), p.63-73

2003

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Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts

Carcinogenesis (New York), 2005-03, Vol.26 (3), p.547-555

2005

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A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage

Oncogene, 2002-11, Vol.21 (54), p.8232-8239

2002

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Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells

DNA repair, 2008-06, Vol.7 (6), p.912-921

2008

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Problems in the measurement of 8-oxoguanine in human DNA. Report of a workshop, DNA oxidation, held in Aberdeen, UK, 19-21 January, 1997

Carcinogenesis (New York), 1997-09, Vol.18 (9), p.1833-1836

1997

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Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus

Carcinogenesis (New York), 2002-12, Vol.23 (12), p.2129-2133

Collins, A

2002

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Assessment of mechanisms driving non-linear dose–response relationships in genotoxicity testing

Role of Endogenous Oxidative DNA Damage in Carcinogenesis: What Can We Learn from Repair-Deficient Mice?

Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice

PO-002 Angiotensin II-induced hypertension increases the mutation frequency in the rat kidney

Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide

Measurement of DNA oxidation in human cells by chromatographic and enzymic methods

DNA damage profiles induced by oxidizing agents

DNA damage by bromate: Mechanism and consequences

Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence

Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage

Role of endogenous oxidative DNA damage in carcinogenesis: what can we learn from repair-deficient mice?

A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance

Accumulation of Premutagenic DNA Lesions in Mice Defective in Removal of Oxidative Base Damage

Wavelength dependence of oxidative DNA damage induced by UV and visible light

Photolysis of N-Hydroxypyridinethiones: A New Source of Hydroxyl Radicals for the Direct Damage of Cell-Free and Cellular DNA

8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein

Alterations of DNA Repair in Melanoma Cell Lines Resistant to Cisplatin, Fotemustine, or Etoposide

Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study

Squaraine Dyes for Photodynamic Therapy: Mechanism of Cytotoxicity and DNA Damage Induced by Halogenated Squaraine Dyes Plus Light (>600 nm)

Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected

Incorporation of dUMP into DNA is a major source of spontaneous DNA damage, while excision of uracil is not required for cytotoxicity of fluoropyrimidines in mouse embryonic fibroblasts

A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage

Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells

Problems in the measurement of 8-oxoguanine in human DNA. Report of a workshop, DNA oxidation, held in Aberdeen, UK, 19-21 January, 1997

Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus

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