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HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4

Journal of allergy and clinical immunology, 2017-08, Vol.140 (2), p.584-587.e8

2017

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Nitric Oxide Is a Volume Transmitter Regulating Postsynaptic Excitability at a Glutamatergic Synapse

Neuron (Cambridge, Mass.), 2008-11, Vol.60 (4), p.642-656

2008

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Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy

The Journal of neuroscience, 2013-03, Vol.33 (13), p.5626-5637

2013

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“Phenotypic” pharmacology: The influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology

Biochemical pharmacology, 2007-03, Vol.73 (6), p.737-751

2007

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Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells

Biochemical pharmacology, 2008-02, Vol.75 (4), p.942-955

2008

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Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.30315-30324

2002

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Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells

The Journal of biological chemistry, 1998-02, Vol.273 (9), p.5037-5046

1998

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Neuronal Ca2+ stores : activation and function

Trends in neurosciences (Regular ed.), 1995-07, Vol.18 (7), p.299-306

1995

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Role of Ca2+ Feedback on Single Cell Inositol 1,4,5-Trisphosphate Oscillations Mediated by G-protein-coupled Receptors

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.20753-20760

2003

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GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation

Biochemical pharmacology, 2023-10, Vol.216, p.115795-115795, Article 115795

2023

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Single-cell imaging of graded Ins(1,4,5)P3 production following G-protein-coupled-receptor activation

Biochemical journal, 2001-05, Vol.356 (Pt 1), p.137-142

2001

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Using the Flp-In™ T-Rex™ system to regulate GPCR expression

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.21

2011

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G protein-coupled receptor signalling in astrocytes in health and disease: A focus on metabotropic glutamate receptors

Biochemical pharmacology, 2012-08, Vol.84 (3), p.249-259

2012

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Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

Biochemical journal, 2001-11, Vol.359 (Pt 3), p.465-484

2001

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Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

Cellular signalling, 2018-11, Vol.51, p.86-98

2018

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Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.211

2011

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Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

Cardiovascular research, 2010-02, Vol.85 (3), p.424-433

2010

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Analysis of GPCR localization and trafficking

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.425

2011

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Study of GPCR-protein interactions by BRET

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.357

2011

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Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.373

2011

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Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.297

2011

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Radioligand binding methods for membrane preparations and intact cells

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.135

2011

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A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor

Biochimie, 2011-12, Vol.93 (12), p.2132-2138

2011

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G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling

Cardiovascular research, 2011-01, Vol.89 (1), p.193-203

2011

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Determining allosteric modulator mechanism of action: integration of radioligand binding and functional assay data

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.195

Langmead, Christopher J

2011

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HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4

Nitric Oxide Is a Volume Transmitter Regulating Postsynaptic Excitability at a Glutamatergic Synapse

Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy

“Phenotypic” pharmacology: The influence of cellular environment on G protein-coupled receptor antagonist and inverse agonist pharmacology

Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells

Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells

Differential Regulation of Muscarinic Acetylcholine Receptor-sensitive Polyphosphoinositide Pools and Consequences for Signaling in Human Neuroblastoma Cells

Neuronal Ca2+ stores : activation and function

Role of Ca2+ Feedback on Single Cell Inositol 1,4,5-Trisphosphate Oscillations Mediated by G-protein-coupled Receptors

GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation

Single-cell imaging of graded Ins(1,4,5)P3 production following G-protein-coupled-receptor activation

Using the Flp-In™ T-Rex™ system to regulate GPCR expression

G protein-coupled receptor signalling in astrocytes in health and disease: A focus on metabotropic glutamate receptors

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells

Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

Analysis of GPCR localization and trafficking

Study of GPCR-protein interactions by BRET

Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization

Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors

Radioligand binding methods for membrane preparations and intact cells

A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor

G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling

Determining allosteric modulator mechanism of action: integration of radioligand binding and functional assay data

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