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SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models

Journal for immunotherapy of cancer, 2023-10, Vol.11 (10), p.e007572

2023

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854 SGN-B7H4V, a novel, investigational vedotin antibody-drug conjugate directed to the T cell checkpoint ligand B7-H4, shows promising activity in preclinical models

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A895-A895

2021

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Suppression of FVIII Inhibitor Formation in Hemophilic Mice by Delivery of Transgene Modified Apoptotic Fibroblasts

Molecular therapy, 2010-01, Vol.18 (1), p.214-222

2010

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KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells

Blood, 2000-02, Vol.95 (4), p.1151-1157

2000

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Abstract 50: Targeting Sialyl-Thomsen nouveau (STn) antigen with the SGN-STNV antibody-drug conjugate is effective in preclinical studies

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.50-50

2021

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CCR11 Is a Functional Receptor for the Monocyte Chemoattractant Protein Family of Chemokines

The Journal of biological chemistry, 2000-03, Vol.275 (13), p.9550-9556

2000

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Abstract 2469: Brentuximab vedotin-mediated immunogenic cell death

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2469-2469

2015

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Abstract 1542: Generation of an antibody-drug conjugate-optimized TLR 7/8 agonist payload

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1542-1542

2023

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Abstract 4994: SEA-CD40: from bench to bedside

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4994-4994

2016

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Incomplete restoration of Mpl expression in the mpl−/− mouse produces partial correction of the stem cell–repopulating defect and paradoxical thrombocytosis

Blood, 2009-02, Vol.113 (8), p.1778-1785

2009

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Abstract 2472: SEA-CD40, a sugar engineered non-fucosylated anti-CD40 antibody with improved immune activating capabilities

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.2472-2472

2015

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Abstract 1766: SGN-ALPV a novel, investigational vedotin ADC demonstrates highly effective targeting of oncofetal phosphatases ALPP and ALPPL2 in preclinical models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1766-1766

2022

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Phosphorylation Of The Cytoplasmic Tyrosine Residues Of c-Mpl Is Not Required To Preserve Intact Receptor Dependent Hematopoietic Stem Cell Survival Signaling

Blood, 2013-11, Vol.122 (21), p.3679-3679

2013

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A sugar engineered non-fucosylated anti-CD40 antibody, SEA-CD40, with enhanced immune stimulatory activity alone and in combination with immune checkpoint inhibitors

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.3074-3074

2015

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Abstract 1281: SGN-B7H4V shows immunomodulatory activity through induction of immunogenic cell death

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.1281-1281

2022

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Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells

Molecular therapy, 2011-10, Vol.19 (10), p.1896-1904

2011

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Suppression of the Immune Response to Human FVIII with FVIII Transgene Modified Tolerogenic Dendritic Cells in Hemophilia A Mice (89.42)

The Journal of immunology (1950), 2009-04, Vol.182 (1_Supplement), p.89-89.42

2009

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Suppression of the Immune Responses to Factor VIII in the Hemophilia A Mice by Delivery of Transgene Modified Apoptotic Syngeneic Fibroblasts (89.36)

The Journal of immunology (1950), 2009-04, Vol.182 (1_Supplement), p.89-89.36

2009

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Suppression of the Immune Response to Human FVIII with FVIII Transgene Modified Tolerogenic Dendritic Cells in Hemophilic Mice

Blood, 2008-11, Vol.112 (11), p.591-591

2008

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Proteomic analysis of the androgen receptor via MS-compatible purification of biotinylated protein on streptavidin resin

Proteomics (Weinheim), 2012-01, Vol.12 (1), p.43-53

2012

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Macrophage-derived chemokine is localized to thymic medullary epithelial cells and is a chemoattractant for CD3(+), CD4(+), CD8(low) thymocytes

Blood, 1999-09, Vol.94 (6), p.1890-1898

1999

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Induction of Tolerance to FVIII in Hemophilic Mice by Delivery of Apoptotic Syngeneic Fibroblasts Expressing a FVIII Transgene

Blood, 2006-11, Vol.108 (11), p.768-768

2006

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Reduction of inhibitor titres by infusion of FVIII gene transduced tolerogenic dendritic cells in haemophilic mice

Haemophilia : the official journal of the World Federation of Hemophilia, 2009-03, Vol.15 (2), p.634-634

2009

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Profile of human macrophage transcripts: insights into macrophage biology and identification of novel chemokines

Journal of leukocyte biology, 1998-07, Vol.64 (1), p.49-54

1998

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Macrophage-Derived Chemokine Is Localized to Thymic Medullary Epithelial Cells and Is a Chemoattractant for CD3+, CD4+, CD8low Thymocytes

Blood, 1999-09, Vol.94 (6), p.1890-1898

1999

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SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models

854 SGN-B7H4V, a novel, investigational vedotin antibody-drug conjugate directed to the T cell checkpoint ligand B7-H4, shows promising activity in preclinical models

Suppression of FVIII Inhibitor Formation in Hemophilic Mice by Delivery of Transgene Modified Apoptotic Fibroblasts

KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells

Abstract 50: Targeting Sialyl-Thomsen nouveau (STn) antigen with the SGN-STNV antibody-drug conjugate is effective in preclinical studies

CCR11 Is a Functional Receptor for the Monocyte Chemoattractant Protein Family of Chemokines

Abstract 2469: Brentuximab vedotin-mediated immunogenic cell death

Abstract 1542: Generation of an antibody-drug conjugate-optimized TLR 7/8 agonist payload

Abstract 4994: SEA-CD40: from bench to bedside

Incomplete restoration of Mpl expression in the mpl−/− mouse produces partial correction of the stem cell–repopulating defect and paradoxical thrombocytosis

Abstract 2472: SEA-CD40, a sugar engineered non-fucosylated anti-CD40 antibody with improved immune activating capabilities

Abstract 1766: SGN-ALPV a novel, investigational vedotin ADC demonstrates highly effective targeting of oncofetal phosphatases ALPP and ALPPL2 in preclinical models

Phosphorylation Of The Cytoplasmic Tyrosine Residues Of c-Mpl Is Not Required To Preserve Intact Receptor Dependent Hematopoietic Stem Cell Survival Signaling

A sugar engineered non-fucosylated anti-CD40 antibody, SEA-CD40, with enhanced immune stimulatory activity alone and in combination with immune checkpoint inhibitors

Abstract 1281: SGN-B7H4V shows immunomodulatory activity through induction of immunogenic cell death

Suppression of the Immune Response to FVIII in Hemophilia A Mice by Transgene Modified Tolerogenic Dendritic Cells

Suppression of the Immune Response to Human FVIII with FVIII Transgene Modified Tolerogenic Dendritic Cells in Hemophilia A Mice (89.42)

Suppression of the Immune Responses to Factor VIII in the Hemophilia A Mice by Delivery of Transgene Modified Apoptotic Syngeneic Fibroblasts (89.36)

Suppression of the Immune Response to Human FVIII with FVIII Transgene Modified Tolerogenic Dendritic Cells in Hemophilic Mice

Proteomic analysis of the androgen receptor via MS-compatible purification of biotinylated protein on streptavidin resin

Macrophage-derived chemokine is localized to thymic medullary epithelial cells and is a chemoattractant for CD3(+), CD4(+), CD8(low) thymocytes

Induction of Tolerance to FVIII in Hemophilic Mice by Delivery of Apoptotic Syngeneic Fibroblasts Expressing a FVIII Transgene

Reduction of inhibitor titres by infusion of FVIII gene transduced tolerogenic dendritic cells in haemophilic mice

Profile of human macrophage transcripts: insights into macrophage biology and identification of novel chemokines

Macrophage-Derived Chemokine Is Localized to Thymic Medullary Epithelial Cells and Is a Chemoattractant for CD3+, CD4+, CD8low Thymocytes

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