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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Journal of the American Chemical Society, 2020-09, Vol.142 (38), p.16240-16253

2020

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Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides

Angewandte Chemie (International ed.), 2014-09, Vol.53 (38), p.10114-10118

International ed. in English, 2014

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A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome

Nature medicine, 2021-03, Vol.27 (3), p.536-545

2021

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Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy

Nucleic acid therapeutics, 2017-06, Vol.27 (3), p.130

2017

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Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide

Molecules (Basel, Switzerland), 2016-11, Vol.21 (11), p.1582-1582

2016

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Manipulation of gene expression in zebrafish using caged circular morpholino oligomers

Nucleic acids research, 2012-11, Vol.40 (21), p.11155

2012

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A chemical view of oligonucleotides for exon skipping and related drug applications

Nucleic acid therapeutics, 2014-02, Vol.24 (1), p.37

2014

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Use of Translation Blocking Morpholinos for Gene Knockdown in Giardia lamblia

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1565, p.123

2017

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Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides

Nucleic acid therapeutics, 2015-10, Vol.25 (5), p.275

2015

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Enhancing the speed of morpholino-DNA biosensor by electrokinetic concentration of DNA in a microfluidic chip

Biosensors & bioelectronics, 2015-10, Vol.72, p.87-94

2015

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Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro

Analytical biochemistry, 2016-09, Vol.509, p.41-45

2016

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Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

Viruses, 2012-11, Vol.4 (11), p.2806-2830

2012

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Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity

Human molecular genetics, 2014-12, Vol.23 (23), p.6302-6317

2014

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Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice

Molecular therapy, 2014-07, Vol.22 (7), p.1333-1341

2014

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Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

Nature protocols, 2011-12, Vol.6 (12), p.2035-2049

2011

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Use of vivo-morpholinos for control of protein expression in the adult rat brain

Journal of neuroscience methods, 2012-01, Vol.203 (2), p.354-360

2012

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Using Morpholinos to Control Gene Expression

Current Protocols in Nucleic Acid Chemistry, 2017-03, Vol.68 (1), p.4.30.1-4.30.29

Moulton, Jon D.

2017

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Synthesis and Initial Characterization of a Selective, Pseudo‐irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer

ChemMedChem, 2021-05, Vol.16 (9), p.1427-1437

2021

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Dual Functional Roles of Molecular Beacon as a MicroRNA Detector and Inhibitor

The Journal of biological chemistry, 2017-03, Vol.292 (9), p.3568-3580

2017

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Antibiotics present and future

FEBS letters, 2014-01, Vol.588 (1), p.1-2

Altman, S.

2014

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Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

Scientific reports, 2015-06, Vol.5 (1), p.11632, Article 11632

2015

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Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (3), p.1445-1447

2012

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Silencing of FABP3 leads to apoptosis-induced mitochondrial dysfunction and stimulates Wnt signaling in zebrafish

Molecular medicine reports, 2013-09, Vol.8 (3), p.806-812

2013

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Eteplirsen in the treatment of Duchenne muscular dystrophy

Drug design, development and therapy, 2017-01, Vol.11, p.533-545

2017

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Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus ® ), in human plasma using LC-MS/MS

Bioanalysis, 2017-05, Vol.9 (10), p.827-839

2017

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Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Sequential Gene Silencing Using Wavelength-Selective Caged Morpholino Oligonucleotides

A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome

Identification of a Peptide for Systemic Brain Delivery of a Morpholino Oligonucleotide in Mouse Models of Spinal Muscular Atrophy

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2'-O-Methyl Mixmer Antisense Oligonucleotide

Manipulation of gene expression in zebrafish using caged circular morpholino oligomers

A chemical view of oligonucleotides for exon skipping and related drug applications

Use of Translation Blocking Morpholinos for Gene Knockdown in Giardia lamblia

Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides

Enhancing the speed of morpholino-DNA biosensor by electrokinetic concentration of DNA in a microfluidic chip

Knockdown of gene expression by antisense morpholino oligos in preimplantation mouse embryos cultured in vitro

Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections

Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity

Effective Dystrophin Restoration by a Novel Muscle-Homing Peptide–Morpholino Conjugate in Dystrophin-Deficient mdx Mice

Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

Use of vivo-morpholinos for control of protein expression in the adult rat brain

Using Morpholinos to Control Gene Expression

Synthesis and Initial Characterization of a Selective, Pseudo‐irreversible Inhibitor of Human Butyrylcholinesterase as PET Tracer

Dual Functional Roles of Molecular Beacon as a MicroRNA Detector and Inhibitor

Antibiotics present and future

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

Development of an efficient method for phosphorodiamidate bond formation by using inorganic salts

Silencing of FABP3 leads to apoptosis-induced mitochondrial dysfunction and stimulates Wnt signaling in zebrafish

Eteplirsen in the treatment of Duchenne muscular dystrophy

Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus ® ), in human plasma using LC-MS/MS

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