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Toward a Better Testing Paradigm for Developmental Neurotoxicity: OECD Efforts and Regulatory Considerations

Biology (Basel, Switzerland), 2021-01, Vol.10 (2), p.86

2021

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From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation

Toxicological sciences, 2017-11, Vol.160 (1), p.121-135

2017

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International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity Testing

Toxicological sciences, 2019-01, Vol.167 (1), p.45-57

2019

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Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity

Neurotoxicology and teratology, 2015-11, Vol.52 (Pt B), p.181-193

2015

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Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set

Neurotoxicology (Park Forest South), 2012-10, Vol.33 (5), p.1048-1057

2012

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Concentration–response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

Archives of toxicology, 2020-02, Vol.94 (2), p.469-484

2020

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Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century

Neurotoxicology (Park Forest South), 2010-08, Vol.31 (4), p.331-350

2010

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Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures

Toxicological sciences, 2021-04, Vol.180 (2), p.295-312

2021

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Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons

The Journal of pharmacology and experimental therapeutics, 2011-01, Vol.336 (1), p.197-205

2011

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Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs

Environmental health perspectives, 2005-02, Vol.113 (2), p.123-136

2005

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Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates

Journal of biomolecular screening, 2016-06, Vol.21 (5), p.510-519

2016

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A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing

Neurotoxicology (Park Forest South), 2017-05, Vol.60, p.280-292

2017

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Assessment of Chemical Effects on Neurite Outgrowth in PC12 cells Using High Content Screening

Toxicological sciences, 2008-09, Vol.105 (1), p.106-118

2008

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Developmental neurotoxicity testing: A path forward

Congenital anomalies, 2012-09, Vol.52 (3), p.140-146

2012

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Development of a High-Throughput Screening Assay for Chemical Effects on Proliferation and Viability of Immortalized Human Neural Progenitor Cells

Toxicological sciences, 2008-09, Vol.105 (1), p.119-133

2008

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Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: State of the science

Neurotoxicology and teratology, 2010-01, Vol.32 (1), p.4-15

2010

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Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture

Environmental health perspectives, 2011-09, Vol.119 (9), p.1239-1246

2011

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Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells

Neurotoxicology (Park Forest South), 2012-12, Vol.33 (6), p.1499-1510

2012

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Glufosinate binds N-methyl-d-aspartate receptors and increases neuronal network activity in vitro

Neurotoxicology (Park Forest South), 2014-12, Vol.45, p.38-47

2014

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Assaying Spontaneous Network Activity and Cellular Viability Using Multi-well Microelectrode Arrays

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1601, p.153

2017

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Application of Microelectrode Array Approaches to Neurotoxicity Testing and Screening

Advances in neurobiology, 2019, Vol.22, p.275-297

2019

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Identification of neurotoxicology (NT)/developmental neurotoxicology (DNT) adverse outcome pathways and key event linkages with in vitro DNT screening assays

Neurotoxicology (Park Forest South), 2023-12, Vol.99, p.184-194

2023

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Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment

Toxicology and applied pharmacology, 2018-09, Vol.354, p.24-39

2018

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The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency

Toxicological sciences, 2019-06, Vol.169 (2), p.317-332

2019

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Effects of pyrethroids on voltage-sensitive calcium channels: a critical evaluation of strengths, weaknesses, data needs, and relationship to assessment of cumulative neurotoxicity

Toxicology and Applied Pharmacology, 2004-04, Vol.196 (2), p.303-318

2004

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Toward a Better Testing Paradigm for Developmental Neurotoxicity: OECD Efforts and Regulatory Considerations

From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation

International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity Testing

Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity

Evaluation of multi-well microelectrode arrays for neurotoxicity screening using a chemical training set

Concentration–response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

Microelectrode arrays: A physiologically based neurotoxicity testing platform for the 21st century

Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures

Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons

Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs

Characterization of Early Cortical Neural Network Development in Multiwell Microelectrode Array Plates

A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing

Assessment of Chemical Effects on Neurite Outgrowth in PC12 cells Using High Content Screening

Developmental neurotoxicity testing: A path forward

Development of a High-Throughput Screening Assay for Chemical Effects on Proliferation and Viability of Immortalized Human Neural Progenitor Cells

Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: State of the science

Additivity of Pyrethroid Actions on Sodium Influx in Cerebrocortical Neurons in Primary Culture

Comparison of chemical-induced changes in proliferation and apoptosis in human and mouse neuroprogenitor cells

Glufosinate binds N-methyl-d-aspartate receptors and increases neuronal network activity in vitro

Assaying Spontaneous Network Activity and Cellular Viability Using Multi-well Microelectrode Arrays

Application of Microelectrode Array Approaches to Neurotoxicity Testing and Screening

Identification of neurotoxicology (NT)/developmental neurotoxicology (DNT) adverse outcome pathways and key event linkages with in vitro DNT screening assays

Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment

The Next Generation Blueprint of Computational Toxicology at the U.S. Environmental Protection Agency

Effects of pyrethroids on voltage-sensitive calcium channels: a critical evaluation of strengths, weaknesses, data needs, and relationship to assessment of cumulative neurotoxicity

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