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Sphingosine-1-phosphate: From insipid lipid to a key regulator

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3371-3384

Spiegel, Sarah

2020

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Functions of the Multifaceted Family of Sphingosine Kinases and Some Close Relatives

The Journal of biological chemistry, 2007-01, Vol.282 (4), p.2125-2129

2007

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Sphingosine 1-Phosphate, a Key Cell Signaling Molecule

The Journal of biological chemistry, 2002-07, Vol.277 (29), p.25851-25854

2002

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Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10477-10486

2010

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Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

The Journal of biological chemistry, 2011-12, Vol.286 (52), p.44380-44390

2011

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SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism

The Journal of biological chemistry, 2005-11, Vol.280 (44), p.37118-37129

2005

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Sphingosine Kinase Type 2 Activation by ERK-mediated Phosphorylation

The Journal of biological chemistry, 2007-04, Vol.282 (16), p.12058-12065

2007

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Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.52487-52492

2004

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Hepatic Apolipoprotein M (ApoM) Overexpression Stimulates Formation of Larger ApoM/Sphingosine 1-Phosphate-enriched Plasma High Density Lipoprotein

The Journal of biological chemistry, 2014-01, Vol.289 (5), p.2801-2814

2014

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Sphingosine Kinase Type 2 Is a Putative BH3-only Protein That Induces Apoptosis

The Journal of biological chemistry, 2003-10, Vol.278 (41), p.40330-40336

2003

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Recycling of Sphingosine Is Regulated by the Concerted Actions of Sphingosine-1-phosphate Phosphohydrolase 1 and Sphingosine Kinase 2

The Journal of biological chemistry, 2007-11, Vol.282 (47), p.34372-34380

2007

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Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells

The Journal of biological chemistry, 2009-02, Vol.284 (6), p.3408-3417

2009

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Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

The Journal of biological chemistry, 2000-06, Vol.275 (26), p.19513-19520

2000

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Ceramide Kinase Mediates Cytokine- and Calcium Ionophore-induced Arachidonic Acid Release

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38206-38213

2003

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Role of Sphingosine Kinase 2 in Cell Migration toward Epidermal Growth Factor

The Journal of biological chemistry, 2005-08, Vol.280 (33), p.29462-29469

2005

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Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104775-104775, Article 104775

2023

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Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

The Journal of biological chemistry, 1998-09, Vol.273 (37), p.23722-23728

1998

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Involvement of Sphingosine in Mitochondria-dependent Fas-induced Apoptosis of Type II Jurkat T Cells

The Journal of biological chemistry, 2000-05, Vol.275 (21), p.15691-15700

2000

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Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking

The Journal of biological chemistry, 2017-02, Vol.292 (8), p.3074-3088

2017

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Sphingosine Kinase Type 1 Induces G12/13-mediated Stress Fiber Formation, yet Promotes Growth and Survival Independent of G Protein-coupled Receptors

The Journal of biological chemistry, 2003-11, Vol.278 (47), p.46452-46460

2003

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Ceramide 1-Phosphate, a Mediator of Phagocytosis

The Journal of biological chemistry, 2005-07, Vol.280 (28), p.26612-26621

2005

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Sphingosine 1-Phosphate Inhibits Activation of Caspases that Cleave Poly(ADP-ribose) Polymerase and Lamins during Fas- and Ceramide-mediated Apoptosis in Jurkat T Lymphocytes

The Journal of biological chemistry, 1998-01, Vol.273 (5), p.2910-2916

1998

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Purification and Characterization of Rat Kidney Sphingosine Kinase

The Journal of biological chemistry, 1998-05, Vol.273 (20), p.12576-12583

1998

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Cloning and Characterization of a Protein Kinase A Anchoring Protein (AKAP)-related Protein That Interacts with and Regulates Sphingosine Kinase 1 Activity

The Journal of biological chemistry, 2002-09, Vol.277 (36), p.32947-32953

2002

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Sphingosine 1-Phosphate-induced Cell Rounding and Neurite Retraction Are Mediated by the G Protein-coupled Receptor H218

The Journal of biological chemistry, 1999-02, Vol.274 (8), p.4626-4632

1999

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Sphingosine-1-phosphate: From insipid lipid to a key regulator

Functions of the Multifaceted Family of Sphingosine Kinases and Some Close Relatives

Sphingosine 1-Phosphate, a Key Cell Signaling Molecule

Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

SphK1 and SphK2, Sphingosine Kinase Isoenzymes with Opposing Functions in Sphingolipid Metabolism

Sphingosine Kinase Type 2 Activation by ERK-mediated Phosphorylation

Mice Deficient in Sphingosine Kinase 1 Are Rendered Lymphopenic by FTY720

Hepatic Apolipoprotein M (ApoM) Overexpression Stimulates Formation of Larger ApoM/Sphingosine 1-Phosphate-enriched Plasma High Density Lipoprotein

Sphingosine Kinase Type 2 Is a Putative BH3-only Protein That Induces Apoptosis

Recycling of Sphingosine Is Regulated by the Concerted Actions of Sphingosine-1-phosphate Phosphohydrolase 1 and Sphingosine Kinase 2

Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells

Molecular Cloning and Functional Characterization of a Novel Mammalian Sphingosine Kinase Type 2 Isoform

Ceramide Kinase Mediates Cytokine- and Calcium Ionophore-induced Arachidonic Acid Release

Role of Sphingosine Kinase 2 in Cell Migration toward Epidermal Growth Factor

Sphingosine-1-phosphate and its receptors in vascular endothelial and lymphatic barrier function

Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase

Involvement of Sphingosine in Mitochondria-dependent Fas-induced Apoptosis of Type II Jurkat T Cells

Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking

Sphingosine Kinase Type 1 Induces G12/13-mediated Stress Fiber Formation, yet Promotes Growth and Survival Independent of G Protein-coupled Receptors

Ceramide 1-Phosphate, a Mediator of Phagocytosis

Sphingosine 1-Phosphate Inhibits Activation of Caspases that Cleave Poly(ADP-ribose) Polymerase and Lamins during Fas- and Ceramide-mediated Apoptosis in Jurkat T Lymphocytes

Purification and Characterization of Rat Kidney Sphingosine Kinase

Cloning and Characterization of a Protein Kinase A Anchoring Protein (AKAP)-related Protein That Interacts with and Regulates Sphingosine Kinase 1 Activity

Sphingosine 1-Phosphate-induced Cell Rounding and Neurite Retraction Are Mediated by the G Protein-coupled Receptor H218

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