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Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions

Journal of the American Chemical Society, 2017-07, Vol.139 (27), p.9120-9123

2017

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature (London), 2015-04, Vol.520 (7549), p.683-687

2015

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Mechanism, Reactivity, and Selectivity in Palladium-Catalyzed Redox-Relay Heck Arylations of Alkenyl Alcohols

Journal of the American Chemical Society, 2014-02, Vol.136 (5), p.1960-1967

2014

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Chemical genomics reveals histone deacetylases are required for core regulatory transcription

Nature communications, 2019-07, Vol.10 (1), p.3004-12, Article 3004

2019

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Computational Exploration of Zinc Binding Groups for HDAC Inhibition

Journal of organic chemistry, 2013-05, Vol.78 (10), p.5051-5055

2013

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Strategic elements in computer-assisted retrosynthesis: A case study of the pupukeanane natural products

Tetrahedron, 2022-01, Vol.104, p.132584, Article 132584

2022

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Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma

Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (46), p.13162-13167

2016

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Investigating the Nature of Palladium Chain-Walking in the Enantioselective Redox-Relay Heck Reaction of Alkenyl Alcohols

Journal of organic chemistry, 2014-12, Vol.79 (24), p.11841-11850

2014

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SET-Induced Biaryl Cross-Coupling: An SRN1 Reaction

Journal of organic chemistry, 2014-03, Vol.79 (6), p.2771-2774

2014

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Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (14), p.5620-5625

2011

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The Increasingly Complex Mechanism of HMG-CoA Reductase

Accounts of chemical research, 2013-11, Vol.46 (11), p.2416-2426

2013

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Diastereoselectivity in Lewis-Acid-Catalyzed Mukaiyama Aldol Reactions: A DFT Study

Journal of the American Chemical Society, 2012-09, Vol.134 (36), p.14973-14981

2012

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Prediction of Enantioselectivity in Rhodium Catalyzed Hydrogenations

Journal of the American Chemical Society, 2009-01, Vol.131 (2), p.410-411

2009

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Treatment of Niemann–Pick Type C Disease by Histone Deacetylase Inhibitors

Neurotherapeutics, 2013-10, Vol.10 (4), p.688-697

2013

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HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts

Journal of lipid research, 2021-01, Vol.62, p.100114-100114, Article 100114

2021

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Toward Selective Histone Deacetylase Inhibitor Design: Homology Modeling, Docking Studies, and Molecular Dynamics Simulations of Human Class I Histone Deacetylases

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.6936-6947

2005

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Synthesis and Conformation−Activity Relationships of the Peptide Isosteres of FK228 and Largazole

Journal of the American Chemical Society, 2009-03, Vol.131 (8), p.2900-2905

2009

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Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann−Pick Type C Disease Therapeutics

Journal of medicinal chemistry, 2010-07, Vol.53 (14), p.5281-5289

2010

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Synthesis and Histone Deacetylase Inhibitory Activity of Largazole Analogs: Alteration of the Zinc-Binding Domain and Macrocyclic Scaffold

Organic letters, 2009-03, Vol.11 (6), p.1301-1304

2009

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Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole

Bioorganic & medicinal chemistry, 2015-08, Vol.23 (15), p.5061-5074

2015

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Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes

PloS one, 2012-12, Vol.7 (12), p.e50186-e50186

2012

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Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders

Current topics in medicinal chemistry, 2009-02, Vol.9 (3), p.257

2009

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Internal and External Stereoisomers of Squaraine Rotaxane Endoperoxide: Synthesis, Chemical Differences, and Structural Revision

Journal of organic chemistry, 2014-02, Vol.79 (3), p.1120-1130

2014

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Molecular Modeling of the Reaction Pathway and Hydride Transfer Reactions of HMG-CoA Reductase

Biochemistry (Easton), 2012-10, Vol.51 (40), p.7983-7995

2012

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Hydroxyl Radical's Role in the Remediation of a Common Herbicide, 2,4-Dichlorophenoxyacetic Acid (2,4-D)

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2004-12, Vol.108 (50), p.10925-10933

2004

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Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Mechanism, Reactivity, and Selectivity in Palladium-Catalyzed Redox-Relay Heck Arylations of Alkenyl Alcohols

Chemical genomics reveals histone deacetylases are required for core regulatory transcription

Computational Exploration of Zinc Binding Groups for HDAC Inhibition

Strategic elements in computer-assisted retrosynthesis: A case study of the pupukeanane natural products

Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma

Investigating the Nature of Palladium Chain-Walking in the Enantioselective Redox-Relay Heck Reaction of Alkenyl Alcohols

SET-Induced Biaryl Cross-Coupling: An SRN1 Reaction

Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

The Increasingly Complex Mechanism of HMG-CoA Reductase

Diastereoselectivity in Lewis-Acid-Catalyzed Mukaiyama Aldol Reactions: A DFT Study

Prediction of Enantioselectivity in Rhodium Catalyzed Hydrogenations

Treatment of Niemann–Pick Type C Disease by Histone Deacetylase Inhibitors

HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts

Toward Selective Histone Deacetylase Inhibitor Design: Homology Modeling, Docking Studies, and Molecular Dynamics Simulations of Human Class I Histone Deacetylases

Synthesis and Conformation−Activity Relationships of the Peptide Isosteres of FK228 and Largazole

Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann−Pick Type C Disease Therapeutics

Synthesis and Histone Deacetylase Inhibitory Activity of Largazole Analogs: Alteration of the Zinc-Binding Domain and Macrocyclic Scaffold

Modular synthesis and biological activity of pyridyl-based analogs of the potent Class I Histone Deacetylase Inhibitor Largazole

Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes

Inhibition of histone deacetylases: a pharmacological approach to the treatment of non-cancer disorders

Internal and External Stereoisomers of Squaraine Rotaxane Endoperoxide: Synthesis, Chemical Differences, and Structural Revision

Molecular Modeling of the Reaction Pathway and Hydride Transfer Reactions of HMG-CoA Reductase

Hydroxyl Radical's Role in the Remediation of a Common Herbicide, 2,4-Dichlorophenoxyacetic Acid (2,4-D)

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