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Pomegranate Juice and Pomegranate Extract Do Not Impair Oral Clearance of Flurbiprofen in Human Volunteers: Divergence From In Vitro Results

Clinical pharmacology and therapeutics, 2012-11, Vol.92 (5), p.651-657

2012

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Pharmacokinetic and Pharmacodynamic Interactions Between Zolpidem and Caffeine

Clinical pharmacology and therapeutics, 2007-07, Vol.82 (1), p.54-62

2007

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In Vitro Approaches to Predicting Drug Interactions In Vivo

Biochemical pharmacology, 1998, Vol.55 (2), p.113-122

1998

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Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram

Drug metabolism and disposition, 2001-08, Vol.29 (8), p.1102

2001

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Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir

Journal of clinical pharmacology, 1998-02, Vol.38 (2), p.106-111

1998

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Short-Term Clarithromycin Administration Impairs Clearance and Enhances Pharmacodynamic Effects of Trazodone but Not of Zolpidem

Clinical pharmacology and therapeutics, 2009-06, Vol.85 (6), p.644-650

2009

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O- and N-demethylation of Venlafaxine In Vitro by Human Liver Microsomes and by Microsomes from cDNA-Transfected Cells: Effect of Metabolic Inhibitors and SSRI Antidepressants

Neuropsychopharmacology (New York, N.Y.), 1999-05, Vol.20 (5), p.480-490

1999

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Dose-Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans

Journal of clinical pharmacology, 1997-08, Vol.37 (8), p.693-703

1997

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Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo

The Journal of pharmacology and experimental therapeutics, 1994-03, Vol.268 (3), p.1278

1994

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Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants

Journal of clinical psychopharmacology, 1995-04, Vol.15 (2), p.125-131

1995

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Alprazolam-ritonavir interaction: Implications for product labeling

Clinical pharmacology and therapeutics, 2000-04, Vol.67 (4), p.335-341

2000

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Multiple Human Cytochromes Contribute to Biotransformation of Dextromethorphan In-vitro: Role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

Journal of pharmacy and pharmacology, 1998-09, Vol.50 (9), p.997-1004

1998

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Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations

British journal of clinical pharmacology, 1999-07, Vol.48 (1), p.89-97

1999

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Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

The Journal of pharmacology and experimental therapeutics, 1996-02, Vol.276 (2), p.370

1996

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Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents

Journal of clinical pharmacology, 1996-09, Vol.36 (9), p.783-791

1996

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Comparative kinetics and dynamics of zaleplon, zolpidem, and placebo

Clinical pharmacology and therapeutics, 1998-11, Vol.64 (5), p.553-561

1998

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Inhibitors of alprazolam metabolism in vitro: effect of serotonin‐ reuptake‐inhibitor antidepressants, ketoconazole and quinidine

British journal of clinical pharmacology, 1994-07, Vol.38 (1), p.23-31

1994

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Five Distinct Human Cytochromes Mediate Amitriptyline N-Demethylation In Vitro: Dominance of CYP 2C19 and 3A4

Journal of clinical pharmacology, 1998-02, Vol.38 (2), p.112-121

1998

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Ketoconazole inhibition of triazolam and alprazolam clearance: Differential kinetic and dynamic consequences

Clinical pharmacology and therapeutics, 1998-09, Vol.64 (3), p.237-247

1998

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Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects

Biological psychiatry (1969), 1999-09, Vol.46 (6), p.839-849

1999

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N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.592

1995

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Differential impairment of triazolam and zolpidem clearance by ritonavir

Journal of acquired immune deficiency syndromes (1999), 2000-06, Vol.24 (2), p.129-136

2000

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Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro : cytochromes mediating transformation, and P450-3A4 inhibitory actions

Psychopharmacologia, 1999-07, Vol.145 (1), p.113-122

1999

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Relative Contribution of CYP3A to Amitriptyline Clearance in Humans: In Vitro and In Vivo Studies

Journal of clinical pharmacology, 2001-10, Vol.41 (10), p.1043-1054

2001

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Population Pharmacokinetics of Methylphenidate in Children with Attention-Deficit Hyperactivity Disorder

Journal of clinical pharmacology, 1999-08, Vol.39 (8), p.775-785

1999

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Pomegranate Juice and Pomegranate Extract Do Not Impair Oral Clearance of Flurbiprofen in Human Volunteers: Divergence From In Vitro Results

Pharmacokinetic and Pharmacodynamic Interactions Between Zolpidem and Caffeine

In Vitro Approaches to Predicting Drug Interactions In Vivo

Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram

Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir

Short-Term Clarithromycin Administration Impairs Clearance and Enhances Pharmacodynamic Effects of Trazodone but Not of Zolpidem

O- and N-demethylation of Venlafaxine In Vitro by Human Liver Microsomes and by Microsomes from cDNA-Transfected Cells: Effect of Metabolic Inhibitors and SSRI Antidepressants

Dose-Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans

Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo

Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants

Alprazolam-ritonavir interaction: Implications for product labeling

Multiple Human Cytochromes Contribute to Biotransformation of Dextromethorphan In-vitro: Role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents

Comparative kinetics and dynamics of zaleplon, zolpidem, and placebo

Inhibitors of alprazolam metabolism in vitro: effect of serotonin‐ reuptake‐inhibitor antidepressants, ketoconazole and quinidine

Five Distinct Human Cytochromes Mediate Amitriptyline N-Demethylation In Vitro: Dominance of CYP 2C19 and 3A4

Ketoconazole inhibition of triazolam and alprazolam clearance: Differential kinetic and dynamic consequences

Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects

N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors

Differential impairment of triazolam and zolpidem clearance by ritonavir

Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro : cytochromes mediating transformation, and P450-3A4 inhibitory actions

Relative Contribution of CYP3A to Amitriptyline Clearance in Humans: In Vitro and In Vivo Studies

Population Pharmacokinetics of Methylphenidate in Children with Attention-Deficit Hyperactivity Disorder

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