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Biological function of Aβ peptides revealed by analysis of membrane-association properties: Implications for Azheimer's disease pathogenesis

Biochemical and biophysical research communications, 2024-11, Vol.734, p.150611, Article 150611

2024

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E22G Aβ40 fibril structure and kinetics illuminate how Aβ40 rather than Aβ42 triggers familial Alzheimer’s

Nature communications, 2024-08, Vol.15 (1), p.7045-16

2024

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Deciphering the Molecular Dance: Exploring the Dynamic Interplay Between Mouse Insulin B9–23 Peptides and their Variants

Biochemistry (Easton), 2024-09, Vol.63 (18), p.2245-2256

2024

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Understanding Osaka mutation polymorphic Aβ fibril response to static and oscillating electric fields: insights from computational modeling

Scientific reports, 2024-09, Vol.14 (1), p.22246-11, Article 22246

2024

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Amyloid-β oligomers trigger sex-dependent inhibition of GIRK channel activity in hippocampal neurons in mice

Science signaling, 2024-10, Vol.17 (856), p.eado4132

2024

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Characteristics and Transcriptomic Analysis of Cholinergic Neurons Derived from Induced Pluripotent Stem Cells with APP Mutation in Alzheimer's Disease

Journal of Alzheimer's disease, 2024-01, Vol.101 (2), p.637-649

2024

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Gene-variant specific effects of plasma amyloid-β levels in Swedish autosomal dominant Alzheimer disease

Alzheimer's research & therapy, 2024-09, Vol.16 (1), p.207-11, Article 207

2024

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DNAm scores for serum GDF15 and NT-proBNP levels associate with a range of traits affecting the body and brain

Clinical epigenetics, 2024-09, Vol.16 (1), p.124-15, Article 124

2024

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Metabolomic profiling identifies novel metabolites associated with cardiac dysfunction

Scientific reports, 2024-09, Vol.14 (1), p.20694-11, Article 20694

2024

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Prion protein prevents the inhibition of large-conductance calcium-activated potassium channel by Tau peptide K18 oligomers

Biochemical and biophysical research communications, 2024-11, Vol.734, p.150793, Article 150793

2024

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IL-7Rα on CD4 + T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis

Journal of neuroinflammation, 2024-10, Vol.21 (1), p.253-15, Article 253

2024

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A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability

mAbs, 2024-12, Vol.16 (1), p.2394230

2024

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Gene therapy in Aβ-induced cell and mouse models of Alzheimer's disease through compensating defective mitochondrial complex I function

Journal of translational medicine, 2024-08, Vol.22 (1), p.760-16

2024

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METTL14 inhibits Aβ1-42-induced neuronal injury through regulating the stability of CBLN4 mRNA in Alzheimer’s disease

Journal of bioenergetics and biomembranes, 2024-10, Vol.56 (5), p.495-504

2024

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Developing Topics

Alzheimer's & dementia, 2023-12, Vol.19 Suppl 24, p.e082763

2023

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SIRT1 Regulates Mitochondrial Damage in N2a Cells Treated with the Prion Protein Fragment 106-126 via PGC-1α-TFAM-Mediated Mitochondrial Biogenesis

International journal of molecular sciences, 2024-09, Vol.25 (17), p.9707

2024

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Levels of Amyloid Beta ( Aβ ) Expression in the Caenorhabditis elegans Neurons Influence the Onset and Severity of Neuronally Mediated Phenotypes

Cells (Basel, Switzerland), 2024-09, Vol.13 (18), p.1598

2024

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Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis

International journal of molecular sciences, 2024-08, Vol.25 (16), p.8768

2024

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ACE2 alleviates sepsis-induced cardiomyopathy through inhibiting M1 macrophage via NF-κB/STAT1 signals

Cell biology and toxicology, 2024-09, Vol.40 (1), p.82, Article 82

2024

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Structural and biochemical characterization of the C‐terminal region of the human RTEL1 helicase

Protein science, 2024-09, Vol.33 (9), p.e5093-n/a

2024

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Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes

Fluids and barriers of the CNS, 2024-09, Vol.21 (1), p.78-20, Article 78

2024

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GGAssembler: Precise and economical design and synthesis of combinatorial mutation libraries

Protein science, 2024-10, Vol.33 (10), p.e5169-n/a

2024

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AXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation

Signal transduction and targeted therapy, 2024-10, Vol.9 (1), p.281-17, Article 281

2024

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ACE2 Alleviates Endoplasmic Reticulum Stress and Protects against Pyroptosis by Regulating Ang1-7/Mas in Ventilator-Induced Lung Injury

Frontiers in bioscience (Landmark. Print), 2024-09, Vol.29 (9), p.334

2024

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Biological function of Aβ peptides revealed by analysis of membrane-association properties: Implications for Azheimer's disease pathogenesis

E22G Aβ40 fibril structure and kinetics illuminate how Aβ40 rather than Aβ42 triggers familial Alzheimer’s

Deciphering the Molecular Dance: Exploring the Dynamic Interplay Between Mouse Insulin B9–23 Peptides and their Variants

Understanding Osaka mutation polymorphic Aβ fibril response to static and oscillating electric fields: insights from computational modeling

Amyloid-β oligomers trigger sex-dependent inhibition of GIRK channel activity in hippocampal neurons in mice

Characteristics and Transcriptomic Analysis of Cholinergic Neurons Derived from Induced Pluripotent Stem Cells with APP Mutation in Alzheimer's Disease

Gene-variant specific effects of plasma amyloid-β levels in Swedish autosomal dominant Alzheimer disease

DNAm scores for serum GDF15 and NT-proBNP levels associate with a range of traits affecting the body and brain

Metabolomic profiling identifies novel metabolites associated with cardiac dysfunction

Prion protein prevents the inhibition of large-conductance calcium-activated potassium channel by Tau peptide K18 oligomers

IL-7Rα on CD4 + T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis

A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability

Gene therapy in Aβ-induced cell and mouse models of Alzheimer's disease through compensating defective mitochondrial complex I function

The angiotensin‐(1‐7)/MasR axis improves pneumonia caused by Pseudomonas aeruginosa: Extending the therapeutic window for antibiotic therapy

METTL14 inhibits Aβ1-42-induced neuronal injury through regulating the stability of CBLN4 mRNA in Alzheimer’s disease

Developing Topics

SIRT1 Regulates Mitochondrial Damage in N2a Cells Treated with the Prion Protein Fragment 106-126 via PGC-1α-TFAM-Mediated Mitochondrial Biogenesis

Levels of Amyloid Beta ( Aβ ) Expression in the Caenorhabditis elegans Neurons Influence the Onset and Severity of Neuronally Mediated Phenotypes

Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis

ACE2 alleviates sepsis-induced cardiomyopathy through inhibiting M1 macrophage via NF-κB/STAT1 signals

Structural and biochemical characterization of the C‐terminal region of the human RTEL1 helicase

Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes

GGAssembler: Precise and economical design and synthesis of combinatorial mutation libraries

AXIN1 boosts antiviral response through IRF3 stabilization and induced phase separation

ACE2 Alleviates Endoplasmic Reticulum Stress and Protects against Pyroptosis by Regulating Ang1-7/Mas in Ventilator-Induced Lung Injury

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