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Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors

Journal of clinical oncology, 2005-02, Vol.23 (5), p.965-972

2005

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Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

Annals of oncology, 2006-05, Vol.17 (5), p.866-873

2006

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Pegylated liposomal doxorubicin: Proof of principle using preclinical animal models and pharmacokinetic studies

Seminars in oncology, 2004-12, Vol.31 (6 Suppl 13), p.16-35

2004

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The Ras-Raf-MEK-ERK pathway in the treatment of cancer

Oncology research and treatment, 2002-12, Vol.25 (6), p.511-518

2002

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Dose-escalated treosulphan in combination with cyclophosphamide as a new preparative regimen for allogeneic haematopoietic stem cell transplantation in patients with an increased risk for regimen-related complications

Bone marrow transplantation (Basingstoke), 2005-02, Vol.35 (3), p.233-241

2005

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Clinical Phase I Dose Escalation and Pharmacokinetic Study of High-Dose Chemotherapy with Treosulfan and Autologous Peripheral Blood Stem Cell Transplantation in Patients with Advanced Malignancies

Clinical cancer research, 2000-11, Vol.6 (11), p.4209-4216

2000

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Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin in advanced Non-Small Cell Lung Cancer (NSCLC) patient

Pneumologie (Stuttgart, Germany), 2016, Vol.70 (S 01)

2016

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The epidermal growth factor receptor tyrosine kinase inhibitor gefitinib sensitizes colon cancer cells to irinotecan

Anti-cancer drugs, 2005-11, Vol.16 (10), p.1099-1108

2005

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Clinical pharmacokinetics of intravenous treosulfan in patients with advanced solid tumors

Cancer chemotherapy and pharmacology, 1998, Vol.42 (2), p.99-104

1998

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Femoral head necrosis in three patients with relapsed ovarian cancer receiving high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation

Bone marrow transplantation (Basingstoke), 2003-03, Vol.31 (6), p.487-491

2003

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Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

British journal of cancer, 1999-12, Vol.81 (8), p.1304-1310

1999

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Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

Cancer chemotherapy and pharmacology, 2000, Vol.45 (6), p.483-488

2000

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Interleukin-3, interleukin-8, FMLP and C5a enhance the release of leukotrienes from neutrophils of patients with atopic dermatitis

Immunology, 1991-05, Vol.73 (1), p.83-87

1991

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Conversion of leukotriene A4 by neutrophils and platelets from patients with atopic dermatitis

Immunology, 1991-12, Vol.74 (4), p.689-695

1991

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Cetirizine exerts anti-inflammatory effects on human neutrophils

International archives of allergy and immunology, 1996-01, Vol.110 (1), p.52-56

1996

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Dual effect of ammonium persulfate on the generation of leukotrienes from human neutrophil granulocytes

International archives of allergy and immunology, 1996-08, Vol.110 (4), p.318-324

1996

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Cellular determinants of resistance to indolocarbazole analogue 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13(beta-D-glucopyranosyl)- 5H-indolo[2,3-alpha]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506), a novel potent topoisomerase I inhibitor, in multidrug-resistant human tumor cells

Oncology research, 1997, Vol.9 (9), p.485

1997

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Immunosuppressive agents enhance the cytokine-induced priming of inflammatory cells

International archives of allergy and immunology, 1995-05, Vol.107 (1-3), p.259

1995

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Analysis of leukotriene B4 metabolism in human promyelocytic HL-60 cells

Biochemical journal, 1991-10, Vol.279 (1), p.283-288

1991

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Differential increase in 12-HETE release and CD29/CD49f expression of platelets from normal donors and from patients with atopic dermatitis by Staphylococcus aureus

International archives of allergy and immunology, 1992-01, Vol.98 (4), p.339-342

1992

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Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502

Inflammation, 1996-02, Vol.20 (1), p.57-70

1996

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Interactions of cytokines and lipid mediators in acute and chronic inflammation

International archives of allergy and immunology, 1995-05, Vol.107 (1-3), p.383-384

1995

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Effect of the PAF-receptor antagonist SM-12502 on human platelets

Inflammation, 1996-02, Vol.20 (1), p.71-85

1996

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Cyclosporin A and Tacrolimus - A Comparison Of Different Immunoassays and HPLC: 159

Therapeutic drug monitoring, 2005-04, Vol.27 (2), p.252

2005

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Prognostic factors and jaw and renal complications among multiple myeloma patients treated with zoledronic acid

American journal of hematology, 2011-01, Vol.86 (1), p.25-30

2011

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Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors

Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

Pegylated liposomal doxorubicin: Proof of principle using preclinical animal models and pharmacokinetic studies

The Ras-Raf-MEK-ERK pathway in the treatment of cancer

Dose-escalated treosulphan in combination with cyclophosphamide as a new preparative regimen for allogeneic haematopoietic stem cell transplantation in patients with an increased risk for regimen-related complications

Clinical Phase I Dose Escalation and Pharmacokinetic Study of High-Dose Chemotherapy with Treosulfan and Autologous Peripheral Blood Stem Cell Transplantation in Patients with Advanced Malignancies

Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin in advanced Non-Small Cell Lung Cancer (NSCLC) patient

The epidermal growth factor receptor tyrosine kinase inhibitor gefitinib sensitizes colon cancer cells to irinotecan

Clinical pharmacokinetics of intravenous treosulfan in patients with advanced solid tumors

Femoral head necrosis in three patients with relapsed ovarian cancer receiving high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation

Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

Investigation of bioavailability and pharmacokinetics of treosulfan capsules in patients with relapsed ovarian cancer

Interleukin-3, interleukin-8, FMLP and C5a enhance the release of leukotrienes from neutrophils of patients with atopic dermatitis

Conversion of leukotriene A4 by neutrophils and platelets from patients with atopic dermatitis

Cetirizine exerts anti-inflammatory effects on human neutrophils

Dual effect of ammonium persulfate on the generation of leukotrienes from human neutrophil granulocytes

Cellular determinants of resistance to indolocarbazole analogue 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13(beta-D-glucopyranosyl)- 5H-indolo[2,3-alpha]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (NB-506), a novel potent topoisomerase I inhibitor, in multidrug-resistant human tumor cells

Immunosuppressive agents enhance the cytokine-induced priming of inflammatory cells

Analysis of leukotriene B4 metabolism in human promyelocytic HL-60 cells

Differential increase in 12-HETE release and CD29/CD49f expression of platelets from normal donors and from patients with atopic dermatitis by Staphylococcus aureus

Inhibition of leukotriene formation and IL-8 release by the paf-receptor antagonist SM-12502

Interactions of cytokines and lipid mediators in acute and chronic inflammation

Effect of the PAF-receptor antagonist SM-12502 on human platelets

Cyclosporin A and Tacrolimus - A Comparison Of Different Immunoassays and HPLC: 159

Prognostic factors and jaw and renal complications among multiple myeloma patients treated with zoledronic acid

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