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Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy

The FEBS journal, 2017-01, Vol.284 (1), p.42-55

2017

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Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications

Trends in cell biology, 2016-05, Vol.26 (5), p.352-366

2016

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Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis

Blood, 2010-03, Vol.115 (12), p.2449-2457

2010

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Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth

Cancer research (Chicago, Ill.), 2016-09, Vol.76 (17), p.4981-4993

2016

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Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation

Journal of cell science, 2010-11, Vol.123 (21), p.3796-3807

2010

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Spatial and Temporal Expression of Heparan Sulfate in Mouse Development Regulates FGF and FGF Receptor Assembly

The Journal of cell biology, 2003-11, Vol.163 (3), p.637-648

2003

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Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration

Genes & development, 2004-09, Vol.18 (18), p.2231-2236

2004

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HSulf-1 and HSulf-2 Are Potent Inhibitors of Myeloma Tumor Growth in Vivo

The Journal of biological chemistry, 2005-12, Vol.280 (48), p.40066-40073

2005

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Transmembrane and Extracellular Domains of Syndecan-1 Have Distinct Functions in Regulating Lung Epithelial Migration and Adhesion

The Journal of biological chemistry, 2012-10, Vol.287 (42), p.34927-34935

2012

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Molecular interactions of syndecans during development

Seminars in cell & developmental biology, 2001-04, Vol.12 (2), p.107-116

Rapraeger, Alan C

2001

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Role of Heparan Sulfate as a Tissue-Specific Regulator of FGF-4 and FGF Receptor Recognition

The Journal of cell biology, 2001-11, Vol.155 (5), p.845-857

2001

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Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin

The Journal of cell biology, 2006-09, Vol.174 (7), p.1097-1106

2006

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Cell-surface Heparan Sulfate Proteoglycans Potentiate Chordin Antagonism of Bone Morphogenetic Protein Signaling and Are Necessary for Cellular Uptake of Chordin

The Journal of biological chemistry, 2004-12, Vol.279 (49), p.51289-51297

2004

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Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

Science (American Association for the Advancement of Science), 1991-06, Vol.252 (5013), p.1705-1708

1991

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Fibroblast growth factor receptor-1 mediates the inhibition of endothelial cell proliferation and the promotion of skeletal myoblast differentiation by SPARC: A role for protein kinase A

Journal of cellular biochemistry, 2003-10, Vol.90 (2), p.408-423

2003

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Syndecan-3 and Syndecan-4 Specifically Mark Skeletal Muscle Satellite Cells and Are Implicated in Satellite Cell Maintenance and Muscle Regeneration

Developmental biology, 2001-11, Vol.239 (1), p.79-94

2001

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Two Hierarchies of FGF-2 Signaling in Heparin: Mitogenic Stimulation and High-Affinity Binding/Receptor Transphosphorylation

Biochemistry (Easton), 1996-08, Vol.35 (34), p.11131-11141

1996

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Interaction of Syndecan and α6β4 Integrin Cytoplasmic Domains

The Journal of biological chemistry, 2010-04, Vol.285 (18), p.13569-13579

2010

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The cell surface proteoglycan syndecan-1 mediates fibroblast growth factor-2 binding and activity

Journal of cellular physiology, 1998-03, Vol.174 (3), p.310-321

1998

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Heparan sulfate proteoglycan and FGF receptor target basic FGF to different intracellular destinations

Journal of cell science, 1993-08, Vol.105 (4), p.1085-1093

1993

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Post-Transcriptional Regulation of Syndecan-1 Expression by cAMP in Peritoneal Macrophages

The Journal of cell biology, 1993-08, Vol.122 (4), p.941-950

1993

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Identification of an Adhesion Site within the Syndecan-4 Extracellular Protein Domain

The Journal of biological chemistry, 1997-05, Vol.272 (20), p.12901-12904

1997

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Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4

The Journal of biological chemistry, 1993-11, Vol.268 (32), p.23906-23914

1993

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Role of FGFs in skeletal muscle and limb development

Molecular reproduction and development, 1994-09, Vol.39 (1), p.90-101

1994

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The coordinated regulation of heparan sulfate, syndecans and cell behavior

Current opinion in cell biology, 1993-10, Vol.5 (5), p.844-853

Rapraeger, Alan C.

1993

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Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy

Stress-Induced EGFR Trafficking: Mechanisms, Functions, and Therapeutic Implications

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis

Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth

Syndecan-1 couples the insulin-like growth factor-1 receptor to inside-out integrin activation

Spatial and Temporal Expression of Heparan Sulfate in Mouse Development Regulates FGF and FGF Receptor Assembly

Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration

HSulf-1 and HSulf-2 Are Potent Inhibitors of Myeloma Tumor Growth in Vivo

Transmembrane and Extracellular Domains of Syndecan-1 Have Distinct Functions in Regulating Lung Epithelial Migration and Adhesion

Molecular interactions of syndecans during development

Role of Heparan Sulfate as a Tissue-Specific Regulator of FGF-4 and FGF Receptor Recognition

Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin

Cell-surface Heparan Sulfate Proteoglycans Potentiate Chordin Antagonism of Bone Morphogenetic Protein Signaling and Are Necessary for Cellular Uptake of Chordin

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

Fibroblast growth factor receptor-1 mediates the inhibition of endothelial cell proliferation and the promotion of skeletal myoblast differentiation by SPARC: A role for protein kinase A

Syndecan-3 and Syndecan-4 Specifically Mark Skeletal Muscle Satellite Cells and Are Implicated in Satellite Cell Maintenance and Muscle Regeneration

Two Hierarchies of FGF-2 Signaling in Heparin: Mitogenic Stimulation and High-Affinity Binding/Receptor Transphosphorylation

Interaction of Syndecan and α6β4 Integrin Cytoplasmic Domains

The cell surface proteoglycan syndecan-1 mediates fibroblast growth factor-2 binding and activity

Heparan sulfate proteoglycan and FGF receptor target basic FGF to different intracellular destinations

Post-Transcriptional Regulation of Syndecan-1 Expression by cAMP in Peritoneal Macrophages

Identification of an Adhesion Site within the Syndecan-4 Extracellular Protein Domain

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4

Role of FGFs in skeletal muscle and limb development

The coordinated regulation of heparan sulfate, syndecans and cell behavior

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