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Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation

The Journal of biological chemistry, 2016-08, Vol.291 (32), p.16659-16671

2016

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Thrombin activation of protein C requires prior processing by a liver proprotein convertase

The Journal of biological chemistry, 2017-06, Vol.292 (25), p.10564-10573

2017

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Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10

The Journal of biological chemistry, 2011-07, Vol.286 (26), p.22785-22794

2011

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The Regulated Cell Surface Zymogen Activation of the Proprotein Convertase PC5A Directs the Processing of Its Secretory Substrates

The Journal of biological chemistry, 2008-01, Vol.283 (4), p.2373-2384

2008

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Intestinal Epithelial Cell Differentiation Involves Activation of p38 Mitogen-activated Protein Kinase That Regulates the Homeobox Transcription Factor CDX2

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21885-21894

2001

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Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route

The Journal of biological chemistry, 2009-10, Vol.284 (42), p.28856-28864

2009

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NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.48865-48875

2004

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Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

The Journal of biological chemistry, 2015-07, Vol.290 (30), p.18609-18620

2015

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The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1573-1590

2017

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Nuclear Receptor Co-repressor Is Required to Maintain Proliferation of Normal Intestinal Epithelial Cells in Culture and Down-modulates the Expression of Pigment Epithelium-derived Factor

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.25220-25229

2009

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Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes

The Journal of biological chemistry, 2013-09, Vol.288 (37), p.26410-26418

2013

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Cdk2-dependent Phosphorylation of Homeobox Transcription Factor CDX2 Regulates Its Nuclear Translocation and Proteasome-mediated Degradation in Human Intestinal Epithelial Cells

The Journal of biological chemistry, 2005-05, Vol.280 (18), p.18095-18107

2005

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Proprotein Convertase PC7 Enhances the Activation of the EGF Receptor Pathway through Processing of the EGF Precursor

The Journal of biological chemistry, 2011-03, Vol.286 (11), p.9185-9195

2011

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Effects of the Prosegment and pH on the Activity of PCSK9: EVIDENCE FOR ADDITIONAL PROCESSING EVENTS

The Journal of biological chemistry, 2010-12, Vol.285 (52), p.40965-40978

2010

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G-protein-independent Activation of Tyk2 by the Platelet-activating Factor Receptor

The Journal of biological chemistry, 2001-06, Vol.276 (26), p.24113-24121

2001

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Role of Specific CCAAT/Enhancer-binding Protein Isoforms in Intestinal Epithelial Cells

The Journal of biological chemistry, 2001-11, Vol.276 (47), p.44331-44337

2001

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Proprotein Convertase SKI-1/S1P: IN VITRO ANALYSIS OF LASSA VIRUS GLYCOPROTEIN-DERIVED SUBSTRATES AND EX VIVO VALIDATION OF IRREVERSIBLE PEPTIDE INHIBITORS

The Journal of biological chemistry, 2006-08, Vol.281 (33), p.23471-23481

2006

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Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation

The Journal of biological chemistry, 2009-10, Vol.284 (42), p.28856-28864

2009

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The Proprotein Convertase SKI-1/S1P

The Journal of biological chemistry, 2006-08, Vol.281 (33), p.23471-23481

2006

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NARC-1/PCSK9 and Its Natural Mutants

The Journal of biological chemistry, 2004-11, Vol.279 (47), p.48865-48875

2004

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Negative Regulation of β-Catenin Signaling by Tyrosine Phosphatase SHP-1 in Intestinal Epithelial Cells

The Journal of biological chemistry, 2003-04, Vol.278 (16), p.14274-14283

2003

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Proprotein convertase subtilisin/Kexin type 9 (PCSK9) single domain antibodies are potent inhibitors of low density lipoprotein receptor degradation

The Journal of biological chemistry, 2016-12, Vol.291 (51), p.26586-26586

2016

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Thrombin activation of protein C requires prior processing by a liver proprotein convertase

The Journal of biological chemistry, 2017-08, Vol.292 (33), p.13565-13565

2017

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The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1573-1590

2017

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Negative Regulation of Î²-Catenin Signaling by Tyrosine Phosphatase SHP-1 in Intestinal Epithelial Cells

The Journal of biological chemistry, 2003-04, Vol.278 (16), p.14274

2003

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Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation

Thrombin activation of protein C requires prior processing by a liver proprotein convertase

Furin Is the Major Processing Enzyme of the Cardiac-specific Growth Factor Bone Morphogenetic Protein 10

The Regulated Cell Surface Zymogen Activation of the Proprotein Convertase PC5A Directs the Processing of Its Secretory Substrates

Intestinal Epithelial Cell Differentiation Involves Activation of p38 Mitogen-activated Protein Kinase That Regulates the Homeobox Transcription Factor CDX2

Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other

The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA

Nuclear Receptor Co-repressor Is Required to Maintain Proliferation of Normal Intestinal Epithelial Cells in Culture and Down-modulates the Expression of Pigment Epithelium-derived Factor

Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes

Cdk2-dependent Phosphorylation of Homeobox Transcription Factor CDX2 Regulates Its Nuclear Translocation and Proteasome-mediated Degradation in Human Intestinal Epithelial Cells

Proprotein Convertase PC7 Enhances the Activation of the EGF Receptor Pathway through Processing of the EGF Precursor

Effects of the Prosegment and pH on the Activity of PCSK9: EVIDENCE FOR ADDITIONAL PROCESSING EVENTS

G-protein-independent Activation of Tyk2 by the Platelet-activating Factor Receptor

Role of Specific CCAAT/Enhancer-binding Protein Isoforms in Intestinal Epithelial Cells

Proprotein Convertase SKI-1/S1P: IN VITRO ANALYSIS OF LASSA VIRUS GLYCOPROTEIN-DERIVED SUBSTRATES AND EX VIVO VALIDATION OF IRREVERSIBLE PEPTIDE INHIBITORS

Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation

The Proprotein Convertase SKI-1/S1P

NARC-1/PCSK9 and Its Natural Mutants

Negative Regulation of β-Catenin Signaling by Tyrosine Phosphatase SHP-1 in Intestinal Epithelial Cells

Proprotein convertase subtilisin/Kexin type 9 (PCSK9) single domain antibodies are potent inhibitors of low density lipoprotein receptor degradation

Thrombin activation of protein C requires prior processing by a liver proprotein convertase

The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation

Negative Regulation of Î²-Catenin Signaling by Tyrosine Phosphatase SHP-1 in Intestinal Epithelial Cells

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