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On the Discovery and Development of Pimavanserin: A Novel Drug Candidate for Parkinson’s Psychosis

Neurochemical research, 2014-10, Vol.39 (10), p.2008-2017

2014

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Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Journal of medicinal chemistry, 2005-12, Vol.48 (24), p.7517-7519

2005

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Optimization of isochromanone based urotensin II receptor agonists

Bioorganic & medicinal chemistry, 2010-07, Vol.18 (13), p.4844-4854

2010

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Identification of novel subtype selective RAR agonists

Biochemical pharmacology, 2005-12, Vol.71 (1), p.156-162

2005

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Stereoselective Epoxidation of Phe-Gly and Phe-Phe Vinyl Isosteres

Journal of organic chemistry, 1994-03, Vol.59 (5), p.1139-1148

1994

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The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons

Naunyn-Schmiedeberg's archives of pharmacology, 1993-04, Vol.347 (4), p.353-362

1993

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Characterization of the Binding Site of the Histamine H3 Receptor. 1. Various Approaches to the Synthesis of 2-(1H-Imidazol-4-yl)cyclopropylamine and Histaminergic Activity of (1R,2R)- and (1S,2S)-2-(1H-Imidazol-4-yl)- cyclopropylamine

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1115-1122

1999

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1 The Chemistry and Biochemistry of C-Nucleosides and C-Arylglycosides

Progress in Medicinal Chemistry, 1985, Vol.22, p.1-65

1985

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Base-Catalyzed cyclization of N-propargylamides to oxazoles

Journal of heterocyclic chemistry, 1989-03, Vol.26 (2), p.269-275

1989

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8-Hydroxy-2-(dipropylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

Journal of medicinal chemistry, 1981-08, Vol.24 (8), p.921-923

1981

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3-Heteroaryl-Substituted Quinuclidin-3-ol and Quinuclidin-2-ene Derivatives as Muscarinic Antagonists. Synthesis and Structure-Activity Relationships

Journal of medicinal chemistry, 1995-02, Vol.38 (3), p.473-487

1995

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(R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41) : two novel 5-HT1A receptor agonists

European journal of pharmacology, 1993-01, Vol.231 (1), p.69-76

1993

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Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.4950-4953

2002

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Synthesis and pharmacology of the enantiomers of cis-7-hydroxy-3-methyl-2-(dipropylamino)tetralin

Journal of medicinal chemistry, 1990-10, Vol.33 (10), p.2925-2929

1990

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Syntheses of 5-, 7-, and 8-methoxy-3-methyl-2-tetralones

Journal of organic chemistry, 1986-12, Vol.51 (26), p.5252-5258

1986

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Animal Carotenoids. 32. Carotenoids of Mytilus edulis (Edible Mussel)

Acta chemica Scandinavica (Copenhagen. 1989), 1988, Vol.42b, p.495-503

1988

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Electron Transfer Reactions. XV. On the Mechanism of the Radical Cation Catalyzed Diels-Alder Dimerization of 1,3-Cyclohexadiene

Acta chemica Scandinavica (Copenhagen. 1989), 1988, Vol.42b, p.336-338

1988

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On the Discovery and Development of Pimavanserin: A Novel Drug Candidate for Parkinson’s Psychosis

Discovery of a Potent, Orally Available, and Isoform-Selective Retinoic Acid β2 Receptor Agonist

Optimization of isochromanone based urotensin II receptor agonists

Identification of novel subtype selective RAR agonists

Stereoselective Epoxidation of Phe-Gly and Phe-Phe Vinyl Isosteres

The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons

Characterization of the Binding Site of the Histamine H3 Receptor. 1. Various Approaches to the Synthesis of 2-(1H-Imidazol-4-yl)cyclopropylamine and Histaminergic Activity of (1R,2R)- and (1S,2S)-2-(1H-Imidazol-4-yl)- cyclopropylamine

1 The Chemistry and Biochemistry of C-Nucleosides and C-Arylglycosides

Base-Catalyzed cyclization of N-propargylamides to oxazoles

8-Hydroxy-2-(dipropylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

3-Heteroaryl-Substituted Quinuclidin-3-ol and Quinuclidin-2-ene Derivatives as Muscarinic Antagonists. Synthesis and Structure-Activity Relationships

(R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41) : two novel 5-HT1A receptor agonists

Discovery of the First Nonpeptide Agonist of the GPR14/Urotensin-II Receptor: 3-(4-Chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954)

Synthesis and pharmacology of the enantiomers of cis-7-hydroxy-3-methyl-2-(dipropylamino)tetralin

Syntheses of 5-, 7-, and 8-methoxy-3-methyl-2-tetralones

Animal Carotenoids. 32. Carotenoids of Mytilus edulis (Edible Mussel)

Electron Transfer Reactions. XV. On the Mechanism of the Radical Cation Catalyzed Diels-Alder Dimerization of 1,3-Cyclohexadiene

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