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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice

Journal of neuroinflammation, 2021-09, Vol.18 (1), p.222-222, Article 222

2021

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An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis

PLoS computational biology, 2019-05, Vol.15 (5), p.e1006933-e1006933

2019

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Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

Arthritis research & therapy, 2020-10, Vol.22 (1), p.1-232, Article 232

2020

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Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment

Journal of translational medicine, 2021-04, Vol.19 (1), p.165-165, Article 165

2021

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Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics

Cancers, 2023-08, Vol.15 (15), p.4006

2023

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TNFR2 on non‐haematopoietic cells is required for Foxp3+ Treg‐cell function and disease suppression in EAE

European journal of immunology, 2012-02, Vol.42 (2), p.403-412

2012

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Imaging Inflammation of the Pancreatic Islets in Type 1 Diabetes

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (34), p.12634-12639

2004

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Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis

JCI insight, 2023-05, Vol.8 (9)

2023

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Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis

Journal of controlled release, 2016-11, Vol.242, p.16-24

2016

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‘SMASH’ recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models

Annals of the rheumatic diseases, 2021-06, Vol.80 (6), p.714-726

2021

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A Novel Human Interleukin‐23A Overexpressing Mouse Model of Systemic Lupus Erythematosus

Arthritis & rheumatology (Hoboken, N.J.), 2024-07, Vol.76 (7), p.1085-1095

2024

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Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis

Annals of the rheumatic diseases, 2018-06, Vol.77 (6), p.926-934

2018

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Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model

Annals of the rheumatic diseases, 2012-10, Vol.71 (10), p.1716-1723

2012

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Targeting senescence and inflammation in chronic destructive TNF-driven joint pathology

Mechanisms of ageing and development, 2023-09, Vol.214, p.111856-111856, Article 111856

2023

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Discovery of the First‐in‐Class Inhibitors of Hypoxia Up‐Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation

Angewandte Chemie International Edition, 2024-04, Vol.63 (14), p.e202319157-n/a

International ed. in English, 2024

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Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components

eLife, 2024-09, Vol.13

2024

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Discovery of the First‐in‐Class Inhibitors of Hypoxia Up‐Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation

Angewandte Chemie, 2024-04, Vol.136 (14), p.n/a

2024

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Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid arthritis

Journal of translational medicine, 2014-10, Vol.12 (1), p.285-285, Article 285

2014

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Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis

JCI insight, 2018-04, Vol.3 (7)

2018

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Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes

The Journal of clinical investigation, 2005-09, Vol.115 (9), p.2454-2461

2005

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Cover Picture: Eur. J. Immunol. 2/12

European journal of immunology, 2012-02, Vol.42 (2), p.np-n/a

2012

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A non-innovator version of etanercept for treatment of arthritis

Biologicals, 2011-11, Vol.39 (6), p.384-395

2011

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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKK[beta] promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice

Journal of neuroinflammation, 2021-09, Vol.18 (1)

2021

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04.16 Tnf/tnfr2 signalling in mesenchymal cells of joints and aortic heart valves is aetiopathogenic for comorbid arthritis and heart valve disease developing in the tnfΔare/+ mouse model

Annals of the rheumatic diseases, 2017-03, Vol.76 (Suppl 1), p.A48

2017

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04.16 Tnf/tnfr2 signalling in mesenchymal cells of joints and aortic heart valves is aetiopathogenic for comorbid arthritis and heart valve disease developing in the tnf[DELTA]are/+ mouse model

Annals of the rheumatic diseases, 2017-03, Vol.76, p.A48

2017

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Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice

An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory polyarthritis

Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis

Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment

Α Humanized RANKL Transgenic Mouse Model of Progestin-Induced Mammary Carcinogenesis for Evaluation of Novel Therapeutics

TNFR2 on non‐haematopoietic cells is required for Foxp3+ Treg‐cell function and disease suppression in EAE

Imaging Inflammation of the Pancreatic Islets in Type 1 Diabetes

Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis

Improved topical delivery of tacrolimus: A novel composite hydrogel formulation for the treatment of psoriasis

‘SMASH’ recommendations for standardised microscopic arthritis scoring of histological sections from inflammatory arthritis animal models

A Novel Human Interleukin‐23A Overexpressing Mouse Model of Systemic Lupus Erythematosus

Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis

Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model

Targeting senescence and inflammation in chronic destructive TNF-driven joint pathology

Discovery of the First‐in‐Class Inhibitors of Hypoxia Up‐Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation

Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components

Discovery of the First‐in‐Class Inhibitors of Hypoxia Up‐Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation

Collagen II antibody-induced arthritis in Tg1278TNFko mice: optimization of a novel model to assess treatments targeting human TNFα in rheumatoid arthritis

Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis

Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes

Cover Picture: Eur. J. Immunol. 2/12

A non-innovator version of etanercept for treatment of arthritis

Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKK[beta] promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice

04.16 Tnf/tnfr2 signalling in mesenchymal cells of joints and aortic heart valves is aetiopathogenic for comorbid arthritis and heart valve disease developing in the tnfΔare/+ mouse model

04.16 Tnf/tnfr2 signalling in mesenchymal cells of joints and aortic heart valves is aetiopathogenic for comorbid arthritis and heart valve disease developing in the tnf[DELTA]are/+ mouse model

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