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Phenotypic and Functional Heterogeneity of Monocytes and Macrophages

International journal of molecular sciences, 2023-10, Vol.24 (19), p.14525

Hellman, Lars

2023

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Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability

Frontiers in immunology, 2018-10, Vol.9, p.2387-2387

2018

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Fc receptors for immunoglobulins and their appearance during vertebrate evolution

PloS one, 2014-05, Vol.9 (5), p.e96903-e96903

2014

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Mast Cell and Basophil Granule Proteases - In Vivo Targets and Function

Frontiers in immunology, 2022-07, Vol.13, p.918305-918305

2022

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Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5147

2019

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The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells

International journal of molecular sciences, 2024-01, Vol.25 (1), p.356

2024

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Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3

International journal of molecular sciences, 2020-01, Vol.21 (2), p.651

2020

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The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases

International journal of molecular sciences, 2021-10, Vol.22 (20), p.10975

2021

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The extended cleavage specificity of human thrombin

PloS one, 2012-02, Vol.7 (2), p.e31756-e31756

2012

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Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution

PloS one, 2015-11, Vol.10 (11), p.e0143091-e0143091

2015

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Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

Frontiers in immunology, 2017-12, Vol.8, p.1749-1749

2017

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Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

PloS one, 2018-04, Vol.13 (4), p.e0195077-e0195077

2018

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rMCP-2, the Major Rat Mucosal Mast Cell Protease, an Analysis of Its Extended Cleavage Specificity and Its Potential Role in Regulating Intestinal Permeability by the Cleavage of Cell Adhesion and Junction Proteins

PloS one, 2015-06, Vol.10 (6), p.e0131720-e0131720

2015

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Extended cleavage specificities of two mast cell chymase-related proteases and one granzyme B-like protease from the platypus, a monotreme

International journal of molecular sciences, 2020-01, Vol.21 (1), p.319

2020

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The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin

PloS one, 2015-06, Vol.10 (6), p.e0129511-e0129511

2015

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Identification of the Major Protein Components of Human and Cow Saliva

International journal of molecular sciences, 2023-12, Vol.24 (23), p.16838

2023

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Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G

The Journal of immunology (1950), 2017-02, Vol.198 (4), p.1474-1483

2017

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Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8546

2020

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Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5818

2022

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Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma

Scientific reports, 2023-09, Vol.13 (1), p.16261-16261, Article 16261

2023

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Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution

PloS one, 2016-05, Vol.11 (5), p.e0154886-e0154886

2016

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Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

The Journal of biological chemistry, 2014-01, Vol.289 (1), p.237-250

2014

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Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Virulence, 2018-12, Vol.9 (1), p.879-894

2018

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Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases

International journal of molecular sciences, 2021-11, Vol.22 (23), p.12627

2021

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Regulation of IgE homeostasis, and the identification of potential targets for therapeutic intervention

Biomedicine & pharmacotherapy, 2007-01, Vol.61 (1), p.34-49

Hellman, Lars

2007

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Phenotypic and Functional Heterogeneity of Monocytes and Macrophages

Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability

Fc receptors for immunoglobulins and their appearance during vertebrate evolution

Mast Cell and Basophil Granule Proteases - In Vivo Targets and Function

Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity

The Extended Cleavage Specificity of Channel Catfish Granzyme-like II, A Highly Specific Elastase, Expressed by Natural Killer-like Cells

Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3

The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases

The extended cleavage specificity of human thrombin

Granule Associated Serine Proteases of Hematopoietic Cells - An Analysis of Their Appearance and Diversification during Vertebrate Evolution

Tracing the Origins of IgE, Mast Cells, and Allergies by Studies of Wild Animals

Extended cleavage specificity of human neutrophil cathepsin G: A low activity protease with dual chymase and tryptase-type specificities

rMCP-2, the Major Rat Mucosal Mast Cell Protease, an Analysis of Its Extended Cleavage Specificity and Its Potential Role in Regulating Intestinal Permeability by the Cleavage of Cell Adhesion and Junction Proteins

Extended cleavage specificities of two mast cell chymase-related proteases and one granzyme B-like protease from the platypus, a monotreme

The Importance of Exosite Interactions for Substrate Cleavage by Human Thrombin

Identification of the Major Protein Components of Human and Cow Saliva

Highly Selective Cleavage of Cytokines and Chemokines by the Human Mast Cell Chymase and Neutrophil Cathepsin G

Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells

Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation

Single-cell transcriptomics delineates the immune cell landscape in equine lower airways and reveals upregulation of FKBP5 in horses with asthma

Asp-ase Activity of the Opossum Granzyme B Supports the Role of Granzyme B as Part of Anti-Viral Immunity Already during Early Mammalian Evolution

Mast Cell Chymase Degrades the Alarmins Heat Shock Protein 70, Biglycan, HMGB1, and Interleukin-33 (IL-33) and Limits Danger-induced Inflammation

Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines

Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases

Regulation of IgE homeostasis, and the identification of potential targets for therapeutic intervention

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