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Activation of the JNK signaling pathway: Breaking the brake on apoptosis

BioEssays, 2003-01, Vol.25 (1), p.17-24

Lin, Anning

2003

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Role of JNK activation in apoptosis： A double-edged sword

Cell research, 2005, Vol.15 (1), p.36-42

2005

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The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

Immunity (Cambridge, Mass.), 2021-06, Vol.54 (6), p.1168-1185.e8

2021

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Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (45), p.E10682-E10691

2018

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Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (31), p.9644-9649

2015

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Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006534-e1006534

2017

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BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages

eLife, 2020-12, Vol.9

2020

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Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (44), p.18886-18891

2010

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Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

Diabetes (New York, N.Y.), 2011-02, Vol.60 (2), p.486-495

2011

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Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis

Cell host & microbe, 2008-10, Vol.4 (4), p.350-361

2008

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JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

Molecular cell, 2004-02, Vol.13 (3), p.329-340

2004

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Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

The Journal of biological chemistry, 2008-07, Vol.283 (30), p.20754-20760

2008

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Cell, 1995-06, Vol.81 (7), p.1147-1157

1995

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SIP30 Is Regulated by ERK in Peripheral Nerve Injury-induced Neuropathic Pain

The Journal of biological chemistry, 2009-10, Vol.284 (44), p.30138-30147

2009

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The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma

Cancer research (Chicago, Ill.), 2006-02, Vol.66 (4), p.2264-2270

2006

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Opposing Effects of Jun Kinase and p38 Mitogen-Activated Protein Kinases on Cardiomyocyte Hypertrophy

Molecular and Cellular Biology, 1998-06, Vol.18 (6), p.3518-3526

1998

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Cyclic AMP Inhibits p38 Activation via CREB-Induced Dynein Light Chain

Molecular and Cellular Biology, 2006-02, Vol.26 (4), p.1223-1234

2006

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Phosphorylation of Bcl-associated death protein (Bad) by erythropoietin-activated c-Jun N-terminal protein kinase 1 contributes to survival of erythropoietin-dependent cells

The international journal of biochemistry & cell biology, 2011-03, Vol.43 (3), p.409-415

2011

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Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (23), p.10984-10991

2005

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Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

Science (American Association for the Advancement of Science), 1994-12, Vol.266 (5191), p.1719-1723

1994

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Involvement of c‐Jun N‐terminal kinase in amyloid precursor protein‐mediated neuronal cell death

Journal of neurochemistry, 2003-02, Vol.84 (4), p.864-877

2003

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Activation of c‐Jun NH2‐terminal kinase is required for gemcitabine's cytotoxic effect in human lung cancer H1299 cells

FEBS letters, 2005-12, Vol.579 (29), p.6681-6687

2005

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Constitutively Active Mitogen-activated Protein Kinase Kinase 6 (MKK6) or Salicylate Induces Spontaneous 3T3-L1 Adipogenesis

The Journal of biological chemistry, 1999-12, Vol.274 (50), p.35630-35638

1999

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Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

Cell death and differentiation, 1999-10, Vol.6 (10), p.987-991

1999

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Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

Cell, 1992-09, Vol.70 (5), p.777-789

1992

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Activation of the JNK signaling pathway: Breaking the brake on apoptosis

Role of JNK activation in apoptosis： A double-edged sword

The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia

Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching

Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK

BAD inactivation exacerbates rheumatoid arthritis pathology by promoting survival of sublining macrophages

Retinoic acid regulates bone morphogenic protein signal duration by promoting the degradation of phosphorylated Smad1

Selective Inactivation of c-Jun NH2-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis

JNK Suppresses Apoptosis via Phosphorylation of the Proapoptotic Bcl-2 Family Protein BAD

Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

SIP30 Is Regulated by ERK in Peripheral Nerve Injury-induced Neuropathic Pain

The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma

Opposing Effects of Jun Kinase and p38 Mitogen-Activated Protein Kinases on Cardiomyocyte Hypertrophy

Cyclic AMP Inhibits p38 Activation via CREB-Induced Dynein Light Chain

Phosphorylation of Bcl-associated death protein (Bad) by erythropoietin-activated c-Jun N-terminal protein kinase 1 contributes to survival of erythropoietin-dependent cells

Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7

Differential Activation of ERK and JNK Mitogen-Activated Protein Kinases by Raf-1 and MEKK

Involvement of c‐Jun N‐terminal kinase in amyloid precursor protein‐mediated neuronal cell death

Activation of c‐Jun NH2‐terminal kinase is required for gemcitabine's cytotoxic effect in human lung cancer H1299 cells

Constitutively Active Mitogen-activated Protein Kinase Kinase 6 (MKK6) or Salicylate Induces Spontaneous 3T3-L1 Adipogenesis

Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

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