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The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin

The Journal of biological chemistry, 2018-06, Vol.293 (24), p.9461-9472

2018

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A novel tubulin inhibitor, 6h, suppresses tumor-associated angiogenesis and shows potent antitumor activity against non–small cell lung cancers

The Journal of biological chemistry, 2022-07, Vol.298 (7), p.102063-102063, Article 102063

2022

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Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2

The Journal of biological chemistry, 2013-05, Vol.288 (22), p.15466-15473

2013

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An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death

The Journal of biological chemistry, 2015-08, Vol.290 (34), p.20841-20855

2015

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Polycystin-2 Cation Channel Function Is under the Control of Microtubular Structures in Primary Cilia of Renal Epithelial Cells

The Journal of biological chemistry, 2006-12, Vol.281 (49), p.37566-37575

2006

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Selective Vulnerability of Dopaminergic Neurons to Microtubule Depolymerization

The Journal of biological chemistry, 2005-10, Vol.280 (40), p.34105-34112

2005

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Parkin Protects Dopaminergic Neurons against Microtubule-depolymerizing Toxins by Attenuating Microtubule-associated Protein Kinase Activation

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.4009-4017

2009

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α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

The Journal of biological chemistry, 2016-02, Vol.291 (6), p.2777-2786

2016

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Parkin Stabilizes Microtubules through Strong Binding Mediated by Three Independent Domains

The Journal of biological chemistry, 2005-04, Vol.280 (17), p.17154-17162

2005

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Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug binding

The Journal of biological chemistry, 2003-04, Vol.278 (16), p.13603

2003

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Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome

The Journal of biological chemistry, 2013-04, Vol.288 (16), p.11378-11383

2013

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Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

The Journal of biological chemistry, 2000-05, Vol.275 (20), p.14838-14845

2000

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The Water Channel Aquaporin-8 Is Mainly Intracellular in Rat Hepatocytes, and Its Plasma Membrane Insertion Is Stimulated by Cyclic AMP

The Journal of biological chemistry, 2001-04, Vol.276 (15), p.12147-12152

2001

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Transition State Analysis of the Coupling of Drug Transport to ATP Hydrolysis by P-glycoprotein

The Journal of biological chemistry, 2003-12, Vol.278 (52), p.52629-52640

2003

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Determination of Four Sequential Stages during Microautophagy in Vitro

The Journal of biological chemistry, 2004-03, Vol.279 (11), p.9987-9996

2004

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Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

The Journal of biological chemistry, 2000-12, Vol.275 (50), p.39272-39278

2000

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Neurotrophic Factors Stabilize Microtubules and Protect against Rotenone Toxicity on Dopaminergic Neurons

The Journal of biological chemistry, 2006-09, Vol.281 (39), p.29391-29400

2006

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Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

The Journal of biological chemistry, 1998-02, Vol.273 (9), p.4928-4936

1998

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Modulation of the Expression of Connective Tissue Growth Factor by Alterations of the Cytoskeleton

The Journal of biological chemistry, 2003-11, Vol.278 (45), p.44305-44311

2003

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The Packing of the Transmembrane Segments of Human Multidrug Resistance P-glycoprotein Is Revealed by Disulfide Cross-linking Analysis

The Journal of biological chemistry, 2000-02, Vol.275 (8), p.5253-5256

2000

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The Basolateral NHE1 Na+/H+ Exchanger Regulates Transepithelial HCO3− Absorption through Actin Cytoskeleton Remodeling in Renal Thick Ascending Limb

The Journal of biological chemistry, 2005-03, Vol.280 (12), p.11439-11447

2005

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Linking Alterations in Tau Phosphorylation and Cleavage during Neuronal Apoptosis

The Journal of biological chemistry, 2004-12, Vol.279 (52), p.54518-54528

2004

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Prestin Surface Expression and Activity Are Augmented by Interaction with MAP1S, a Microtubule-associated Protein

The Journal of biological chemistry, 2010-07, Vol.285 (27), p.20834-20843

2010

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Effects of the Membrane Dipole Potential on the Interaction of Saquinavir with Phospholipid Membranes and Plasma Membrane Receptors of Caco-2 Cells

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.38457-38463

2001

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Nocodazole-induced p53-dependent c-Jun N-terminal Kinase Activation Reduces Apoptosis in Human Colon Carcinoma HCT116 Cells

The Journal of biological chemistry, 2002-11, Vol.277 (46), p.43648-43658

2002

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The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin

A novel tubulin inhibitor, 6h, suppresses tumor-associated angiogenesis and shows potent antitumor activity against non–small cell lung cancers

Control of Myofibroblast Differentiation by Microtubule Dynamics through a Regulated Localization of mDia2

An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death

Polycystin-2 Cation Channel Function Is under the Control of Microtubular Structures in Primary Cilia of Renal Epithelial Cells

Selective Vulnerability of Dopaminergic Neurons to Microtubule Depolymerization

Parkin Protects Dopaminergic Neurons against Microtubule-depolymerizing Toxins by Attenuating Microtubule-associated Protein Kinase Activation

α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

Parkin Stabilizes Microtubules through Strong Binding Mediated by Three Independent Domains

Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug binding

Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome

Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

The Water Channel Aquaporin-8 Is Mainly Intracellular in Rat Hepatocytes, and Its Plasma Membrane Insertion Is Stimulated by Cyclic AMP

Transition State Analysis of the Coupling of Drug Transport to ATP Hydrolysis by P-glycoprotein

Determination of Four Sequential Stages during Microautophagy in Vitro

Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

Neurotrophic Factors Stabilize Microtubules and Protect against Rotenone Toxicity on Dopaminergic Neurons

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

Modulation of the Expression of Connective Tissue Growth Factor by Alterations of the Cytoskeleton

The Packing of the Transmembrane Segments of Human Multidrug Resistance P-glycoprotein Is Revealed by Disulfide Cross-linking Analysis

The Basolateral NHE1 Na+/H+ Exchanger Regulates Transepithelial HCO3− Absorption through Actin Cytoskeleton Remodeling in Renal Thick Ascending Limb

Linking Alterations in Tau Phosphorylation and Cleavage during Neuronal Apoptosis

Prestin Surface Expression and Activity Are Augmented by Interaction with MAP1S, a Microtubule-associated Protein

Effects of the Membrane Dipole Potential on the Interaction of Saquinavir with Phospholipid Membranes and Plasma Membrane Receptors of Caco-2 Cells

Nocodazole-induced p53-dependent c-Jun N-terminal Kinase Activation Reduces Apoptosis in Human Colon Carcinoma HCT116 Cells

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