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Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells

Cell stem cell, 2014-04, Vol.14 (4), p.535-548

2014

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Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

The Journal of experimental medicine, 2010-12, Vol.207 (13), p.2817-2830

2010

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Ex vivo generation of platelet products from human iPS cells

Inflammation and Regeneration, 2020-12, Vol.40 (1), p.1-30, Article 30

2020

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Three-dimensional microchannel reflecting cell size distribution for on-chip production of platelet-like particles

Microfluidics and nanofluidics, 2021-04, Vol.25 (4), Article 36

2021

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A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility

Nature communications, 2024-03, Vol.15 (1), p.2588-2588, Article 2588

2024

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Development of platelet replacement therapy using human induced pluripotent stem cells

Development, growth & differentiation, 2021-02, Vol.63 (2), p.178-186

2021

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Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell–derived megakaryocytes

Experimental hematology, 2013-08, Vol.41 (8), p.742-748

2013

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iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

Stem cell reports, 2020-01, Vol.14 (1), p.49-59

2020

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Microfluidic Bioreactor Made of Cyclo-Olefin Polymer for Observing On-Chip Platelet Production

Micromachines (Basel), 2021-10, Vol.12 (10), p.1253

2021

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Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

The Journal of clinical investigation, 2013-09, Vol.123 (9), p.3802-3814

2013

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Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin β1-ILK-β-catenin-JUN axis

Stem cell research, 2021-05, Vol.53, p.102287-102287, Article 102287

2021

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Natural Killer Cell Activities Against iPSCs-Derived HLA-Knockout Platelets and Megakaryocytes Reveal Perfect Rejection Profiles for Allotransfusion

Blood, 2016-12, Vol.128 (22), p.3841-3841

2016

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Defective flow space limits the scaling up of turbulence bioreactors for platelet generation

Communications engineering, 2024-12, Vol.3 (1), p.77-12

2024

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Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells

Haematologica (Roma), 2020-05, Vol.105 (5), p.e216-e220

2020

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Production and nonclinical evaluation of an autologous iPSC–derived platelet product for the iPLAT1 clinical trial

Blood advances, 2022-12, Vol.6 (23), p.6056-6069

2022

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Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells

Stem cell reports, 2013-12, Vol.1 (6), p.499-508

2013

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Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells

Blood advances, 2017-02, Vol.1 (7), p.468-476

2017

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Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

Cell, 2018-07, Vol.174 (3), p.636-648.e18

2018

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iPSC-Derived Mesenchymal Stem Cells Supports the Ex Vivo expansion of Human Hematopoietic Stem and Progenitor Cells Via Sterile Inflammation Pathway

Blood, 2023-11, Vol.142 (Supplement 1), p.2680-2680

2023

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Centrosomal function assessment in human sperm using heterologous ICSI with rabbit eggs: A new male factor infertility assay

Molecular reproduction and development, 2004-03, Vol.67 (3), p.360-365

2004

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Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Blood, 2018-11, Vol.132 (Supplement 1), p.3845-3845

2018

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Use of Mammalian Eggs for Assessment of Human Sperm Function: Molecular and Cellular Analyses of Fertilization by Intracytoplasmic Sperm Injection

American journal of reproductive immunology (1989), 2004-04, Vol.51 (4), p.290-293

2004

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Isolated Torsion of the Distal Part of the Fallopian Tube in a Premenarcheal 12 Year Old Girl: A Case Report

The Tohoku Journal of Experimental Medicine, 2004, Vol.202(3), pp.239-243

2004

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The First-in-Human Clinical Trial of iPSC-Derived Platelets (iPLAT1): Autologous Transfusion to an Aplastic Anemia Patient with Alloimmune Platelet Transfusion Refractoriness

Blood, 2021-11, Vol.138 (Supplement 1), p.351-351

2021

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Expandable Megakaryocyte Cell Lines Enable Clinically Applicable Generation of Platelets from Human Induced Pluripotent Stem Cells

Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study

Ex vivo generation of platelet products from human iPS cells

Three-dimensional microchannel reflecting cell size distribution for on-chip production of platelet-like particles

A let-7 microRNA-RALB axis links the immune properties of iPSC-derived megakaryocytes with platelet producibility

Development of platelet replacement therapy using human induced pluripotent stem cells

Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell–derived megakaryocytes

iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity

Microfluidic Bioreactor Made of Cyclo-Olefin Polymer for Observing On-Chip Platelet Production

Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin β1-ILK-β-catenin-JUN axis

Natural Killer Cell Activities Against iPSCs-Derived HLA-Knockout Platelets and Megakaryocytes Reveal Perfect Rejection Profiles for Allotransfusion

Defective flow space limits the scaling up of turbulence bioreactors for platelet generation

Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells

Production and nonclinical evaluation of an autologous iPSC–derived platelet product for the iPLAT1 clinical trial

Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells

Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

iPSC-Derived Mesenchymal Stem Cells Supports the Ex Vivo expansion of Human Hematopoietic Stem and Progenitor Cells Via Sterile Inflammation Pathway

Centrosomal function assessment in human sperm using heterologous ICSI with rabbit eggs: A new male factor infertility assay

Environmental Cell-Matrix Adhesion Modulates Pluripotent Stem Cell Fate Toward Definitive Hemogenic Endothelium and Hematopoietic Progenitor Cells

Use of Mammalian Eggs for Assessment of Human Sperm Function: Molecular and Cellular Analyses of Fertilization by Intracytoplasmic Sperm Injection

Isolated Torsion of the Distal Part of the Fallopian Tube in a Premenarcheal 12 Year Old Girl: A Case Report

The First-in-Human Clinical Trial of iPSC-Derived Platelets (iPLAT1): Autologous Transfusion to an Aplastic Anemia Patient with Alloimmune Platelet Transfusion Refractoriness

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