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Application of the message-address concept in the design of highly potent and selective non-peptide .delta. opioid receptor antagonists

Journal of medicinal chemistry, 1988-02, Vol.31 (2), p.281-282

1988

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Role of spacer and address components in peptidomimetic .delta.-opioid receptor antagonists related to naltrindole

Journal of medicinal chemistry, 1991-05, Vol.34 (5), p.1715-1720

1991

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Suppression by dynorphin A-(1–13) of the expression of opiate withdrawal and tolerance in mice

European journal of pharmacology, 1992-10, Vol.221 (2-3), p.223-226

1992

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Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone

Life sciences (1973), 1992, Vol.50 (20), p.1491-1495

1992

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Role of the spacer in conferring .kappa. opioid receptor selectivity to bivalent ligands related to norbinaltorphimine

Journal of medicinal chemistry, 1991-04, Vol.34 (4), p.1292-1296

1991

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Opioid agonist and antagonist activities of morphindoles related to naltrindole

Journal of medicinal chemistry, 1992-11, Vol.35 (23), p.4325-4329

1992

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A highly selective δ1-opioid receptor antagonist : 7-benzylidenenaltrexone

European journal of pharmacology, 1992-07, Vol.218 (1), p.195-196

1992

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Synthesis and .kappa.-opioid antagonist selectivity of a norbinaltorphimine congener. Identification of the address moiety required for .kappa.-antagonist activity

Journal of medicinal chemistry, 1993-08, Vol.36 (16), p.2412-2415

1993

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Binaltorphimine and nor-binaltorphimine, potent and selective k-opioid receptor antagonists

Life sciences (1973), 1987-03, Vol.40 (13), p.1287-1292

1987

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The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone

European journal of pharmacology, 1981-04, Vol.70 (4), p.445-451

1981

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A selective .delta.1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for .delta.1 opioid receptor agonists and antagonists

Journal of medicinal chemistry, 1993-08, Vol.36 (17), p.2572-2574

1993

Volltextzugriff (PDF)

Enkephalin antinociception in mice is mediated by δ1- and δ2-opioid receptors in the brain and spinal cord, respectively

European journal of pharmacology, 1993-09, Vol.242 (2), p.145-150

1993

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Selective kappa antagonist properties of nor-binaltorphimine in the rat mes seizure model

Life sciences (1973), 1989, Vol.44 (10), p.661-665

1989

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Activities of morphinone and N-(cyclopropylmethyl)normorphinone at opioid receptors

Journal of medicinal chemistry, 1984-10, Vol.27 (10), p.1361-1363

1984

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Bimorphinans as highly selective, potent .kappa. opioid receptor antagonists

Journal of medicinal chemistry, 1987-02, Vol.30 (2), p.238-239

1987

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Stereochemical studies on medicinal agents. 31. Only one pharmacophore is required for the .kappa. opioid antagonist selectivity of norbinaltorphimine

Journal of medicinal chemistry, 1988-07, Vol.31 (7), p.1344-1347

1988

Volltextzugriff (PDF)

Quantitative studies on the antagonism by naloxone of some narcotic and narcotic‐antagonist analgesics

British journal of pharmacology, 1970-07, Vol.39 (3), p.627-638

1970

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The type of analgesic-receptor interaction involved in certain analgesic assays

European journal of pharmacology, 1971-09, Vol.16 (1), p.63-66

1971

Volltextzugriff (PDF)

Involvement of spinal kappa opiod receptors in the antagonistic effect of dynorphins on morphine antinociception

Life sciences (1973), 1991, Vol.48 (15), p.1447-1453

1991

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Activity of N-methyl-.alpha.- and -.beta.-funaltrexamine at opioid receptors

Journal of medicinal chemistry, 1986-08, Vol.29 (8), p.1551-1553

1986

Volltextzugriff (PDF)

The potentiation of spinal analgesia by leucine enkephalin

European journal of pharmacology, 1980-02, Vol.61 (4), p.381-383

1980

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Effect of fluoxetine hydrochloride (Lilly 110140), a specific inhibitor of serotonin uptake, on morphine analgesia and the development of tolerance

Life sciences (1973), 1977-12, Vol.21 (12), p.1807-1811

1977

Volltextzugriff (PDF)

Cellular Adaptation to Morphine in Rats

Science (American Association for the Advancement of Science), 1961-03, Vol.133 (3457), p.1018-1019

Takemori, A. E.

1961

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The effect of biogenic amine modifiers on morphine analgesia and its antagonism by naloxone

European journal of pharmacology, 1976-02, Vol.35 (2), p.285-292

1976

Volltextzugriff (PDF)

Differential effects on morphine analgesia and naloxone antagonism by biogenic amine modifiers

Life sciences (1973), 1975-07, Vol.17 (1), p.21-27

1975

Volltextzugriff (PDF)

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Application of the message-address concept in the design of highly potent and selective non-peptide .delta. opioid receptor antagonists

Role of spacer and address components in peptidomimetic .delta.-opioid receptor antagonists related to naltrindole

Suppression by dynorphin A-(1–13) of the expression of opiate withdrawal and tolerance in mice

Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone

Role of the spacer in conferring .kappa. opioid receptor selectivity to bivalent ligands related to norbinaltorphimine

Opioid agonist and antagonist activities of morphindoles related to naltrindole

A highly selective δ1-opioid receptor antagonist : 7-benzylidenenaltrexone

Synthesis and .kappa.-opioid antagonist selectivity of a norbinaltorphimine congener. Identification of the address moiety required for .kappa.-antagonist activity

Binaltorphimine and nor-binaltorphimine, potent and selective k-opioid receptor antagonists

The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone

A selective .delta.1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for .delta.1 opioid receptor agonists and antagonists

Enkephalin antinociception in mice is mediated by δ1- and δ2-opioid receptors in the brain and spinal cord, respectively

Selective kappa antagonist properties of nor-binaltorphimine in the rat mes seizure model

Activities of morphinone and N-(cyclopropylmethyl)normorphinone at opioid receptors

Bimorphinans as highly selective, potent .kappa. opioid receptor antagonists

Stereochemical studies on medicinal agents. 31. Only one pharmacophore is required for the .kappa. opioid antagonist selectivity of norbinaltorphimine

Quantitative studies on the antagonism by naloxone of some narcotic and narcotic‐antagonist analgesics

The type of analgesic-receptor interaction involved in certain analgesic assays

Involvement of spinal kappa opiod receptors in the antagonistic effect of dynorphins on morphine antinociception

Activity of N-methyl-.alpha.- and -.beta.-funaltrexamine at opioid receptors

The potentiation of spinal analgesia by leucine enkephalin

Effect of fluoxetine hydrochloride (Lilly 110140), a specific inhibitor of serotonin uptake, on morphine analgesia and the development of tolerance

Cellular Adaptation to Morphine in Rats

The effect of biogenic amine modifiers on morphine analgesia and its antagonism by naloxone

Differential effects on morphine analgesia and naloxone antagonism by biogenic amine modifiers

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