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Genetic and epigenetic regulation of human aging and longevity

Biochimica et biophysica acta. Molecular basis of disease, 2019-07, Vol.1865 (7), p.1718-1744

2019

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FOXO3: A Major Gene for Human Longevity - A Mini-Review

Gerontology (Basel), 2015-01, Vol.61 (6), p.515-525

2015

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FOXO3A genotype is strongly associated with human longevity

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (37), p.13987-13992

2008

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Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations

American journal of human genetics, 2013-06, Vol.92 (6), p.904-916

2013

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Shorter men live longer: association of height with longevity and FOXO3 genotype in American men of Japanese ancestry

PloS one, 2014-05, Vol.9 (5), p.e94385-e94385

2014

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The FoxO3 gene and cause‐specific mortality

Aging cell, 2016-08, Vol.15 (4), p.617-624

2016

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FOXO3 and Exceptional Longevity: Insights From Hydra to Humans

Current topics in developmental biology, 2018, Vol.127, p.193-212

2018

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Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele

The journals of gerontology. Series A, Biological sciences and medical sciences, 2018-10, Vol.73 (11), p.1448-1452

2018

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FOXO transcription factors as therapeutic targets in human diseases

Trends in pharmacological sciences (Regular ed.), 2022-12, Vol.43 (12), p.1070-1084

2022

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Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype

GeroScience, 2023-08, Vol.45 (4), p.2303-2324

2023

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Genes That Extend Lifespan May Do So by Mitigating the Increased Risk of Death Posed by Having Hypertension

American journal of hypertension, 2023-11, Vol.36 (12), p.631-640

2023

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Novel Functional, Health, and Genetic Determinants of Cognitive Terminal Decline: Kuakini Honolulu Heart Program/Honolulu-Asia Aging Study

The journals of gerontology. Series A, Biological sciences and medical sciences, 2022-08, Vol.77 (8), p.1525-1533

2022

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FOXO3 longevity interactome on chromosome 6

Aging cell, 2017-10, Vol.16 (5), p.1016-1025

2017

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Association with Longevity of Phosphatidylinositol 3-Kinase Regulatory Subunit 1 Gene Variants Stems from Protection against Mortality Risk in Men with Cardiovascular Disease

Gerontology (Basel), 2022-02, Vol.68 (2), p.162-170

2022

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Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity

Ageing research reviews, 2022-06, Vol.78, p.101621, Article 101621

2022

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Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity

The journals of gerontology. Series A, Biological sciences and medical sciences, 2018-10, Vol.73 (11), p.1459-1464

2018

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Case-Control Study of Ovarian Cancer and Polymorphisms in Genes Involved in Catecholestrogen Formation and Metabolism

Cancer epidemiology, biomarkers & prevention, 2001-03, Vol.10 (3), p.209-216

2001

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In silico analysis of human renin gene–gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases

Biogerontology (Dordrecht), 2019-12, Vol.20 (6), p.857-869

2019

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FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk

Journal of hypertension, 2024-03, Vol.42 (3), p.484-489

2024

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Circulating microRNA profile of long‐lived Okinawans identifies novel potential targets for optimizing lifespan and health span

Aging cell, 2024-08, Vol.23 (8), p.e14191-n/a

2024

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Vascular endothelial growth factor receptor 1 gene ( FLT1 ) longevity variant increases lifespan by reducing mortality risk posed by hypertension

Aging (Albany, NY.), 2023-05, Vol.15 (10), p.3967-3983

2023

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Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage

Journal of hypertension, 2022-11, Vol.40 (11), p.2230-2235

2022

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Incidence of Alzheimer's Disease in Men with Late-Life Hypertension Is Ameliorated by FOXO3 Longevity Genotype

Journal of Alzheimer's disease, 2023-08, Vol.95 (1), p.79-91

2023

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FOXO3, a Resilience Gene: Impact on Lifespan, Healthspan, and Deathspan

The journals of gerontology. Series A, Biological sciences and medical sciences, 2022-08, Vol.77 (8), p.1479-1484

2022

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Association of Methylenetetrahydrofolate Reductase Polymorphism C677T and Dietary Folate with the Risk of Cervical Dysplasia

Cancer epidemiology, biomarkers & prevention, 2001-12, Vol.10 (12), p.1275-1280

2001

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Genetic and epigenetic regulation of human aging and longevity

FOXO3: A Major Gene for Human Longevity - A Mini-Review

FOXO3A genotype is strongly associated with human longevity

Genome-wide Characterization of Shared and Distinct Genetic Components that Influence Blood Lipid Levels in Ethnically Diverse Human Populations

Shorter men live longer: association of height with longevity and FOXO3 genotype in American men of Japanese ancestry

The FoxO3 gene and cause‐specific mortality

FOXO3 and Exceptional Longevity: Insights From Hydra to Humans

Minimal Shortening of Leukocyte Telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele

FOXO transcription factors as therapeutic targets in human diseases

Proteomic basis of mortality resilience mediated by FOXO3 longevity genotype

Genes That Extend Lifespan May Do So by Mitigating the Increased Risk of Death Posed by Having Hypertension

Novel Functional, Health, and Genetic Determinants of Cognitive Terminal Decline: Kuakini Honolulu Heart Program/Honolulu-Asia Aging Study

FOXO3 longevity interactome on chromosome 6

Association with Longevity of Phosphatidylinositol 3-Kinase Regulatory Subunit 1 Gene Variants Stems from Protection against Mortality Risk in Men with Cardiovascular Disease

Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity

Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity

Case-Control Study of Ovarian Cancer and Polymorphisms in Genes Involved in Catecholestrogen Formation and Metabolism

In silico analysis of human renin gene–gene interactions and neighborhood topologically associated domains suggests breakdown of insulators contribute to ageing-associated diseases

FOXO3 longevity genotype attenuates the impact of hypertension on cerebral microinfarct risk

Circulating microRNA profile of long‐lived Okinawans identifies novel potential targets for optimizing lifespan and health span

Vascular endothelial growth factor receptor 1 gene ( FLT1 ) longevity variant increases lifespan by reducing mortality risk posed by hypertension

Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage

Incidence of Alzheimer's Disease in Men with Late-Life Hypertension Is Ameliorated by FOXO3 Longevity Genotype

FOXO3, a Resilience Gene: Impact on Lifespan, Healthspan, and Deathspan

Association of Methylenetetrahydrofolate Reductase Polymorphism C677T and Dietary Folate with the Risk of Cervical Dysplasia

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