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Tension on the linker gates the ATP-dependent release of dynein from microtubules

Nature communications, 2014-08, Vol.5 (1), p.4587-4587, Article 4587

2014

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Phase I Trial of DNA Methyltransferase Inhibitor Guadecitabine Combined with Cisplatin and Gemcitabine for Solid Malignancies Including Urothelial Carcinoma (SPIRE)

Clinical cancer research, 2021-04, Vol.27 (7), p.1882-1892

2021

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A Phase 1 Study Evaluating ASTX727 (decitabine and cedazuridine) and Venetoclax Combination Therapy in Newly Diagnosed AML Patients Unfit for Intensive Induction Chemotherapy

Blood, 2021-11, Vol.138 (Supplement 1), p.1245-1245

2021

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Abstract CT108: A first-in-human, Phase 1 study of ASTX029, a dual-mechanism inhibitor of ERK1/2, in relapsed/refractory solid tumors

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.CT108-CT108

2021

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A first-in-human, phase 1 study of ASTX029, a dual-mechanism inhibitor of ERK1/2, in relapsed/refractory solid tumors

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.9085-9085

2022

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Population Pharmacokinetics of Melphalan for Pediatric Patients Undergoing Hematopoietic Cell Transplantation

Journal of clinical pharmacology, 2022-07, Vol.62 (7), p.873-882

2022

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Determination of melphalan in human plasma by UPLC–UV method

Cancer chemotherapy and pharmacology, 2019-05, Vol.83 (5), p.905-910

2019

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The time is now: model-based dosing to optimize drug therapy

International journal of pharmacokinetics, 2017-11, Vol.2 (4), p.213-215

2017

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Abstract A072: Preliminary results of ASTX660, a novel non-peptidomimetic cIAP1/2 and XIAP antagonist, in 107 patients with solid tumors or lymphoma

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.A072-A072

2019

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Engineered Dynein Mutants Reveal Minimal Structural and Catalytic Requirements for Processive Motility

Biophysical journal, 2012-01, Vol.102 (3), p.38a-38a

2012

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Abstract CT066: Phase 1 study of MDM2 antagonist ASTX295 in patients with solid tumors with wild-type TP53

Cancer research (Chicago, Ill.), 2024-04, Vol.84 (7_Supplement), p.CT066-CT066

2024

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A Force Dependent Gating Mechanism Inhibits ATP Dependent Release of Dynein from Microtubules

Biophysical journal, 2013-01, Vol.104 (2), p.383a-383a

2013

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Plasma and Intracellular Pharmacokinetic (PK) Analysis of Fludarabine in Pediatric Allogeneic Hematopoietic Cell Transplant (alloHCT) Recipients

Biology of blood and marrow transplantation, 2016-03, Vol.22 (3), p.S253-S253

2016

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565 - Improved Population Pharmacokinetic Model for Busulfan in Neonates and Children Facilitated by a Web-Based Bayesian Tool for Dosing and Therapeutic Drug Monitoring

Biology of blood and marrow transplantation, 2017-03, Vol.23 (3), p.S395-S395

2017

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Improved Population Pharmacokinetic Model for Busulfan in Neonates and Children Facilitated by a Web-Based Bayesian Tool for Dosing and Therapeutic Drug Monitoring

Biology of blood and marrow transplantation, 2017-03, Vol.23 (3), p.S395-S395

2017

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Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients

Biology of blood and marrow transplantation, 2017-10, Vol.23 (10), p.1701-1713

2017

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Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Review

Journal of the American Heart Association, 2017-12, Vol.6 (12), p.n/a

2017

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The relationship between the quantitative extent of late gadolinium enhancement and burden of nonsustained ventricular tachycardia in hypertrophic cardiomyopathy: A delayed contrast‐enhanced magnetic resonance study

Journal of cardiovascular electrophysiology, 2019-05, Vol.30 (5), p.651-657

2019

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Probing High-order Protein Complexes Using Native Mass Spectrometry and Hydrogen/Deuterium Exchange Mass Spectrometry: A Case Study Using Fresh and Commercial Hemoglobin Samples

Journal of the American Society for Mass Spectrometry, 2024-08, Vol.35 (8), p.1921-1929

2024

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Peptide Oxidation Induced by Liquid–Solid Contact Electrification as Revealed in Liquid Microjunction-Surface Sampling Probe Mass Spectrometry

Analytical chemistry (Washington), 2023-06, Vol.95 (23), p.9060-9067

2023

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A millimeter water-in-oil droplet as an alternative back exchange prevention strategy for hydrogen/deuterium exchange mass spectrometry of peptides/proteins

Analyst (London), 2024-04, Vol.149 (8), p.2388-2398

2024

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Use of group IIB metal ions as charge carriers for collision‐induced dissociation of glycopeptide and glycan

Rapid communications in mass spectrometry, 2023-01, Vol.37 (2), p.e9424-n/a

2023

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CaptiveSpray Differential Ion Mobility Spectrometry Device with Enhanced Ion Transmission and Improved Resolving Power

Journal of the American Society for Mass Spectrometry, 2023-05, Vol.34 (5), p.820-825

2023

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Usefulness of 14-Day Holter for Detection of Nonsustained Ventricular Tachycardia in Patients With Hypertrophic Cardiomyopathy

The American journal of cardiology, 2016-10, Vol.118 (8), p.1258-1263

2016

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Tension on the linker gates the ATP-dependent release of dynein from microtubules

Phase I Trial of DNA Methyltransferase Inhibitor Guadecitabine Combined with Cisplatin and Gemcitabine for Solid Malignancies Including Urothelial Carcinoma (SPIRE)

Oral Decitabine/Cedazuridine Vs Intravenous Decitabine for Acute Myeloid Leukemia: Final Results of a Randomized, Crossover, Registration-Enabling, Pharmacokinetics Study

A Phase 1 Study Evaluating ASTX727 (decitabine and cedazuridine) and Venetoclax Combination Therapy in Newly Diagnosed AML Patients Unfit for Intensive Induction Chemotherapy

Abstract CT108: A first-in-human, Phase 1 study of ASTX029, a dual-mechanism inhibitor of ERK1/2, in relapsed/refractory solid tumors

A first-in-human, phase 1 study of ASTX029, a dual-mechanism inhibitor of ERK1/2, in relapsed/refractory solid tumors

Population Pharmacokinetics of Melphalan for Pediatric Patients Undergoing Hematopoietic Cell Transplantation

Determination of melphalan in human plasma by UPLC–UV method

The time is now: model-based dosing to optimize drug therapy

Abstract A072: Preliminary results of ASTX660, a novel non-peptidomimetic cIAP1/2 and XIAP antagonist, in 107 patients with solid tumors or lymphoma

Engineered Dynein Mutants Reveal Minimal Structural and Catalytic Requirements for Processive Motility

Abstract CT066: Phase 1 study of MDM2 antagonist ASTX295 in patients with solid tumors with wild-type TP53

A Force Dependent Gating Mechanism Inhibits ATP Dependent Release of Dynein from Microtubules

Plasma and Intracellular Pharmacokinetic (PK) Analysis of Fludarabine in Pediatric Allogeneic Hematopoietic Cell Transplant (alloHCT) Recipients

565 - Improved Population Pharmacokinetic Model for Busulfan in Neonates and Children Facilitated by a Web-Based Bayesian Tool for Dosing and Therapeutic Drug Monitoring

Improved Population Pharmacokinetic Model for Busulfan in Neonates and Children Facilitated by a Web-Based Bayesian Tool for Dosing and Therapeutic Drug Monitoring

Pharmacokinetics and Model-Based Dosing to Optimize Fludarabine Therapy in Pediatric Hematopoietic Cell Transplant Recipients

Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Review

The relationship between the quantitative extent of late gadolinium enhancement and burden of nonsustained ventricular tachycardia in hypertrophic cardiomyopathy: A delayed contrast‐enhanced magnetic resonance study

Probing High-order Protein Complexes Using Native Mass Spectrometry and Hydrogen/Deuterium Exchange Mass Spectrometry: A Case Study Using Fresh and Commercial Hemoglobin Samples

Peptide Oxidation Induced by Liquid–Solid Contact Electrification as Revealed in Liquid Microjunction-Surface Sampling Probe Mass Spectrometry

A millimeter water-in-oil droplet as an alternative back exchange prevention strategy for hydrogen/deuterium exchange mass spectrometry of peptides/proteins

Use of group IIB metal ions as charge carriers for collision‐induced dissociation of glycopeptide and glycan

CaptiveSpray Differential Ion Mobility Spectrometry Device with Enhanced Ion Transmission and Improved Resolving Power

Usefulness of 14-Day Holter for Detection of Nonsustained Ventricular Tachycardia in Patients With Hypertrophic Cardiomyopathy

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